Results 11 to 20 of about 1,084,670 (306)

Endurance Training Regulates Expression of Some Angiogenesis-Related Genes in Cardiac Tissue of Experimentally Induced Diabetic Rats

Biomolecules, 2021
Exercise can ameliorate cardiovascular dysfunctions in the diabetes condition, but its precise molecular mechanisms have not been entirely understood.
Mojdeh Khajehlandi, Lotfali Bolboli, Marefat Siahkuhian, Mohammad Rami, Mohammadreza Tabandeh, Kayvan Khoramipour, Katsuhiko Suzuki   +6 more
doaj   +1 more source

The Curie effect incorporation in the monodomain equation describing the action potential dynamics in cardiac tissue [PDF]

INCAS Bulletin, 2023
In their in-depth study on cardiac tissue modeling, Clayton and Panfilov [1] present several monodomain or bidomain approaches for the mathematical description of the cardiac tissue action potential dynamics.
Agneta M. BALINT, Stefan BALINT, Adrian NECULAE   +2 more
doaj   +1 more source

EM-mosaic detects mosaic point mutations that contribute to congenital heart disease. [PDF]

, 2020
BackgroundThe contribution of somatic mosaicism, or genetic mutations arising after oocyte fertilization, to congenital heart disease (CHD) is not well understood.
Bernstein, Daniel, Brueckner, Martina, Chung, Wendy K, DePalma, Steven, Gelb, Bruce D, Goldmuntz, Elizabeth, Gorham, Joshua M, Griffin, Emily, Hsieh, Alexander, Kim, Richard W, Lifton, Richard P, Manheimer, Kathryn B, McKean, David, Morton, Sarah U, Newburger, Jane W, Porter, George A, Qi, Hongjian, Seidman, Christine E, Seidman, JG, Shen, Yufeng, Srivastava, Deepak, Tai, Angela C, Tristani-Firouzi, Martin, Willcox, Jon AL   +23 more
core   +3 more sources

Electroactive Polymeric Composites to Mimic the Electromechanical Properties of Myocardium in Cardiac Tissue Repair

Gels, 2021
Due to the limited regenerative capabilities of cardiomyocytes, incidents of myocardial infarction can cause permanent damage to native myocardium through the formation of acellular, non-conductive scar tissue during wound repair.
Kaylee Meyers, Bruce P. Lee, Rupak M. Rajachar   +2 more
doaj   +1 more source

Antioxidant Activity of Vitamin C against LPS-Induced Septic Cardiomyopathy by Down-Regulation of Oxidative Stress and Inflammation

Current Issues in Molecular Biology, 2022
In severe cases of sepsis, endotoxin-induced cardiomyopathy can cause major damage to the heart. This study was designed to see if Vitamin C (Vit C) could prevent lipopolysaccharide-induced heart damage.
Ayed A. Shati, Mohamed Samir A. Zaki, Youssef A. Alqahtani, Saleh M. Al-Qahtani, Mohamed A. Haidara, Amal F. Dawood, Asmaa M. AlMohanna, Mahmoud H. El-Bidawy, Muhammad Alaa Eldeen, Refaat A. Eid   +9 more
doaj   +1 more source

Engineering virtual cardiac tissue [PDF]

Briefings in Bioinformatics, 2001
The kinetics of proteins involved in ion transfer, sequestration and binding in cardiac cells can be modelled to construct a model of the electrical activity of isolated cardiac cells as a system of ordinary differential equations. These cell models may be incorporated into tissue models, which, when combined with histology and anatomy, form virtual ...
Boyett, M. R., Holden, A. V., Zhang, H.
openaire   +3 more sources

Cardiac tissue engineering

Transplant Immunology, 2002
Recent progress in implantations of differentiated cardiac and non-cardiac cells as well as adult stem cells into the heart suggests that the irreversible loss of viable cardiac myocytes that occurs during myocardial infarction can be at least partly substituted.
Eschenhagen, Thomas, Didie, Michael, Heubach, J., Ravens, U., Zimmermann, Wolfram-Hubertus   +4 more
openaire   +5 more sources

Galangin Attenuates Isoproterenol-Induced Inflammation and Fibrosis in the Cardiac Tissue of Albino Wistar Rats

Frontiers in Pharmacology, 2020
Galangin (GA) is an active flavonoid of the rhizome of Alpinia galanga that belongs to the ginger family. GA exhibit potent anti-inflammatory properties.
Radhiga Thangaiyan, Sundaresan Arjunan, Kanimozhi Govindasamy, Haseeb A. Khan, Abdullah S. Alhomida, Nagarajan Rajendra Prasad   +5 more
doaj   +1 more source

Living myocardial slices for the study of nucleic acid-based therapies

Frontiers in Bioengineering and Biotechnology, 2023
Gene therapy based on viral vectors offers great potential for the study and the treatment of cardiac diseases. Here we explore the use of Living Myocardial Slices (LMS) as a platform for nucleic acid-based therapies. Rat LMS and Adeno-Associated viruses
R. Nunez-Toldra, A. Del Canizo, I. Secco, L. Nicastro, M. Giacca, C. M. Terracciano   +5 more
doaj   +1 more source

Functional Cardiac Tissue Engineering [PDF]

Regenerative Medicine, 2012
Heart attack remains the leading cause of death in both men and women worldwide. Stem cell-based therapies, including the use of engineered cardiac tissues, have the potential to treat the massive cell loss and pathological remodeling resulting from heart attack.
Brian, Liau, Donghui, Zhang, Nenad, Bursac   +2 more
openaire   +2 more sources