Results 61 to 70 of about 37,864 (312)

Light chain systemic amyloidosis manifested as liver failure complicated with fatal spontaneous splenic rupture: A case report [PDF]

arXiv, 2021
For a patient with manifestations of nausea, abdominal distension, spontaneous splenic rupture, obvious liver enlargement, low red blood cells and platelets, yellow sclera, and spider angioma, Congo red staining of liver and spleen tissues indicated amyloidosis.
arxiv  

Transthyretin cardiac amyloidosis.

Medicine and pharmacy reports, 2021
Transthyretin amyloid cardiomyopathy (ATTR-CM) may be an under recognized cause of heart failure (HF). TTR amyloidosis can be inherited, caused by variants in the TTR gene (ATTRv) or by deposition of wild-type TTR protein (ATTRwt), leading to high mortality if untreated.
Ioan Alexandru Minciună, Ruxandra Beyer, Raluca Tomoaia, Alina Chirilă, Dana Pop, Alexandra Dădârlat-Pop, Simona Manole   +6 more
openaire   +3 more sources

Brain embolic infarction associated with cardiac amyloidosis in a patient with multiple myeloma: a bone marrow-heart-brain crosstalk [PDF]

Precision and Future Medicine, 2018
Cardiac amyloidosis is characterized by the extracellular fibril deposition of amyloid protein in the myocardium. Cerebral embolism caused by cardiac amyloidosis is rare.
Jaeho Kim, Jaehong Park, Sung-Ji Park, Sung Mok Kim, Kihyun Kim, Jong-Won Chung, Oh Young Bang   +6 more
doaj   +1 more source

Break down the barriers of auto‐inflammation: How to deal with a monogenic auto‐inflammatory disease and immuno‐haematological features in 2022?

Immunology, Volume 168, Issue 1, Page 1-17, January 2023., 2023
In the past few years, the spectrum of monogenic systemic auto‐inflammatory diseases has widely expanded beyond the typical recurrent fever. Immuno‐haematological features, as cytopenias, hypogammaglobulinemia, hypereosinophilia, lymphoproliferation and immunodeficiency, have been described in association of several MSAID.
Hélène Vergneault, Capucine Picard, Sophie Georgin‐Lavialle   +2 more
wiley   +1 more source

Prognostic mortality factors in advanced light chain cardiac amyloidosis: A prospective cohort study

ESC Heart Failure
Aims Predicting mortality in severe AL cardiac amyloidosis is challenging due to elevated biomarker levels and limited thresholds for stratifying severe cardiac damage.
Amira Zaroui, Mounira Kharoubi, Romain Gounot, Silvia Oghina, Charlotte Degoutte, Melanie Bezard, Arnault Galat, Soulef Guendouz, Louise Roulin, Vincent Audard, Vincent Leroy, Emmanuel Teiger, Elsa Poullot, Valérie Molinier‐Frenkel, Fabien Le Bras, Karim Belhadj, Jean‐Philippe Bastard, Soraya Fellahi, Jason Shourick, Francois Lemonier, Thibaud Damy   +20 more
doaj   +1 more source

Management of Cardiac Implantable Electronic Devices in Patients With Severe Symptomatic Tricuspid Regurgitation—Proposed Algorithm and Selected Case Examples

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Severe tricuspid regurgitation (TR) is associated with significant morbidity and mortality. Management of severe TR includes treatment of the underlying cause(s), medical therapy and less commonly surgical tricuspid valve repair. Newer transcatheter tricuspid valve repair devices show promise for those patients who remain symptomatic with ...
Mina M. Kerolos, Kevin Lee, David M. Najman, Mark D. Metzl, Mark J. Ricciardi   +4 more
wiley   +1 more source

Liver‐directed drugs for transthyretin‐mediated amyloidosis

Journal of the Peripheral Nervous System, Volume 27, Issue 4, Page 228-237, December 2022., 2022
Abstract Transthyretin‐mediated amyloidosis (ATTR) is a rare, under‐recognized, progressively debilitating, fatal disease caused by the aggregation and extracellular deposition of amyloid transthyretin (TTR) fibrils in multiple organs and tissues throughout the body.
Thomas H. Brannagan 3rd, John L. Berk, Julian D. Gillmore, Mathew S. Maurer, Márcia Waddington‐Cruz, Marianna Fontana, Ahmad Masri, Laura Obici, Michela Brambatti, Brenda F. Baker, Lisa A. Hannan, Gustavo Buchele, Nick J. Viney, Teresa Coelho, Jose Nativi‐Nicolau   +14 more
wiley   +1 more source

Progression and prognostic significance of electrocardiographic findings in patients with cardiac amyloidosis. [PDF]

ESC Heart Fail
Abstract Aims This study aimed to evaluate the change of the main electrocardiographic (ECG) characteristics and their prognostic role across the main subtypes of cardiac amyloidosis [light‐chain amyloidosis (AL) and hereditary (ATTRv) and wild‐type transthyretin amyloidosis (ATTRwt)].
Argirò A, Zampieri M, Mazzoni C, Fumagalli C, Baccini M, Mattei A, Cipriani A, De Michieli L, Porcari A, Sinagra G, Merlo M, Tini G, Musumeci B, Russo D, Vianello PF, Canepa M, Licordari R, di Bella G, Rapezzi C, Perfetto F, Cappelli F.   +20 more
europepmc   +2 more sources

Impact of Elevated Preprocedural Left Ventricular Filling Pressure on Prognosis of Mild Paravalvular Regurgitation Following Transcatheter Aortic Valve Replacement

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Paravalvular regurgitation (PVR) following transcatheter aortic valve replacement (TAVR) is a complication linked to poor outcomes. The prognostic impact of mild PVR, particularly in patients with elevated preprocedural left ventricular (LV) filling pressure, remains uncertain.
Shumpei Kosugi, Isamu Mizote, Daisuke Nakamura, Hiroki Sugae, Yutaka Matsuhiro, Shota Okuno, Ai Kawamura, Kizuku Yamashita, Koichi Maeda, Kazuo Shimamura, Tomoharu Dohi, Yasuharu Takeda, Yasushi Sakata   +12 more
wiley   +1 more source

Combination therapy using tafamidis and neurohormonal blockers for cardiac amyloidosis and a reduced ejection fraction: a case report

Journal of International Medical Research, 2022
Cardiac amyloidosis usually presents with diastolic dysfunction, but sometimes systolic dysfunction develops, particularly at its advanced stage. However, the therapeutic strategy for patients with cardiac amyloidosis and systolic dysfunction remains ...
Teruhiko Imamura, Toshihide Izumida, Masakazu Hori, Shuhei Tanaka, Koichiro Kinugawa   +4 more
doaj   +1 more source