Results 21 to 30 of about 81,793 (267)
BMC Cell Biology, 2012 Background Hyperleptinemia is known to participate in cardiac hypertrophy and hypertension, but the relationship between pressure overload and leptin is poorly understood. We therefore examined the expression of leptin (ob) and the leptin receptor (ob-R)
Matsui Hiroki +7 more
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The Hippo pathway regulates density-dependent proliferation of iPSC-derived cardiac myocytes
Scientific Reports, 2021 Inducing cardiac myocytes to proliferate is considered a potential therapy to target heart disease, however, modulating cardiac myocyte proliferation has proven to be a technical challenge.
Abigail C. Neininger +3 more
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Journal of Pharmacological Sciences, 2008 It has been suggested that a new type of large-conductance Ca2+-activated K+ (BK) channel is distributed in the inner mitochondrial membrane (mitoKCa channel) and that its opening may attenuate ischemic cardiac injury.
Kazuho Sakamoto +3 more
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Polyploidization of transplanted cardiac myocytes [PDF]
Cell Differentiation and Development, 1988 Pieces of cardiac ventricular tissue of late embryonic or 1-day postnatal rats, implanted beneath the kidney capsule of adult syngeneic hosts, formed viable, beating transplants. These transplants were investigated over a 40-day postoperative course. In the transplants, cellular binucleation and nuclear polyploidization occurred according to the same ...
Brodsky, V. Ya. +3 more
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Epigenetic regulation of cardiac myocyte differentiation†[PDF]
Frontiers in Genetics, 2014 Cardiac myocytes (CMs) proliferate robustly during fetal life but withdraw permanently from the cell cycle soon after birth and undergo terminal differentiation. This cell cycle exit is associated with the upregulation of a host of adult cardiac-specific genes.
Oyama, Kyohei +4 more
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Alexandria Journal of Medicine, 2016 The calcium signaling plays a crucial role in expansion and contraction of cardiac myocytes. This calcium signaling is achieved by calcium diffusion, buffering mechanisms and influx in cardiac myocytes.
Kunal Pathak, Neeru Adlakha
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Cellular Physiology of Rat Cardiac Myocytes in Cardiac Fibrosis: In Vitro Simulation Using the Cardiac Myocyte/Cardiac Non-Myocyte Co-Culture System [PDF]
Hypertension Research, 2008 An understanding of the cellular physiology of cardiac myocytes (MCs) and non-myocytes (NMCs) may help to explain the mechanisms underlying cardiac hypertrophy. Despite numerous studies using MC/NMC co-culture systems, it is difficult to precisely evaluate the influence of each cell type because of the inherent cellular heterogeneity of such a system ...
Keiichi, Ikeda +9 more
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The Unmasking Effect: Propofol-Induced Brugada Pattern in a Critically Ill Patient
Case Reports in Cardiology, 2022 Brugada syndrome is a known cause of dysrhythmias and sudden cardiac death. It is linked to mutations in myocardial sodium channel leading to hyperexcitable cardiac myocytes.
Esiemoghie Akhigbe +4 more
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Gene Transfer into Cardiac Myocytes [PDF]
, 2015 Traditional methods for DNA transfection are often inefficient and toxic for terminally differentiated cells, such as cardiac myocytes. Vector-based gene transfer is an efficient approach for introducing exogenous cDNA into these types of primary cell cultures.
Sarah E, Lang, Margaret V, Westfall
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Antioxidants, 2021 To investigate the role of NLRP3 inflammasome in cardiac aging, we evaluate here morphological and ultrastructural age-related changes of cardiac muscles fibers in wild-type and NLRP3-knockout mice, as well as studying the beneficial effect of melatonin ...
Ramy K. A. Sayed +9 more
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