Results 81 to 90 of about 273,643 (353)

Illuminating the Intracellular World: Breakthroughs in Nanoscale Optoelectronics

Advanced Electronic Materials, EarlyView.
This perspective explores optoelectronic biointerfaces spanning macroscale flexible devices to nanoscale intracellular systems, emphasizing their integration across dimensions. It examines capacitive, Faradaic, and photothermal mechanisms that enable light‐driven control of cellular activity and highlights key material and design challenges in ...
Tania Assaf, Menahem Y. Rotenberg
wiley   +1 more source

Phosphorylation Specificities of Protein Kinase C Isozymes for Bovine Cardiac Troponin I and Troponin T and Sites within These Proteins and Regulation of Myofilament Properties*

Journal of Biological Chemistry, 1996
Protein kinase C (PKC) isozymes α, δ, ε, and ζ, shown to be expressed in adult rat cardiomyocytes, displayed distinct substrate specificities in phosphorylating troponin I and troponin T subunits in the bovine cardiac troponin complex. Thus, because they
N. Jideama, T. Noland, R. Raynor, G. Blobe, D. Fabbro, M. Kazanietz, P. Blumberg, Y. Hannun, J. Kuo   +8 more
semanticscholar   +1 more source

Risk stratification of chest pain patients by point-of-care cardiac troponin T and myoglobin measured in the emergency department

, 2006
A prospective multicenter study including 1410 chest pain patients with suspected acute coronary syndromes was carried out to examine the predictive value of biological cardiac markers for adverse events measured by a point-of-care system.
Hirschl, M.M., Ordóñez-Llanos, J., Santaló-Bel, M., Collinson, P.O., Katus, H.A., Gaze, D.C., Haass, M., Zerback, R., Kellett, J., Schulz, I., Derhaschnig, U., Sylvén, C., Chwallek, F., Mueller-Bardorff, M., Mercé-Muntañola J.   +14 more
core   +1 more source

Targeted Anti‐IL‐1 Immunomodulatory Therapy in Pediatric Onset PPP1R13L‐Related Arrhythmogenic Cardiomyopathy

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal recessive loss‐of‐function variants in PPP1R13L cause an ultra‐rare cardiocutaneous syndrome characterized by rapidly progressive arrhythmogenic cardiomyopathy (ACM). PPP1R13L encodes iASPP, which has two potentially overlapping mechanisms driving ACM as both a regulator of NFκB‐mediated inflammation and a binding partner within the ...
Aaron Renberg, Savannah Coppersmith, Owen Merritt, Amer Heider, Adam Helms, Thomas Michniacki, Jack Luxford, Sarah Josephi‐Taylor, Philip Roberts, Joshua Meisner   +9 more
wiley   +1 more source

Multiple Species Comparison of Cardiac Troponin T and Dystrophin: Unravelling the DNA behind Dilated Cardiomyopathy

Journal of Cardiovascular Development and Disease, 2017
Animals have frequently been used as models for human disorders and mutations. Following advances in genetic testing and treatment options, and the decreasing cost of these technologies in the clinic, mutations in both companion and commercial animals ...
Jennifer England, Siobhan Loughna, Catrin Sian Rutland   +2 more
doaj   +1 more source

Perioperative myocardial injury is associated with increased postoperative non-cardiac complications in patients undergoing vascular surgery: a post hoc analysis of a randomised clinical pilot trial

Perioperative Medicine, 2023
Background Elevated cardiac biomarkers, such as high-sensitivity cardiac Troponin T and N-terminal pro-B-type natriuretic peptide improve the prediction of major adverse cardiac events.
A. Valadkhani, A. Gupta, M. Bell
doaj   +1 more source

Prospective validation of a 1-hour algorithm to rule-out and rule-in acute myocardial infarction using a high-sensitivity cardiac troponin T assay

Canadian Medical Association Journal, 2015
Background: We aimed to prospectively validate a novel 1-hour algorithm using high-sensitivity cardiac troponin T measurement for early rule-out and rule-in of acute myocardial infarction (MI).
T. Reichlin, R. Twerenbold, K. Wildi, M. Gimenez, Nathalie Bergsma, P. Haaf, Sophie Druey, C. Puelacher, B. Moehring, M. Freese, C. Stelzig, Lian Krivoshei, P. Hillinger, C. Jäger, Thomas Herrmann, Philipp Kreutzinger, M. Radosavac, Z. M. Weidmann, K. Pershyna, Ursina Honegger, M. Wagener, Thierry Vuillomenet, I. Campodarve, R. Bingisser, Ò. Miró, K. Rentsch, S. Bassetti, S. Osswald, C. Mueller   +28 more
semanticscholar   +1 more source

Q50, an Iron-Chelating and Zinc-Complexing Agent, Improves Cardiac Function in Rat Models of Ischemia/Reperfusion-Induced Myocardial Injury [PDF]

, 2013
Background: Reperfusion of ischemic myocardium may contribute to substantial cardiac tissue damage, but the addition of iron chelators, zinc or zinc complexes has been shown to prevent heart from reperfusion injury.
Faragó, Nóra, Hirschberg Kristóf, Korkmaz S, Merkely Béla Péter, Radovits, Tamás, Hirschberg, Kristóf, Barnucz E, Karck Matthias, Szabó Gábor, Fábián Gabriella, Gyuris Márió, Puskás László G., Loganathan Sivakkanan, Radovits Tamás, Weymann Alexander, Szabó, Csaba, Fábián, Gabriella, Loganathan, Sivakkanan, Karck, Matthias, Merkely, Béla, Kanizsai Iván, Faragó Nóra, Hegedűs Péter, Korkmaz, Sevil, Li Shiliang, Hegedűs, Péter, Gyuris, Márió, Szabó Csaba, Zubarevich Alina, Li, Shiliang, Puskás, László G., Korkmaz Sevil, Ózsvári, Béla, Zubarevich, Alina, Weymann, Alexander, Li S, Merkely Béla, Barnucz, Enikő, Puskás László, Kanizsai, Iván, Szabó, Gábor, Barnucz Enikő, Loganathan S, Ózsvári Béla   +43 more
core   +1 more source

Machine Learning Models of Phase Contrast Images Predict Efficiency of Human Pluripotent Stem Cell Differentiation to Cardiomyocytes

Biotechnology and Bioengineering, EarlyView.
Human pluripotent stem cells were differentiated to cTnT+ cardiomyocytes and imaged throughout the process using phase contrast. We predicted differentiation efficiency (cTnT+ area) from phase contrast and compared model performance with a live‐cell cTnT‐GFP reporter.
Austin K. Feeney, Yaniv Ovadia, Aaron D. Simmons, Christian Elabd, Claire J. Peplinski, Frank Li, Sean P. Palecek   +6 more
wiley   +1 more source

Relationship between serum cardiac troponin T and I with Left ventricular hypertrophy and systolic dysfunction in hemodialysis patients

مجله دانشگاه علوم پزشکی گرگان, 2014
Background and Objective: Cardiovascular diseases are the most frequent cause of death among hemodialysis patients. Left ventricular hypertrophy and systolic dysfunction are potent predictors of cardiovascular morbidity and mortality in hemodialysis ...
Sedighi O, Golshani S, Nikzad F
doaj