Results 201 to 210 of about 335,049 (297)

Reply to DeVore, G.R. Determination of the Same Cardiac Cycle When Analyzing Cine Clips for Use by FetalHQ to Assess Intraobserver and Interobserver Variability. Comment on "Mlodawski et al. Reproducibility Challenges in Fetal Cardiac Function Analysis with 2D Speckle-Tracking Echocardiography: Insights from FetalHQ. <i>J. Clin. Med.</i> 2025, <i>14</i>, 3301". [PDF]

J Clin Med
Mlodawski J, Zmelonek-Znamirowska A, Pawlik L, Mlodawska M, Swiercz G.   +4 more
europepmc   +1 more source

Full‐Body AI Agent: A Perspective on Multi‐Scale Collaborative AI for Systemic Biology and Precision Medicine

Advanced Science, EarlyView.
We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang, Jiajia Liu, Jianguo Wen, Yangyang Luo, Zhiwei Fan, Liren Yang, Xi Hu, Ruihan Luo, Yankai Yu, Sophia Li, Weiling Zhao, Xiaobo Zhou   +11 more
wiley   +1 more source

Measurement of pressure dependent variations in local pulse wave velocity within a cardiac cycle from forward travelling pulse waves. [PDF]

Sci Rep
Manoj R, Raj KV, Nabeel PM, Sivaprakasam M, Joseph J.   +4 more
europepmc   +1 more source

The 3-dimensional cardiac hype cycle [PDF]

The Journal of Thoracic and Cardiovascular Surgery, 2018
openaire   +2 more sources

Impact of Estrous Cycle on Cardiac Function

Heart disease is the leading cause of death in the U.S. Premenopausal women generally have lower cardiovascular disease (CVD) rates compared to men, but after menopause, their risk exceeds that of men, largely due to decreased estrogen and progesterone ...
Nguyen, Thaotho Hoang
core  

NUDT21 Drives T‐Cell Acute Lymphoblastic Leukemia Through Dual Regulation of Alternative Polyadenylation and Transcriptional Activation

Advanced Science, EarlyView.
In summary, our study defines a coordinated oncogenic model in which NUDT21 integrates alternative polyadenylation–dependent UBE2D3 stabilization and transcriptional activation to sustain MYC‐driven T‐ALL cell survival, thereby establishing NUDT21 as a central regulatory node and a promising therapeutic target.
Conglian Qiu, Jianwei Wang, Zhiheng Li, Qi Ji, Hui Zhang, Qinyi Zhang, Senlin Zhang, Juanjuan Yu, Yanfang Tao, Yijun Wu, Chunxia Shi, Zong Zai, Zimu Zhang, Yizhen Li, Zhenjiang Bai, Shaoyan Hu, Jian Pan, Yang Yang, Shuiyan Wu   +18 more
wiley   +1 more source

Examining the upper frequency limit of dynamic cerebral autoregulation: Considerations across the cardiac cycle during eucapnia. [PDF]

Exp Physiol
Burma JS, Neill MG, Fletcher EKS, Dennett BE, Johnson NE, Javra R, Griffiths JK, Smirl JD.   +7 more
europepmc   +1 more source

Connexin 43‐Enriched Vesicles Improve Synchronization in hiPSC‐Derived Cardiomyocytes

Advanced Science, EarlyView.
Plasma membrane‐derived Connectosomes enriched in connexin‐43 are produced from donor hiPSCs and applied to hiPSC‐derived cardiomyocytes (hiPSC‐CMs). Connexin‐43 channels on Connectosomes remain functional, strengthening intercellular electrochemical coupling and increasing network synchronization over time.
Nima Momtahan, Anna K. McClain, Andrea Trementozzi, Sogu Sohn, Lingxia Qiao, Chi Zhao, Padmini Rangamani, Jeanne C. Stachowiak, Janet Zoldan   +8 more
wiley   +1 more source

Calcium Signal Analysis in the Zebrafish Heart via Phase Matching of the Cardiac Cycle. [PDF]

Bio Protoc
Zhang RJ, Vermot J, Gherardi R, Fukui H, Chow RW.   +4 more
europepmc   +1 more source

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

Advanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi, Pierre Parutto, Yuyi Zhang, Tasuku Konno, Cecile Crapart, Raquel Pereira, John P. Franklin, Mosab Ali Awadelkareem, Daniel C Maddison, Michael J. Devine, Edgar R. Gomes, Joseph Chambers, Elena Koslover, Edward Avezov   +13 more
wiley   +1 more source