Over expression of Plk1 does not induce cell division in rat cardiac myocytes in vitro. [PDF]
PLoS ONE, 2009 BACKGROUND:Mammalian cardiac myocytes withdraw from the cell cycle during post-natal development, resulting in a non-proliferating, fully differentiated adult phenotype that is unable to repair damage to the myocardium, such as occurs following a ...
Carmen H Coxon +3 more
doaj +1 more source
Interactions between cardiac activity and conscious somatosensory perception
, 2019 Fluctuations in the heart's activity can modulate the access of external stimuli to consciousness. The link between perceptual awareness and cardiac signals has been investigated mainly in the visual and auditory domain. Here, we investigated whether the
Al, E. +5 more
core +1 more source
RNAase III-Type Enzyme Dicer Regulates Mitochondrial Fatty Acid Oxidative Metabolism in Cardiac Mesenchymal Stem Cells [PDF]
, 2019 Cardiac mesenchymal stem cells (C-MSC) play a key role in maintaining normal cardiac function under physiological and pathological conditions. Glycolysis and mitochondrial oxidative phosphorylation predominately account for energy production in C-MSC ...
Jin, Yue +5 more
core +1 more source
Early Postnatal Cardiac Stress Does Not Influence Ventricular Cardiomyocyte Cell-Cycle Withdrawal
Journal of Cardiovascular Development and Disease, 2021 Congenital heart disease (CHD) is the most common birth defect. After birth, patients with CHD may suffer from cardiac stress resulting from abnormal loading conditions.
Marie Günthel +4 more
doaj +1 more source
Thoracic aorta cardiac-cycle related dynamic changes assessed with a 256-slice CT scanner [PDF]
, 2013 Objective: The aim of our study was to demonstrate whether the dynamic changes previously documented at the ascending and abdominal aorta are replicated at the thoracic aorta.
Capuñay, Carlos +7 more
core +1 more source
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Systolic phases of the cardiac cycle in children [PDF]
The American Journal of Cardiology, 1969 The duration of the systolic phases of the cardiac cycle in 390 normal children was determined from high-speed simultaneous recordings of the electrocardiogram, phonocardiogram, apexcardiogram, and carotid pulse. Data were obtained on children 1 mo to 13 years of age and analyzed to define the independent effects of aging and heart rate on the systolic
D, Golde, L, Burstin
openaire +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Cardiac cycle gated cognitive-emotional control in superior frontal cortices
NeuroImage, 2020 Accumulating evidence suggests that peripheral physiological processes, such as the cardiac cycle, impact the individual's ability to appropriately exert control over behavior and emotional responses.
Nico Adelhöfer +2 more
doaj +1 more source
The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells
FEBS Open Bio, EarlyView.We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel +8 more
wiley +1 more source