Results 121 to 130 of about 1,441,839 (397)
Cardiac Myocytes and Mechanosensation
, 2012 Mechanosensation is a fundamental process in biology and may have been developed by the early cells in response to hypo-osmotic stress [1]. With the evolution of different cell types and the appearance of multi-cellular organisms the mechanisms of mechanosensation and the corresponding transmission of signals became more complex and evolved in ...
Buyandelger, Byambajav, Knöll, Ralph
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Mitochondrial membrane potential in cardiac myocytes
Physiological Research, 2002 Mitochondria are involved in cellular functions that transcend the traditional role of these organelles as the energy factory of the cell. Their relative inaccessibility and the difficulties involved in attempts to study them in their natural environment - the cytosol - has delayed much of this understanding and they still have many secrets to yield ...
L, Skárka, B, Ostádal
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Biomaterial design strategies for enhancing mitochondrial transplantation therapy
BMEMat, EarlyView.Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang +12 more
wiley +1 more source
Diabetes Increases the Vulnerability of the Cardiac Mitochondrial Network to Criticality
Frontiers in Physiology, 2020 Mitochondrial criticality describes a state in which the mitochondrial cardiac network under intense oxidative stress becomes very sensitive to small perturbations, leading from local to cell-wide depolarization and synchronized oscillations that may ...
Larissa Vetter +14 more
doaj +1 more source
Effects of Polyphenols on Oxidative Stress-Mediated Injury in Cardiomyocytes [PDF]
, 2017 Cardiovascular diseases are the main cause of mortality and morbidity in the world. Hypertension, ischemia/reperfusion, diabetes and anti-cancer drugs contribute to heart failure through oxidative and nitrosative stresses which cause cardiomyocytes ...
Bei, Roberto +10 more
core +2 more sources
Enhancing Macroautophagy Protects against Ischemia/Reperfusion Injury in Cardiac Myocytes*
Journal of Biological Chemistry, 2006 Cardiac myocytes undergo programmed cell death as a result of ischemia/reperfusion (I/R). One feature of I/R injury is the increased presence of autophagosomes.
A. Hamacher-Brady, N. Brady, R. Gottlieb
semanticscholar +1 more source
Contemporary and Emerging Therapies in the Management of Refractory Angina: A Clinical Review
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Refractory angina (RA) represents a growing challenge in clinical cardiology, particularly in patients with obstructive coronary artery disease (CAD) who remain symptomatic despite optimal medical therapy and who are not candidates for revascularization.
Alex Angers‐Goulet +4 more
wiley +1 more source
Frontiers in Physiology, 2012 Diabetic heart disease is a distinct clinical entity that can progress to heart failure and sudden death. However, the mechanisms responsible for the alterations in excitation-contraction coupling leading to cardiac dysfunction during diabetes are not ...
Allyson eKranstuber +6 more
doaj +1 more source
Remodelling of human atrial K+ currents but not ion channel expression by chronic β-blockade [PDF]
, 2012 Chronic β-adrenoceptor antagonist (β-blocker) treatment in patients is associated with a potentially anti-arrhythmic prolongation of the atrial action potential duration (APD), which may involve remodelling of repolarising K+ currents.
A Alday +46 more
core +1 more source
Cardiac myocyte apoptosis [PDF]
European Heart Journal, 1999 S A, Cook, P A, Poole-Wilson
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