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Recent Patents on Regenerative Medicinee, 2011
This book chapter will explore the area of cardiac tissue engineering and biomaterials used for cardiac cell therapy. After describing the pathology of heart disease and presenting the motivation for pursuing tissue engineering for the heart, the chapter outlines some of the current clinical treatments used to correct the loss of function resulting ...
Devang Odedra +5 more
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This book chapter will explore the area of cardiac tissue engineering and biomaterials used for cardiac cell therapy. After describing the pathology of heart disease and presenting the motivation for pursuing tissue engineering for the heart, the chapter outlines some of the current clinical treatments used to correct the loss of function resulting ...
Devang Odedra +5 more
+5 more sources
Cardiac Tissue Engineering on the Nanoscale
ACS Biomaterials Science & Engineering, 2018In recent years, the fabrication of smart materials at an arbitrary gauge has attracted enormous interest from researchers in the tissue engineering (TE) field. This potential tool has been utilized for the generation of various biomimetic/bioinspired structures to repair and improve the performance of the injured tissues.
Ranjith Kumar Kankala +5 more
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Bioreactors for Cardiac Tissue Engineering
Advanced Healthcare Materials, 2018AbstractThe advances in biotechnology, biomechanics, and biomaterials can be used to develop organ models that aim to accurately emulate their natural counterparts. Heart disease, one of the leading causes of death in modern society, has attracted particular attention in the field of tissue engineering.
Jesus Paez‐Mayorga +7 more
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Engineering Cardiac Muscle Tissue
Circulation Research, 2017 Twenty years after the initial description of a tissue engineered construct, 3-dimensional human cardiac tissues of different kinds are now generated routinely in many laboratories.
Florian Weinberger +2 more
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Strategies in cardiac tissue engineering
ANZ Journal of Surgery, 2010AbstractIn heart failure, post‐myocardial infarction and some congenital cardiac anomalies, organ transplantation is the only effective cure. Shortage of organ donors and complications of orthotopic heart transplant remain major challenges to the modern field of transplantation.
Richard, Tee +3 more
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On Materials for Cardiac Tissue Engineering
Advanced Healthcare Materials, 2016In this essay the authors argue that chamber pressure dominates the biomechanics of the contraction cycle of the heart, while tissue stiffness dominates the relaxation cycle. This appears to be an under-recognized challenge in cardiac tissue engineering.
Ibrahim J, Domian +2 more
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Tissue-Engineered Cardiac Constructs for Cardiac Repair
The Annals of Thoracic Surgery, 2011Several recent basic research studies have described surgical methods for cardiac repair using tissue cardiomyoplasty. This review summarizes recent advances in cardiac repair using bioengineered tissue from the viewpoint of the cardiac surgeon. We conclude that the results of many basic and preclinical studies indicate that bioengineered tissue can be
Shigeru, Miyagawa +4 more
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Cardiac muscle tissue engineering
IEEE Engineering in Medicine and Biology Magazine, 2003Cell-based therapy has emerged as a novel approach for replacing heart muscle, which is known not to regenerate after injury such as that caused by infarction or reconstructive surgery. Two types of cell-based therapies have been employed: injection of isolated cells or the implantation of in-vitro-grown cardiac muscle tissue equivalents In the first ...
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Scaffolds for tissue engineering of cardiac valves
Acta Biomaterialia, 2014Tissue engineered heart valves offer a promising alternative for the replacement of diseased heart valves avoiding the limitations faced with currently available bioprosthetic and mechanical heart valves. In the paradigm of tissue engineering, a three-dimensional platform - the so-called scaffold - is essential for cell proliferation, growth and ...
S, Jana +3 more
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Fibrin as a scaffold for cardiac tissue engineering
Biotechnology and Applied Biochemistry, 2011AbstractFibrin is a natural biopolymer with many interesting properties, such as biocompatibility, bioresorbability, ease of processing, ability to be tailored to modify the conditions of polymerization, and potential for incorporation of both cells and cell mediators.
Barsotti MC +3 more
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