Results 71 to 80 of about 1,102,241 (353)

Recent advances in biological pumps as a building block for bioartificial hearts

Frontiers in Bioengineering and Biotechnology, 2023
The field of biological pumps is a subset of cardiac tissue engineering and focused on the development of tubular grafts that are designed generate intraluminal pressure.
Sunita Brimmer, Sunita Brimmer, Sunita Brimmer, Pengfei Ji, Pengfei Ji, Pengfei Ji, Aditya K. Birla, Aditya K. Birla, Sundeep G. Keswani, Sundeep G. Keswani, Sundeep G. Keswani, Sundeep G. Keswani, Christopher A. Caldarone, Christopher A. Caldarone, Christopher A. Caldarone, Christopher A. Caldarone, Ravi K. Birla, Ravi K. Birla, Ravi K. Birla, Ravi K. Birla, Ravi K. Birla   +20 more
doaj   +1 more source

Myocardial aging as a T-cell–mediated phenomenon [PDF]

, 2017
In recent years, the myocardium has been rediscovered under the lenses of immunology, and lymphocytes have been implicated in the pathogenesis of cardiomyopathies with different etiologies.
Abeßer, Marco, Beyersdorf, Niklas, Burkard, Matthias, Frantz, Stefan, Friedrich, Mike, Heinze, Katrin G., Hofmann, Ulrich, Jocelyne, Demengeot, Kerkau, Thomas, Nunes-Silva, Vânia, Peters, Laura, Pinnecker, Jürgen, Ramos, Gustavo Campos, Schuh, Kai, van den Berg, Anne, Weirather, Johannes   +15 more
core   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Machine learning to predict overall short-term mortality in cutaneous melanoma

Discover Oncology, 2023
Background Cutaneous malignant melanoma (CMM) ranks among the ten most frequent malignancies, clinicopathological staging being of key importance to predict prognosis.
C. Cozzolino, A. Buja, M. Rugge, A. Miatton, M. Zorzi, A. Vecchiato, P. Del Fiore, S. Tropea, A. Brazzale, G. Damiani, L. dall’Olmo, C. R. Rossi, S. Mocellin   +12 more
doaj   +1 more source

Recapitulating Cardiac Structure and Function In Vitro from Simple to Complex Engineering

Micromachines, 2021
Cardiac tissue engineering aims to generate in vivo-like functional tissue for the study of cardiac development, homeostasis, and regeneration.
Ana Rita M. P. Santos, Yongjun Jang, Inwoo Son, Jongseong Kim, Yongdoo Park   +4 more
doaj   +1 more source

Metabolic reprogramming of murine cardiomyocytes during autophagy requires the extracellular nutrient sensor decorin. [PDF]

, 2018
The extracellular matrix is a master regulator of tissue homeostasis in health and disease. Here we examined how the small, leucine-rich, extracellular matrix proteoglycan decorin regulates cardiomyocyte metabolism during fasting in vivo.
Gubbiotti, Maria A., Hoek, Jan B., Iozzo, Renato V., Rodeck, Ulrich, Seifert, Erin L.   +4 more
core   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

ANALYSIS OF COLLAGEN PRODUCTION IN HYPERTROPHIC CARDIAC TISSUE OF RATS TREATED WITH L-NAME AND L-ARGININE BY IMAGE PROCESSING

Revista UniVap, 2019
We analyzed the production of collagen in the heart of hypertensive rats induced by L-name. Methods: Cardiac imaging of 5 groups: NT, hypertension induced by L-name, L-name and 10 mg L-arginine, L-name and 30 mg L-arginine and L-name and 100 mg L ...
Vanessa Oliveira Colombo Marson, Márcia Aparecida Silva Bissaco, Luciano Ramos, Silvia Cristina Martini Rodrigues, Romildo Torres Da Silva, Fernando Francisco Pazello Mafra, Michel Monteiro Macedo, Patrícia Sardinha Leonardo Lopes Martins, Rodrigo Alvaro Brandão Lopes Martins   +8 more
doaj   +1 more source

Interconnection between Cardiac Cachexia and Heart Failure—Protective Role of Cardiac Obesity

Cells, 2022
Cachexia may be caused by congestive heart failure, and it is then called cardiac cachexia, which leads to increased morbidity and mortality. Cardiac cachexia also worsens skeletal muscle degradation.
María Elena Soto, Israel Pérez-Torres, María Esther Rubio-Ruiz, Linaloe Manzano-Pech, Verónica Guarner-Lans   +4 more
doaj   +1 more source

Ventricular androgenic-anabolic steroid-related remodeling: an immunohistochemical study [PDF]

, 2017
Background: Several fatal cases of bodybuilders, following a myocardial infarction after long exposure to androgenicanabolic steroids (AAS), are reported. In recent years, evidence has emerged of cases of heart failure related to AAS consumption, with no
Cecchi, Rossana, Ciallella, Costantino, DI LUCA, Natale Mario, Kimura, Akihiko, Kondo, Toshikazu, Muciaccia, Barbara, Nosaka, Mizuho, Sestili, Cristina   +7 more
core   +1 more source