RationaleDiscerning cardiac myocyte cell cycle behavior is challenging owing to commingled cell types with higher proliferative activity.ObjectiveTo investigate cardiac myocyte cell cycle activity in development and the early postnatal period.Methods and
core
Advanced Materials, EarlyView.Lipid nanoparticles (LNPs) of unconventional composition and defined structures are investigated as small oligonucleotide carriers. A composition is identified that outperforms Onpattro in cargo delivery to HeLa cells. The structure of these LNPs resembles a micellar cubic phase not commonly associated with high‐performing LNPs.
Miina Ojansivu +9 more
wiley +1 more source
Towards Cardiac MRI Foundation Models: Comprehensive Visual-Tabular Representations for Whole-Heart Assessment and Beyond [PDF]
arXivCardiac magnetic resonance imaging is the gold standard for non-invasive cardiac assessment, offering rich spatio-temporal views of the cardiac anatomy and physiology. Patient-level health factors, such as demographics, metabolic, and lifestyle, are known to substantially influence cardiovascular health and disease risk, yet remain uncaptured by CMR ...
arxiv
Ca 2+ Transport by Mitochondria and Its Possible Role in the Cardiac Relaxation Cycle [PDF]
, 1974 A L Lehninger
openalex +1 more source
Materials Advances in Devices for Heart Disease Interventions
Advanced Materials, EarlyView.This review examines the crucial role of materials in heart disease interventions, focusing on strategies for monitoring, managing, and repairing heart conditions. It discusses the material requirements for medical devices, highlighting recent innovations and their impact on cardiovascular health.
Gagan K. Jalandhra +11 more
wiley +1 more source
Microneedles with Interdigitated Electrodes for In Situ Impedimetric VEGF Sensing
Advanced Materials Interfaces, EarlyView.An electrochemical device for transdermal monitoring based on flexible polylactide microneedles with interdigitated electrodes enables continuous monitoring of vascular endothelial growth factor (VEGF) in interstitial fluid. Gold‐coated microneedles functionalized with anti‐VEGF antibodies, provide an in situ detection platform with high sensitivity ...
Ritu Das +10 more
wiley +1 more source
New Perspectives on Semiconducting Conjugated Oligomers for Neuromodulation in Hydra vulgaris
Advanced Materials Interfaces, EarlyView.Semiconducting organic compounds, thiophene‐based, modify the rhythmic electrical activity of the cnidarian Hydra vulgaris acting on specific neuronal circuits. The ETE‐S trimer also forms electronically conducting wires in the living tissues of the animal.
Giuseppina Tommasini +7 more
wiley +1 more source
Ultrasonic tissue characterization of human hypertrophied hearts in vivo with cardiac cycle-dependent variation in integrated backscatter. [PDF]
, 1989 T Masuyama +5 more
openalex +1 more source
Stress induced lncRNA Lockd inhibits proliferation and angiogenesis of myocardial endothelial cells and promotes maladaptive cardiac remodelling during pressure overload [PDF]
Myocardial endothelial cells play a pivotal role in modulating the cardiac stress response and influencing heart growth and function. While past research has predominantly focused on endothelial-derived proteins, recent evidence points to the involvement
Grein, Steve
core +1 more source
The Role of Silicon Technology in Organ‐On‐Chip: Current Status and Future Perspective
Advanced Materials Technologies, EarlyView.This review explores the potential of silicon micro‐nanofabrication technologies in advancing organ‐on‐chip systems. The integration of actuation and sensing modalities, highlight emerging technologies is discussed for combining silicon‐based and polymer‐based components, and emphasize the need for robust, high‐throughput, and customizable organ‐on ...
Frøydis Sved Skottvoll +2 more
wiley +1 more source