Results 11 to 20 of about 1,102,241 (353)
Cardiac tissue engineering [PDF]
Journal of the Serbian Chemical Society, 2005 We hypothesized that clinically sized (1-5 mm thick),compact cardiac constructs containing physiologically high density of viable cells (≈108 cells/cm3) can be engineered in vitro by using biomimetic culture systems capable of providing oxygen transport ...
Radišić Milica +1 more
doaj +5 more sources
Engineered cardiac tissues [PDF]
Current Opinion in Biotechnology, 2011 Cardiac tissue engineering offers the promise of creating functional tissue replacements for use in the failing heart or for in vitro drug screening. The last decade has seen a great deal of progress in this field with new advances in interdisciplinary areas such as developmental biology, genetic engineering, biomaterials, polymer science, bioreactor ...
Rohin K, Iyer +3 more
openaire +2 more sources
Cardiac Tissue Engineering [PDF]
Journal of Cardiovascular Nursing, 2009 The first 2 reviews in this series have described the defining properties of stem cells, their possible sources, and some initial attempts at their clinical use for tissue regeneration and repair. This third and final article in the series describes bioengineering methods for building physical structures to contain and organize implanted cells.
Matthew W, Curtis, Brenda, Russell
openaire +2 more sources
Gels, 2021 Due to the limited regenerative capabilities of cardiomyocytes, incidents of myocardial infarction can cause permanent damage to native myocardium through the formation of acellular, non-conductive scar tissue during wound repair.
Kaylee Meyers +2 more
doaj +1 more source
EM-mosaic detects mosaic point mutations that contribute to congenital heart disease. [PDF]
, 2020 BackgroundThe contribution of somatic mosaicism, or genetic mutations arising after oocyte fertilization, to congenital heart disease (CHD) is not well understood.
Bernstein, Daniel +23 more
core +3 more sources
Current Issues in Molecular Biology, 2022 In severe cases of sepsis, endotoxin-induced cardiomyopathy can cause major damage to the heart. This study was designed to see if Vitamin C (Vit C) could prevent lipopolysaccharide-induced heart damage.
Ayed A. Shati +9 more
doaj +1 more source
Engineering virtual cardiac tissue [PDF]
Briefings in Bioinformatics, 2001 The kinetics of proteins involved in ion transfer, sequestration and binding in cardiac cells can be modelled to construct a model of the electrical activity of isolated cardiac cells as a system of ordinary differential equations. These cell models may be incorporated into tissue models, which, when combined with histology and anatomy, form virtual ...
Boyett, M. R., Holden, A. V., Zhang, H.
openaire +3 more sources
Transplant Immunology, 2002 Recent progress in implantations of differentiated cardiac and non-cardiac cells as well as adult stem cells into the heart suggests that the irreversible loss of viable cardiac myocytes that occurs during myocardial infarction can be at least partly substituted.
Eschenhagen, Thomas +4 more
openaire +5 more sources
Frontiers in Pharmacology, 2020 Galangin (GA) is an active flavonoid of the rhizome of Alpinia galanga that belongs to the ginger family. GA exhibit potent anti-inflammatory properties.
Radhiga Thangaiyan +5 more
doaj +1 more source
Living myocardial slices for the study of nucleic acid-based therapies
Frontiers in Bioengineering and Biotechnology, 2023 Gene therapy based on viral vectors offers great potential for the study and the treatment of cardiac diseases. Here we explore the use of Living Myocardial Slices (LMS) as a platform for nucleic acid-based therapies. Rat LMS and Adeno-Associated viruses
R. Nunez-Toldra +5 more
doaj +1 more source