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CCR2 deficiency protects against doxorubicin-induced cardiac dysfunction through enhanced IL12B-dependent autophagy. [PDF]
Hu L +8 more
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Anaplastic Thyroid Carcinoma With Cardiac Dysfunction Developed During Combination Therapy With Dabrafenib and Trametinib. [PDF]
Maezumi S +4 more
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Cardiac dysfunction in cirrhosis
Best Practice & Research Clinical Gastroenterology, 2007Cirrhosis is known to be associated with numerous cardiovascular abnormalities. These include increased cardiac output and decreased arterial pressure and total peripheral resistance. Despite this increased baseline cardiac output, patients with cirrhosis show an attenuated systolic and diastolic function in the face of pharmacological, physiological ...
Ralph F, Lee +2 more
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Sarcopenia and Cardiac Dysfunction
Cardiology in Review, 2019Although muscle loss is part of the natural course of human aging, sarcopenia has been associated with an increased risk of physical disability and mortality in older patients. Many heart failure patients concomitantly develop deficits in muscle mass and strength, resulting in decreased quality of life and exercise capacity.
Alexandra, Wong, William, Frishman
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Cardiac dysfunction in cirrhosis
Hepatology Research, 2003In cirrhosis, cardiac symptoms and physical signs occur as the liver functions worsen. Cirrhosis is associated with hyperdynamic circulation and beta-adrenergic system activation responsible for the cardiovascular changes. The purpose of the present study was to explore the cardiovascular response to exercise in cirrhotic patients.
Duran, Kaya +4 more
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Cardiac Function and Dysfunction in Sepsis
Clinics in Chest Medicine, 2016Cardiac function and dysfunction are important in the clinical outcomes of sepsis and septic shock. Cardiac dysfunction is not a single entity, but is a broad spectrum of syndromes that result in biventricular cardiac dysfunction manifested by both systolic and diastolic dysfunction and is influenced by cardiac loading conditions (ie, preload and ...
Margaret M Parker, Kimberly E Fenton
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Trastuzumab-Related Cardiac Dysfunction
Journal of the National Comprehensive Cancer Network, 2011The use of trastuzumab in the adjuvant and metastatic treatment of breast cancer is associated with both symptomatic and asymptomatic cardiotoxicity. The long-term significance of these events, isolating known cardiotoxic effects of anthracyclines from those of trastuzumab, and the appropriateness of referring to trastuzumab-related cardiotoxicity as ...
Melinda L, Telli, Ronald M, Witteles
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Subclinical Cardiac Dysfunction in Sarcoidosis
Chest, 1991Clinically apparent myocardial disease is infrequent in sarcoidosis. However, autopsy data show myocardial involvement in up to 30 percent of patients. Unexplained exertional symptomatology is a common complaint in patients with sarcoidosis. In this study, we investigated whether abnormal cardiac function might limit exercise performance in patients ...
W J, Gibbons +8 more
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