Results 71 to 80 of about 26,051 (185)
Right ventricular dysfunction affects 19%–33% of patients With heart failure With preserved ejection fraction and is associated With exercise intolerance, hospitalization, and mortality. Assessing right ventricular function and its coupling with the pulmonary circulation may improve risk stratification and support management tailored to distinct ...
Amarelle Chamoun +13 more
wiley +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 727-729, April 2025.
Wojciech Kosmala +1 more
wiley +1 more source
Abstract An 81‐year‐old man with a history of high‐grade urothelial carcinoma of the bladder and ureter on treatment with atezolizumab and tiragolumab presented to the emergency department with 5 months of malaise, generalized weakness, and fatigue and 2 weeks of subjective fevers. One month prior to presentation, he received an empiric 9‐day course of
Hadi Roudsari +4 more
wiley +1 more source
Nucleic Acid Therapeutics in Rare Disease: From Precision Medicine to Programmable Platforms
ABSTRACT Nucleic acid therapeutics (NATs), including antisense oligonucleotides (ASOs), small interfering RNAs (siRNAs), messenger RNA (mRNA) therapeutics and programmable editing technologies, are reshaping the therapeutic landscape for inherited metabolic and genetic disease.
Tomasz Z. Tomkiewicz +3 more
wiley +1 more source
Neurodegenerative diseases share convergent risk architectures and pathological mechanisms, yet diverge in selective vulnerability, clinical presentation, and therapeutic responsiveness. This review integrates cross‐disease epidemiology, pathophysiology, diagnosis, and treatment, highlighting the transition from symptomatic care toward biomarker‐guided
Zimeng He +4 more
wiley +1 more source
Background: The arrhythmic burden and cardiovascular risks of cardiac amyloidosis compared with other types of restrictive cardiomyopathies (RCM), such as hemochromatosis and cardiac sarcoid, have not been well characterized in the literature.
Andrew Sagalov +7 more
doaj +1 more source
Amyloidosis is a disease caused by the deposition of proteins with an unstable tertiary structure, which coagulate and accumulate in tissues as glycoprotein fibrils.
Nikita S. Averkin +4 more
doaj +1 more source
Among 568 patients with cardiomyopathy, 33 exhibited a restrictive phenotype, including 7 with RCM, 20 with HRCM, and 6 with HDRCM. Pathogenic or likely pathogenic variants were identified in 24 patients (72.7%). Variant carriers had a smaller aortic sinus diameter than non‐carriers (30.79 ± 3.48 vs.
Nianwei Zhou +11 more
wiley +1 more source
A thousand words about the imaging in cardiac amyloidosis
Cardiac amyloidosis is an infiltrative disease which usually occurs under the form of restrictive cardiomyopathy. Advances in the treatment have changed the unfavorable outcomes of this disease. Thus, early diagnosis is essential.
Rafał Dankowski +3 more
doaj +1 more source

