Results 11 to 20 of about 177,041 (162)

Human stem cell-based in vitro model of cardiac hypertrophy [PDF]

open access: yes, 2022
Cardiac hypertrophy is an important and independent risk factor for the development of cardiomyopathy that may lead to heart failure. To accelerate the development of new and improved treatment options, relevant disease models that can be used to ...
Johansson, Markus
core   +1 more source

Actin-Binding Proteins in Cardiac Hypertrophy

open access: yes, 2022
The heart reacts to a large number of pathological stimuli through cardiac hypertrophy, which finally can lead to heart failure. However, the molecular mechanisms of cardiac hypertrophy remain elusive.
Zhanhong Ren   +7 more
core   +1 more source

Mitochondrial Dysfunction in Arrhythmia and Cardiac Hypertrophy

open access: yes, 2023
Arrhythmia and cardiac hypertrophy are two very common cardiovascular diseases that can lead to heart failure and even sudden death, thus presenting a serious threat to human life and health.
Mengying Fan   +10 more
core   +1 more source

The oxoglutarate receptor 1 (OXGR1) modulates pressure overload-induced cardiac hypertrophy in mice [PDF]

open access: yes, 2016
The G-protein-coupled receptors (GPCRs) family of proteins play essential roles in the heart, including in the regulation of cardiac hypertrophy. One member of this family, the oxoglutarate receptor 1 (OXGR1), may have a crucial role in the heart because
Mamas
core   +1 more source

Pharmacological management of cardiac hypertrophy

open access: yes, 2023
Cardiac hypertrophy is a condition in which the heart muscle thickens and enlarge, often as a result of chronic pressure overload or other forms of stress.
Kyzer, Ori Michael
core  

Cardiac ISL1-Interacting Protein, a Cardioprotective Factor, Inhibits the Transition From Cardiac Hypertrophy to Heart Failure

open access: yes, 2022
Heart failure is characterized by the inability of the heart to pump effectively and generate proper blood circulation to meet the body’s needs; it is a devastating condition that affects more than 100 million people globally. In spite of this, little is
Ma, Q   +15 more
core   +1 more source

ANGPTL8 is a negative regulator in pathological cardiac hypertrophy

open access: yes, 2022
Pathological cardiac hypertrophy is an independent risk factor for heart failure and is considered a target for the treatment of heart failure. However, the mechanisms underlying pathological cardiac hypertrophy remain largely unknown.
Wang, Ziyuan   +25 more
core   +1 more source

Extracellular vesicular microRNAs and cardiac hypertrophy [PDF]

open access: yes
Cardiac hypertrophy is an adaptive response to pressure or volume overload such as hypertension and ischemic heart diseases. Sustained cardiac hypertrophy eventually leads to heart failure.
Xiulian Wang   +3 more
core   +1 more source

miRNA and Cardiac Hypertrophy

open access: yes, 2019
Cardiac hypertrophy is a frequent pathological reaction to hypertension, pulmonary hypertension, and other cardiovascular diseases. A typical feature of myocardial remodeling, cardiac hypertrophy can lead to heart failure and ultimately death.
Liu, Chunlian, Huo, Zhenghao, Gu, Jiwei
core   +2 more sources

Table3_Identification of circular RNAs in cardiac hypertrophy and cardiac fibrosis.XLSX

open access: yes, 2022
Cardiac hypertrophy initially serves as an adaptive response to physiological and pathological stimuli. Sustained hypertrophy progress to pathological cardiac hypertrophy, cardiac fibrosis and ultimately lead to heart failure, one of the leading medical ...
Yan Chen (4308)   +8 more
core   +1 more source

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