Results 71 to 80 of about 273,643 (353)

Elevated Plasma Cardiac Troponin T Levels Caused by Skeletal Muscle Damage in Pompe Disease

Circulation: Cardiovascular Genetics, 2016
Background—Elevated plasma cardiac troponin T (cTnT) levels in patients with neuromuscular disorders may erroneously lead to the diagnosis of acute myocardial infarction or myocardial injury.
S. Wens, G. Schaaf, M. Michels, M. Kruijshaar, T. J. van Gestel, Stijn L. M. in ’t Groen, J. Pijnenburg, D. Dekkers, Jeroen A. A. Demmers, L. Verdijk, E. Brusse, R. V. van Schaik, A. T. van der Ploeg, Pieter A. Van Doorn, W. Pijnappel   +14 more
semanticscholar   +1 more source

Cardioprotective effect of propranolol from alcohol-induced heart muscle damage as assessed by plasma cardiac troponin-T.

, 2001
Background: Heavy alcohol consumption from either long-term misuse or binge drinking is associated with poor cardiac contractility, mitochondrial dysfunction, and ventricular arrhythmias.
Patel, V., Sullivan, A., Richardson, P., Preedy, V.R., Sherwood, R., Ajmal, R.   +5 more
core   +1 more source

Multi‐Omics Insights Into the Mechanisms of Early Muscle Fiber Difference and Transformation Between Lean‐Type and Chinese Indigenous Pigs

Advanced Science, EarlyView.
Multi‐omics analyses uncover breed‐specific cis‐regulatory landscapes and higher‐order chromatin architectural differences that underlie early postnatal muscle fiber divergence in pigs. A super‐enhancer upstream of PPP3CB recruits MEF2C to activate PPP3CB transcription, while the PPP3CB–MEF2C positive feedback loop promotes oxidative muscle fiber ...
Shuailong Zheng, Hainan Wu, Min Liu, Kunpeng Wu, Shuntao Huang, Zulfiqar Ahmed, Lenox Pius, Mengjin Zhu, Dequan Xu   +8 more
wiley   +1 more source

Effect of prolonged exercise in a hypoxic environment on cardiac function and cardiac troponin T

, 2004
Background: Exercise induced cardiac fatigue has recently been observed after prolonged exercise. A moderate to high altitude has been suggested as a possible stimulus in the genesis of such cardiac fatigue. Objective: To investigate if exercise induced
Dawson, E., Whyte, G, Shave, RE, Collinson, P.O., Gaze, D.C., Whyte, G., Dawson, E, George, K., Collinson, P, Gaze, D, Shave, R., George, K   +11 more
core   +1 more source

CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction

Advanced Science, EarlyView.
CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma, Jiali Jia, Juncong Lan, Jing Wang, Dan Rao, Lanlan Rao, Weibin Zhang, Dongpeng Wu, Jie Zhang, Gang Wang, Baohua Liu, Ying Ao, Zimei Wang   +12 more
wiley   +1 more source

Cardiac Biomarkers and Left Ventricular Hypertrophy in Relation to Outcomes in Patients With Atrial Fibrillation: Experiences From the RE‐LY Trial

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Cardiac biomarkers and left ventricular hypertrophy (LVH) are related to the risk of stroke and death in patients with atrial fibrillation.
Ziad Hijazi, Paolo Verdecchia, Jonas Oldgren, Ulrika Andersson, Gianpaolo Reboldi, Giuseppe Di Pasquale, Giovanni Mazzotta, Fabio Angeli, John W. Eikelboom, Michael D. Ezekowitz, Stuart J. Connolly, Salim Yusuf, Lars Wallentin   +12 more
doaj   +1 more source

Leonurine Ameliorates Doxorubicin‐Induced Cardiotoxicity via STING/NF‐κB/NLRP3 Inflammasome Signaling Pathway

Advanced Science, EarlyView.
ABSTRACT Doxorubicin‐induced cardiomyopathy (DIC) remains a dose‐limiting clinical challenge. This study reveals that cardiac vascular endothelial cells (CVECs) act as initial sensors of doxorubicin cardiotoxicity: circulating doxorubicin activates the cGAS‑STING pathway in CVECs, triggering NLRP3 inflammasome‑mediated pyroptosis and release of ...
Wang Jun, Chen Xiaoyang, Xu Jianglin, Yang Zhi, Tao Meijiao, He Jiale, Zhao Jiangfeng, Hei Xuanding, Xu Xuegong, Wang Wei, Li Chun   +10 more
wiley   +1 more source

Associations of elevated cardiac biomarkers with hyperuricemia and mortality in US adults without prevalent cardiovascular disease

Frontiers in Endocrinology
BackgroundNT-proBNP (N-terminal pro-B-type natriuretic peptide), high-sensitivity cardiac troponin T (hs-troponin T), and high-sensitivity cardiac troponin I (hs-troponin I) have been widely recognized as significant cardiac biomarkers, and are ...
Haitao Xie, Le Shen, Le Shen, Peng Yu, Peng Yu, Shi Wang, Shi Wang, Tong Sun, Xueqian Liu, Mengxi Wang, Li Qian, Jiayi Hua, Nan Chen, Xiaohu Chen, Xiaohu Chen, Shuhua Tang, Shuhua Tang   +16 more
doaj   +1 more source

Increased Cardiac Troponin-T in Patients without Myocardial Infarction

Общая реаниматология, 2008
There have been recently reports on elevated levels of cardiac troponins in patients without acute myocardial infarction (AMI). The purpose of the study was to analyze final diagnoses in patients with elevated cardiac troponin-T levels without clinical ...
M. Ya. Krasnoselsky, Ye. V. Koshkina, N. M, Fedorovsky, Ye. V. Goryacheva, A. A. Polupan, A. A. Arefyev, M. Z. Bratanova   +6 more
doaj   +1 more source

Some properties of cardiac troponin T structure [PDF]

Biochemical Journal, 1983
Troponin T is eluted in multiple peaks when the whole bovine cardiac troponin complex is subjected to DEAE-cellulose chromatography in the presence of 8 M-urea. The heterogeneity observed is due to the presence of two forms of troponin T, differing in their Mr values, amino acid content, degree of phosphorylation and aggregation.
N B, Gusev, N V, Barskaya, A D, Verin, I V, Duzhenkova, Z A, Khuchua, A O, Zheltova   +5 more
openaire   +2 more sources