Results 81 to 90 of about 4,585,967 (340)
Shunt quantification in congenital heart disease based on two-dimensional speckle tracking [PDF]
, 2012 In this work we investigated how high frame rate speckle tracking based on plane wave imaging could be used to improve the quantification of peak velocities in shunt flows due to septal defects.
Fadnes, Solveig +4 more
core +2 more sources
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source
Coupled dynamics of voltage and calcium in paced cardiac cells [PDF]
, 2004 We investigate numerically and analytically the coupled dynamics of transmembrane voltage and intracellular calcium cycling in paced cardiac cells using a detailed physiological model and its reduction to a three-dimensional discrete map. The results provide a theoretical framework to interpret various experimentally observed modes of instability ...
arxiv +1 more source
Estimation of elastic and viscous properties of the left ventricle based on annulus plane harmonic behavior [PDF]
, 2006 Assessment of left ventricular (LV) function with an emphasis on contractility has been a challenge in cardiac mechanics during the recent decades. The LV function is usually described by the LV pressurevolume (P-V) diagram. The standard P-V diagrams
Gharib, Morteza +4 more
core +1 more source
Molecular Oncology, EarlyView.Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit +19 more
wiley +1 more source
Epigenetic regulation of cardiac myocyte differentiation
Frontiers in Genetics, 2014 Cardiac myocytes proliferate robustly during fetal life but withdraw permanently from the cell cycle soon after birth and undergo terminal differentiation.
Kyohei eOyama +4 more
doaj +1 more source
Frontiers in Pharmacology, 2022 The bromodomain and extra-terminal domain proteins (BETs) family serve as epigenetic “readers”, which recognize the acetylated histones and recruit transcriptional regulator complexes to chromatin, eventually regulating gene transcription.
Zhirong Lin +6 more
doaj +1 more source
Left Ventricle Quantification Using Direct Regression with Segmentation Regularization and Ensembles of Pretrained 2D and 3D CNNs [PDF]
, 2019 Cardiac left ventricle (LV) quantification provides a tool for diagnosing cardiac diseases. Automatic calculation of all relevant LV indices from cardiac MR images is an intricate task due to large variations among patients and deformation during the cardiac cycle. Typical methods are based on segmentation of the myocardium or direct regression from MR
arxiv +1 more source
End-to-End Deep Learning Model for Cardiac Cycle Synchronization from Multi-View Angiographic Sequences [PDF]
, 2020 Dynamic reconstructions (3D+T) of coronary arteries could give important perfusion details to clinicians. Temporal matching of the different views, which may not be acquired simultaneously, is a prerequisite for an accurate stereo-matching of the coronary segments.
arxiv +1 more source
Molecular Oncology, EarlyView.Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma +9 more
wiley +1 more source