Results 191 to 200 of about 7,413,990 (275)

Bio-orthogonally double cross-linked alginate-gelatin hydrogels with tunable viscoelasticity for cardiac tissue engineering. [PDF]

Mater Today Bio
Testore D, Zoso A, Paoletti C, Groppo S, Marcello E, Chiono V.   +5 more
europepmc   +1 more source

Mechanical Characterization of 3D-Printed Patterned Membranes for Cardiac Tissue Engineering: An Experimental and Numerical Study. [PDF]

Biomedicines, 2023
Poerio A, Guibert B, Leroux MM, Mano JF, Cleymand F, Jehl JP.   +5 more
europepmc   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

Advanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang, Zijian Zhang, Fulin Dai, Zhijie Yin, Zhen Xing, Yurong Li, Haochong Lei, Junfeng Zhang, Chunyan Liu, Yan Li, Lei Dong   +10 more
wiley   +1 more source

Advances in Conductive Biomaterials for Cardiac Tissue Engineering: Design, Fabrication, and Functional Integration. [PDF]

Polymers (Basel)
Khan T, Vadivel G, Ayyasamy K, Murugesan G, Sebaey TA.   +4 more
europepmc   +1 more source

KLF5 Downregulation Links Impaired BNIP3‐Mediated Mitophagy to Inflammatory Valve Remodeling in Calcific Aortic Valve Disease

Advanced Science, EarlyView.
In human CAVD, KLF5 is reduced in VIC‐rich regions and remodeling/stress‐associated VIC states. In VICs, KLF5 sustains BNIP3 promoter activity and BNIP3‐mediated mitophagy, thereby limiting cytosolic mtDNA accumulation. KLF5 loss weakens mitochondrial quality control and enhances mtDNA‐sensitive STING/NF‐κB/NLRP3 inflammatory signaling under osteogenic
Jin‐Hui Bian, Jia‐Xi Gu, Zhang Yue, Chun‐Ze Yuan, Hai‐Bin Ji, Ao Li, Yu Zhong, Xiu‐Fan Xu, Yu‐Qiu He, Ye‐Fan Jiang, Hong‐Shan Chen, Xiang Chen, Meng‐Lin Chao, Yong‐Feng Shao   +13 more
wiley   +1 more source

A novel biomimetic nanofibrous cardiac tissue engineering scaffold with adjustable mechanical and electrical properties based on poly(glycerol sebacate) and polyaniline. [PDF]

Mater Today Bio, 2023
Wu Z, Li Q, Wang L, Zhang Y, Liu W, Zhao S, Geng X, Fan Y.   +7 more
europepmc   +1 more source

Modular Metamaterials for Adaptable MRI Signal Control: Combining Dipole Array With a New Hexagon‐Based Artificial Dielectrics

Advanced Science, EarlyView.
A flexible, hexagonally packed artificial dielectric providing a wide range of effective permittivities (εr ≈ 30–1400) without lumped elements was developed for clinical and ultra‐high‐field MRI. Combined with modular passive‐dipole arrays, the system enables adaptable RF field shaping through electric‐ and magnetic‐dipole tuning.
Santosh Kumar Maurya, Ilan Goldberg, Rita Schmidt   +2 more
wiley   +1 more source

Bioprinting approaches in cardiac tissue engineering to reproduce blood-pumping heart function. [PDF]

iScience
Kim M, Hwang DG, Jang J.
europepmc   +1 more source

Versatile electrical stimulator for cardiac tissue engineering-Investigation of charge-balanced monophasic and biphasic electrical stimulations. [PDF]

Front Bioeng Biotechnol, 2022
Gabetti S, Sileo A, Montrone F, Putame G, Audenino AL, Marsano A, Massai D.   +6 more
europepmc   +1 more source

SerpinA3 is an Endogenous TGF‐β Receptor Antagonist that Attenuates Cardiac Fibroblast Activation and Fibrotic Remodeling

Advanced Science, EarlyView.
SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang, Jieyu Cui, Chunlu Huang, Wanyi Guo, Tong Liu, Yi Zhu, Shuai Shao, Kangyin Chen, Jinlong He, Qiankun Bao   +9 more
wiley   +1 more source