Results 11 to 20 of about 93,083 (312)

High-Sensitive Cardiospecific Troponins: The Role of Gender-Specific Concentration in the Diagnosis of Acute Coronary Syndrome (Descriptive Review)

Reviews in Cardiovascular Medicine, 2023
Cardiospecific troponins are specifically localized in the troponin-tropomyosin complex and in the cytoplasm of cardiac myocytes. Cardiospecific troponin molecules are released from cardiac myocytes upon their death (irreversible damage in acute coronary
Aleksey Chaulin
doaj   +1 more source

Comprehensive Expression Analysis of Cardiac Fibroblast Growth Factor 23 in Health and Pressure-induced Cardiac Hypertrophy

Frontiers in Cell and Developmental Biology, 2022
Enhanced fibroblast growth factor 23 (FGF23) is associated with left ventricular hypertrophy (LVH) in patients with chronic kidney and heart disease. Experimentally, FGF23 directly induces cardiac hypertrophy and vice versa cardiac hypertrophy stimulates
Fiona Eitner, Beatrice Richter, Saskia Schwänen, Malgorzata Szaroszyk, Isabel Vogt, Andrea Grund, Thomas Thum, Joerg Heineke, Joerg Heineke, Dieter Haffner, Maren Leifheit-Nestler   +10 more
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Nuclear Calcium in Cardiac Myocytes [PDF]

Journal of Cardiovascular Pharmacology, 2015
Calcium (Ca) is a universal second messenger involved in the regulation of various cellular processes, including electrical signaling, contraction, secretion, memory, gene transcription, and cell death. In heart, Ca governs cardiomyocyte contraction, is central in electrophysiological properties, and controls major signaling pathway implicated in gene ...
Ljubojevic, Senka, Bers, Donald M
openaire   +4 more sources

Role of cation gradients in hypercontracture of myocytes during simulated ischemia and reperfusion [PDF]

, 1993
We examined the relationship between transsarcolemmal cation gradients and hypercontracture of cardiac myocytes in ischemia and reperfusion using adult rat ventricular myocytes superfused with buffer mimicking normal or ischemic extracellular fluid ...
J. P. Navas, Marsh, J. D., R. A. Kelly, J. D. Marsh, Krämer, Bernhard K., Kelly, R. A., Nishida, M., T. W. Smith, Smith, T. W., M. Nishida, B. Kraemer, Borzak, S., S. Borzak, Navas, J. P.   +13 more
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Deletion of Trpm4 Alters the Function of the Nav1.5 Channel in Murine Cardiac Myocytes. [PDF]

, 2021
Transient receptor potential melastatin member 4 (TRPM4) encodes a Ca2+-activated, non-selective cation channel that is functionally expressed in several tissues, including the heart.
Daniela Ross-Kaschitza, Prakash Arullampalam, Hugues Abriel, Essers, Maria C., Arullampalam, Prakash, Jean-Sébastien Rougier, Rougier, Jean-Sébastien, Lijo Cherian Ozhathil, Ozhathil, Lijo Cherian, Ross-Kaschitza, Daniela, Abriel, Hugues, Maria C. Essers   +11 more
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Subcellular heterogeneity of ryanodine receptor properties in ventricular myocytes with low T-tubule density [PDF]

, 2011
Rationale: In ventricular myocytes of large mammals, not all ryanodine receptor (RyR) clusters are associated with T-tubules (TTs); this fraction increases with cellular remodeling after myocardial infarction (MI).
MacQuaide, N., Bito, Virginie, Smith, G.L., Macquaide, Niall, Biesmans, L., Godfrey L. Smith, Frank R Heinzel, Sipido, Karin R., Karin R Sipido, Smith, Godfrey L., Rota, M., Heinzel, F.R., Godfrey L Smith, Bito, V., Sipido, K.R., Heinzel, Frank R., Niall Macquaide, Liesbeth Biesmans, Biesmans, Liesbeth, Virginie Bito, Frank R. Heinzel, Karin R. Sipido   +21 more
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Identification and characterization of insulin-like growth factor receptors on adult rat cardiac myocytes: linkage to inositol 1,4,5-trisphosphate formation. [PDF]

, 1992
Cultured cardiac myocytes from adult Sprague-Dawley rats express both insulin-like growth factor-I (IGF-I) receptors and insulin-like growth factor-II/mannose 6-phosphate (IGF-II/Man6P) receptors and respond to IGF-I with a dose-dependent accumulation of
Berg, Ingeborg, Guse, Andreas H., Kessler, Ulrike, Funk, Barbara, Gercken, Günther, A. H. Guse, Kiess, Wieland   +6 more
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Paracrine Effects of FGF23 on the Heart

Frontiers in Endocrinology, 2018
Fibroblast growth factor (FGF) 23 is a phosphaturic hormone primarily secreted by osteocytes to maintain phosphate and mineral homeostasis. In patients with and without chronic kidney disease, enhanced circulating FGF23 levels associate with pathologic ...
Maren Leifheit-Nestler, Dieter Haffner
doaj   +1 more source

Silibinin Protects Against Isoproterenol-Induced Rat Cardiac Myocyte Injury Through Mitochondrial Pathway After Up-regulation of SIRT1

Journal of Pharmacological Sciences, 2006
Terminally differentiated adult injured cardiac myocytes have been used for various animal models of heart failure. It has recently been shown that isoproterenol induces injury in rat neonatal cardiac myocytes via a β-adrenergic pathway, suggesting that ...
Bei Zhou, Li-Jun Wu, Lin-Hao Li, Shin-ichi Tashiro, Satoshi Onodera, Fumiaki Uchiumi, Takashi Ikejima   +6 more
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C-reactive protein inhibits survivin expression via Akt/mTOR pathway downregulation by PTEN expression in cardiac myocytes. [PDF]

PLoS ONE, 2014
C-reactive protein (CRP) is one of the most important biomarkers for arteriosclerosis and cardiovascular disease. Recent studies have shown that CRP affects cell cycle and inflammatory process in cardiac myocytes.
Beom Seob Lee, Soo Hyuk Kim, Jaewon Oh, Taewon Jin, Eun Young Choi, Sungha Park, Sang-Hak Lee, Ji Hyung Chung, Seok-Min Kang   +8 more
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