Results 31 to 40 of about 719,635 (266)

Multidimensional Regulation of Cardiac Mitochondrial Potassium Channels

open access: yesCells, 2021
Mitochondria play a fundamental role in the energetics of cardiac cells. Moreover, mitochondria are involved in cardiac ischemia/reperfusion injury by opening the mitochondrial permeability transition pore which is the major cause of cell death.
Bogusz Kulawiak   +2 more
doaj   +1 more source

Engineered Human Cardiac Tissue [PDF]

open access: yesPediatric Cardiology, 2011
The human heart is the first organ to develop during embryogenesis and is arguably the most essential organ for life. However, after birth, the heart has very little capacity to repair malformations such as congenital heart defects or to regenerate after an injury such as myocardial infarction.
Kareen L, Kreutziger, Charles E, Murry
openaire   +2 more sources

A chromEM-staining protocol optimized for cardiac tissue

open access: yesFrontiers in Cell and Developmental Biology, 2023
Three-dimensional (3D) chromatin organization has a key role in defining the transcription program of cells during development. Its alteration is the cause of gene expression changes responsible for several diseases. Thus, we need new tools to study this
Elettra Musolino   +9 more
doaj   +1 more source

Tissue Characterization in Cardiac Amyloidosis

open access: yesBiomedicines, 2022
Cardiac amyloidosis (CA) has long been considered a rare disease, but recent advancements in diagnostic tools have led to a reconsideration of the epidemiology of CA. Amyloid light-chain (AL) and transthyretin (ATTR) amyloidoses are the most common forms of cardiac amyloidosis.
Veronica Musetti   +10 more
openaire   +4 more sources

Natural biomaterials in the management of the aortic valve pathology. Biomedical and clinical aspects: A review

open access: yesBiomolecules & Biomedicine
Heart valve diseases are a prevalent cardiovascular pathology worldwide, affecting nearly 2.5% of the population. Degenerative aortic stenosis is the most common form of heart valve disease.
Igor Mokryk   +5 more
doaj   +1 more source

Heterocellularity and Cellular Cross-Talk in the Cardiovascular System

open access: yesFrontiers in Cardiovascular Medicine, 2018
Cellular specialization and interactions with other cell types are the essence of complex multicellular life. The orchestrated function of different cell populations in the heart, in combination with a complex network of intercellular circuits of ...
Filippo Perbellini   +3 more
doaj   +1 more source

NMR-Based Metabolomic Analysis of Cardiac Tissues Clarifies Molecular Mechanisms of CVB3-Induced Viral Myocarditis and Dilated Cardiomyopathy

open access: yesMolecules, 2022
Viral myocarditis (VMC), which is defined as inflammation of the myocardium with consequent myocardial injury, may develop chronic disease eventually leading to dilated cardiomyopathy (DCM). Molecular mechanisms underlying the progression from acute VMC (
Qing Kong   +6 more
doaj   +1 more source

Cardiac Tissue Engineering [PDF]

open access: yesCirculation Research, 2014
The engineering of 3-dimensional (3D) heart muscles has undergone exciting progress for the past decade. Profound advances in human stem cell biology and technology, tissue engineering and material sciences, as well as prevascularization and in vitro assay technologies make the first clinical application of engineered cardiac tissues a realistic option
Marc N, Hirt   +2 more
openaire   +2 more sources

Pathological Structural Alterations of Serous Cell Cilia in the Parietal Pericardium of Patients With Heart Failure Induced by Dilated Cardiomyopathy

open access: yesReviews in Cardiovascular Medicine
Background: This study aimed to examine pathological surface structural changes in serous cells of the pericardial parietal layer in patients with heart failure due to dilated cardiomyopathy.
Yingtian Liu   +7 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

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