Results 101 to 110 of about 96,033 (299)

Assessing the impact and safety of implantable cardioverter defibrillators in treating catecholaminergic polymorphic ventricular tachycardia: a systematic review and meta-analysis protocol

BMJ Open
Background While the guidelines acknowledge the anticipated benefits of using an implantable cardioverter defibrillator (ICD) in individuals with catecholaminergic polymorphic ventricular tachycardia (CPVT).
Xianhui Zhou, Zhenyu Dong, Shuai Shang, Yali Mu, Rukiya Yusup, Yaodong Li, Yanmei Lu, Baopeng Tang   +7 more
doaj   +1 more source

Osborn Waves: History and Significance [PDF]

, 2004
The Osborn wave is a deflection with a dome or hump configuration occurring at the R-ST junction (J point) on the ECG (Fig. 1). In the historical view, different names have been used for this wave in the medical literature, such as “camel-hump sign ...
Atarashi, Hirotsugu, Hirayama, Yoshiyuki, Katoh, Takao, Kobayashi, Yoshinori, Kodani, Eitaroh, Maruyama, Mitsunori, Takano, Teruo   +6 more
core   +2 more sources

Semaglutide normalizes increased cardiomyocyte calcium transients in a rat model of high fat diet‐induced obesity

ESC Heart Failure, Volume 12, Issue 2, Page 1386-1397, April 2025.
Sequeira et al. reveal how the glucagon‐like peptide‐1 receptor agonist (GLP‐1‐RA) semaglutide restores cardiomyocyte function in rats subjected to a high‐fat/high‐fructose diet (HFD). Employing fluorescence‐ and patch‐clamp technology in isolated cardiac myocytes, they demonstrate that semaglutide reverses HFD‐induced activation of L‐type calcium ...
Vasco Sequeira, Julia Theisen, Katharina J. Ermer, Marie Oertel, Anton Xu, David Weissman, Katharina Ecker, Jan Dudek, Martin Fassnacht, Alexander Nickel, Michael Kohlhaas, Christoph Maack, Ulrich Dischinger   +12 more
wiley   +1 more source

Novel SCN5A gene mutation in a patient affected by multifocal ectopic premature Purkinje‐related contractions syndrome

ESC Heart Failure
We report the case of a 36‐year‐old woman who presented to the emergency department complaining of palpitations and asthenia. Investigations showed frequent ventricular ectopy and severe left ventricular ejection fraction impairment.
Nicoletta Ventrella, Lorenzo Bianchini, Stefania Riva, Francesca Pizzamiglio, Maria Antonietta Dessanai, Fabrizio Tundo, Tommaso Sattin, Francesca De Lio, Selene Cellucci, Claudio Tondo   +9 more
doaj   +1 more source

Venoplasty of a chronic venous occlusion with ‘diathermy’ for cardiac device lead placement

Indian Pacing and Electrophysiology Journal, 2019
Venous revascularization is an approach used in patients with total venous occlusion requiring venous access for cardiac device lead placement. Several percutaneous approaches to venous revascularization have been proposed.
Enes Elvin Gul, Reda Abuelatta, Sohaib Haseeb, Mohammad Melhem, Osama Al Amoudi   +4 more
doaj   +1 more source

Neonatal seizures: Advances in diagnosis and management

Epilepsia Open, EarlyView.
Abstract The International League Against Epilepsy (ILAE) created the ILAE Neonatal Task Force that classified neonatal seizures, defined neonatal epilepsy syndromes, and specified treatment guidelines. These frameworks, in addition to improved access to genetic testing and other recent advances, have revolutionized the diagnosis and management of ...
Elissa G. Yozawitz, Ronit M. Pressler, Eli M. Mizrahi   +2 more
wiley   +1 more source

Artificial intelligence in preclinical epilepsy research: Current state, potential, and challenges

Epilepsia Open, EarlyView.
Abstract Preclinical translational epilepsy research uses animal models to better understand the mechanisms underlying epilepsy and its comorbidities, as well as to analyze and develop potential treatments that may mitigate this neurological disorder and its associated conditions. Artificial intelligence (AI) has emerged as a transformative tool across
Jesús Servando Medel‐Matus, Cesar Santana‐Gomez, Ruby G. Escalante, Dominique Duncan, Pedro F. Viana, Giulia Sofia Cereda, Naoto Kuroda, Aristea S. Galanopoulou   +7 more
wiley   +1 more source

Truths and Lies from the Polysomnography ECG Recording: An Electrophysiologist Perspective

Case Reports in Medicine, 2009
Polysomnography remains the gold standard for diagnosis of Sleep Apnea (SA) and evaluation of the apnea/hypopnea index (AHI) which is used as the primary index of SA severity.
Adrian Baranchuk, Christina Quinlan, Kevin Michael, Christopher S. Simpson, Damian P. Redfearn, Michael Fitzpatrick   +5 more
doaj   +1 more source

Movement Disorders Associated with 22q11.2 Microdeletion: A Scoping Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Movement disorders have recently emerged as important neurologic manifestations of the 22q11.2 microdeletion that affects nearly one in every 2000 live births. Objective We aimed to map the existing evidence regarding the spectrum, diagnosis and treatment, and etiopathogenesis of movement disorders associated with 22q11.2 ...
Nikolai Gil D. Reyes, Daniel G. Di Luca, Connie Marras, Erik Boot, Ryan K.C. Yuen, Anthony E. Lang, Anne S. Bassett   +6 more
wiley   +1 more source

Analytical Solutions for the Cardiac Extracellular‐Membrane‐Intracellular Model

Mathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT The cardiac extracellular‐membrane‐intracellular (EMI) model is a novel mathematical framework for cardiac electrophysiology simulations. The cardiac EMI model provides a more detailed description of the heart's electrical activity compared to traditional monodomain and bidomain models, potentially making it better‐suited for understanding the
Carlos Ballesteros, Alexei Cheviakov, Raymond J. Spiteri   +2 more
wiley   +1 more source