Synergistic effects of ion transporter and MAP kinase pathway inhibitors in melanoma
Treatment responses of melanoma patients to MAPK pathway inhibitors are often limited. Here, the authors show that combining cardiac glycosides with MAPK inhibitors improves tumor regression by inducing intracellular acidification, mitochondrial calcium ...
Ugur Eskiocak +12 more
doaj +1 more source
Phytochemical Screening and Antimicrobial Studies of Stem and Root Extracts of Crateva adansonii [PDF]
Aim: This study was designed to explore the phytochemical and antimicrobial screening of the stem and root extracts of Crateva adansonii. Place and Duration of Study: Sample: Iyesi village, Ota, Ogun State, and analysis carried out at Department of ...
Ajanaku , C. O. +6 more
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Selective cell death of latently HIV-infected CD4+ T cells mediated by autosis inducing nanopeptides. [PDF]
Despite significant advances in the treatment of human immunodeficiency virus type-1 (HIV) infection, antiretroviral therapy only suppresses viral replication but is unable to eliminate infection. Thus, discontinuation of antiretrovirals results in viral
Campbell, Grant R +6 more
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Inotropic and chronotropic effects of methanol extract of Aquilaria agallocha on rabbit heart
Aquilaria agallocha Roxb. (Thymelaeceae) heartwood is used in cardiac failure; however, its cardiotonic properties are poorly understood at a pharmacological level. This study investigated methanol extract of A.
Nawazish-i-Husain Syed +3 more
doaj
The mechanistic role of cardiac glycosides in DNA damage response and repair signaling. [PDF]
Ainembabazi D, Zhang Y, Turchi JJ.
europepmc +1 more source
Antibacterial Spectrum Of Extracts Of ·Ocimum Gratissimum L.{BASIL) And Xylopia Aetiopica A. Rich (DUNAL). [PDF]
Preliminary phytochemical analysis showed that fruits of X. aetiopica contain phenolic compounds (including tannins) and cardiac glycosides while leaves of 0. gratissimum possess these components and also saponins. Antibacterial activities of aqueous,
De, N, James, N.A ..
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Cardiac glycoside binding sites in cultured heart muscle cells [PDF]
Erdmann, E. +4 more
core +1 more source
Evidence for Cardiac Glycosides in Foliage of Colorado Potato Beetle-Resistant Solanum okadae. [PDF]
McCoy HJ +6 more
europepmc +1 more source
Synthesis and Biological Evaluation of Cardiac Glycosides for Cancer Therapy by Targeting the DNA Damage Response. [PDF]
Ainembabazi D +4 more
europepmc +1 more source

