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Cardiac tissue engineering [PDF]
Journal of the Serbian Chemical Society, 2005 We hypothesized that clinically sized (1-5 mm thick),compact cardiac constructs containing physiologically high density of viable cells (≈108 cells/cm3) can be engineered in vitro by using biomimetic culture systems capable of providing oxygen transport ...
Radišić Milica +1 more
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Engineered cardiac tissues [PDF]
Current Opinion in Biotechnology, 2011 Cardiac tissue engineering offers the promise of creating functional tissue replacements for use in the failing heart or for in vitro drug screening. The last decade has seen a great deal of progress in this field with new advances in interdisciplinary areas such as developmental biology, genetic engineering, biomaterials, polymer science, bioreactor ...
Rohin K, Iyer +3 more
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Cardiac Tissue Engineering [PDF]
Journal of Cardiovascular Nursing, 2009 The first 2 reviews in this series have described the defining properties of stem cells, their possible sources, and some initial attempts at their clinical use for tissue regeneration and repair. This third and final article in the series describes bioengineering methods for building physical structures to contain and organize implanted cells.
Matthew W, Curtis, Brenda, Russell
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Engineering virtual cardiac tissue [PDF]
Briefings in Bioinformatics, 2001 The kinetics of proteins involved in ion transfer, sequestration and binding in cardiac cells can be modelled to construct a model of the electrical activity of isolated cardiac cells as a system of ordinary differential equations. These cell models may be incorporated into tissue models, which, when combined with histology and anatomy, form virtual ...
Boyett, M. R., Holden, A. V., Zhang, H.
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Advances in Cardiac Tissue Engineering
Bioengineering, 2022 Tissue engineering has paved the way for the development of artificial human cardiac muscle patches (hCMPs) and cardiac tissue analogs, especially for treating Myocardial infarction (MI), often by increasing its regenerative abilities. Low engraftment rates, insufficient clinical application scalability, and the creation of a functional vascular system
Takahiro Kitsuka +7 more
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Current Issues in Molecular Biology, 2022 In severe cases of sepsis, endotoxin-induced cardiomyopathy can cause major damage to the heart. This study was designed to see if Vitamin C (Vit C) could prevent lipopolysaccharide-induced heart damage.
Ayed A. Shati +9 more
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Frontiers in Pharmacology, 2020 Galangin (GA) is an active flavonoid of the rhizome of Alpinia galanga that belongs to the ginger family. GA exhibit potent anti-inflammatory properties.
Radhiga Thangaiyan +5 more
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Living myocardial slices for the study of nucleic acid-based therapies
Frontiers in Bioengineering and Biotechnology, 2023 Gene therapy based on viral vectors offers great potential for the study and the treatment of cardiac diseases. Here we explore the use of Living Myocardial Slices (LMS) as a platform for nucleic acid-based therapies. Rat LMS and Adeno-Associated viruses
R. Nunez-Toldra +5 more
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Indentation of Anisotropic Tissue Using a Three-Dimensional Mechanical Bidomain Model
Fibers, 2022 Computation-based mathematical models of tissue indentation are capable of predicting the distribution of forces and mechanical properties of soft tissues.
Dilmini Wijesinghe, Bradley J. Roth
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Nanomaterials for Cardiac Tissue Engineering [PDF]
Molecules, 2020 End stage heart failure is a major cause of death in the US. At present, organ transplant and left-ventricular assist devices remain the only viable treatments for these patients. Cardiac tissue engineering presents the possibility of a new option. Nanomaterials such as gold nanorods (AuNRs) and carbon nanotubes (CNTs) present unique properties that ...
Devang R. Amin +5 more
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