Results 161 to 170 of about 1,444,670 (278)

Goal-Directed Versus Self-Directed Valsalva Maneuver in Patients With Hypertrophic Cardiomyopathy on Cardiac Myosin Inhibitor Therapy. [PDF]

JACC Adv
Bavishi A, Soutar M, Kurnides M, Speer H, Oyarce G, Bryde R, Lander B, Richards K, DeMarco K, Martinez MW.   +9 more
europepmc   +1 more source

Cardiac myosin inhibitors in hypertrophic cardiomyopathy: advancing care with caution

Annals of Medicine & Surgery
Zoya Rehman, Faisal Ahsaan, Bakhtawar Latif, Ahmad Furqan Anjum, Hermann Yokolo   +4 more
openaire   +2 more sources

Channelrhodopsin ion selectivity determines mechanisms and efficacy of optogenetic defibrillation in human atria and ventricles

The Journal of Physiology, EarlyView.
Abstract figure legend A, we used in silico models of human cardiomyocytes and microelectrode recordings on transgenic zebrafish hearts to study electrophysiology during optogenetic perturbations. Specifically, we compared effects of three distinct classes of channelrhodopsins: the cation non‐selective Chlamydomonas reinhardtii channelrhodopsin‐2 (ChR2)
Sophia Ohnemus, Albert Dasí, Ahmed F. Ramadan, Joachim Greiner, Eike M. Wülfers, Matthew R. Stoyek, Linda Tillert, Johannes Vierock, T. Alexander Quinn, Peter Kohl, Patrick M. Boyle, Viviane Timmermann, Franziska Schneider‐Warme   +12 more
wiley   +1 more source

Comparative proteomic analysis of bone marrow mononuclear cells and peripheral blood mononuclear cells for autologous therapeutic implantation in chronic wounds

Clinical and Translational Discovery, Volume 6, Issue 6, December 2026.
• Integrative evaluation with proteomic analysis of mononuclear cells (MNC) from bone marrow (BM) or peripheral blood (PB) sources for autologous cell implantation in patients with chronic wounds sheds light on molecular differences and clinical outcomes. • BM‐MNC and PB‐MNC exhibited distinct and source‐specific proteomic signatures.
Farina Mohamad Yusoff, Nor Azfa Johari, Masato Kajikawa, Sharifah Zakiah Syed Sulaiman, Harikrishna K R Nair, Sze‐Piaw Chin, Shinji Kishimoto, Tatsuya Maruhashi, S Fadilah S Abdul Wahid, Yukihito Higashi   +9 more
wiley   +1 more source

Multiparametric cardiovascular magnetic resonance evaluation of myocardial perfusion, oxygenation, and energetics in hypertrophic cardiomyopathy following cardiac myosin inhibitor therapy. [PDF]

Eur Heart J Cardiovasc Imaging
Finnigan LEM, Beyhoff N, Ashkir Z, Watkins H, Neubauer S, Raman B.   +5 more
europepmc   +1 more source

Endotoxins and Biological Implications—Review

Public Health Challenges, Volume 5, Issue 4, December 2026.
Graphical overview of endotoxin sources, exposure routes, biological effects, detection methods, and routes of elimination. ABSTRACT Endotoxins, also known as lipopolysaccharides (LPSs), are structural components of the outer membrane of Gram‐negative bacteria and some cyanobacteria.
Uzair Ishtiaq, Nicolas Joly, Vincent Lequart, Patrick Martin, Marielba Morillo, Janne Rojas   +5 more
wiley   +1 more source

Further Insights Into the Mechanisms of Lymph Node Metastasis

Cancer Medicine, Volume 15, Issue 11, November 2026.
ABSTRACT Metastasis of malignant tumors arising from epithelial organs to sentinel lymph nodes has important implications for prognosis, staging, and therapeutic decision‐making. Recent insights into anatomic pathways, pathogenesis, molecular interactions, and genetic factors have encouraged scientists and clinicians to develop drugs that target ...
S. David Nathanson, Meghan J. O'Melia, Kelly C. Rosso, Ian S. Wood, Drishti Lall, Jenny T. Bui   +5 more
wiley   +1 more source

Quercetin and Cardiovascular Health: An Evidence‐Based Review of Risk Factors and Treatments

Food Science &Nutrition, Volume 14, Issue 11, November 2026.
Quercetin is a naturally occurring polyphenolic phytochemical distributed in fruits and vegetables. Quercetin, as a flavonoid, showed significant antioxidant capabilities and potential therapeutic effects on CVD risk factors. Quercetin reduces cardiac hypertrophy and apoptosis in cardiomyocytes by modulating critical signaling pathways.
Mohammad Reza Khazdair, Shima Jafari, Melika Shoghi   +2 more
wiley   +1 more source

Neointimal Hyperplasia and Restenosis: Epidemiology, Pathophysiology, Animal Models, Clinical Features, Diagnosis, and Management

MedComm, Volume 7, Issue 11, November 2026.
The overall graphical diagram to summarize the pathological characteristics, pathogenesis, clinical manifestation, preclinical animal models, diagnostic methods, and intervention strategies for neointimal hyperplasia. Neointimal hyperplasia results from excessive proliferation and intimal migration of vascular smooth muscle cells (VSMCs) in the ...
Kaixu Wang, Daiyu Zhang, Yu Hu, Yixin Zhao, Xinling Wang, Long Jiang, Meixiu Jiang   +6 more
wiley   +1 more source

Structure-Function Relationship as the Foundation for Cardiac Myosin Inhibition in Hypertrophic Cardiomyopathy. [PDF]

Circulation
Kawana M, Ruppel KM, Spudich JA.
europepmc   +1 more source