Results 151 to 160 of about 8,432 (204)

MKP‐2 Genetic Depletion Modulates Adipose Lipid Composition, Cellular Senescence, and Aging in Mice

Aging Cell, Volume 25, Issue 11, November 2026.
Excess white adipose tissue (WAT) accumulation promotes aging by increasing the risk of insulin resistance and chronic diseases and reduced lifespan. MKP‐2 deficiency protects against premature senescence in cells and WAT and is associated with adipose lipid remodeling, improved metabolic health, and longer lifespan.
Morgan Welch, Nabin Ghimire, Shauri Smith, Cassandra Secunda, Alexis Fink, Alissar Sleiman, Laura Chambliss, Christopher Pinckard, Chloe Reyes, Priya Katta, Anna Ai, Benjamin R. Harrison, Ahmed Lawan   +12 more
wiley   +1 more source

Broad‐Spectrum, Cell Envelope‐Active Marinocyclin Antibiotics From a Coral‐Derived Bacterium Are Effective Against Colistin‐Resistant Bacteria

Angewandte Chemie, Volume 138, Issue 43, 19 October 2026.
Marinocyclins, polycationic macrocyclic depsipeptides, were discovered by genome mining from the marine coral‐derived bacterium Aquimarina megaterium. The compounds have broad‐spectrum activity against gram‐positive and gram‐negative ESKAPE bacteria.
Clara Chepkirui, Sandra Silva, Jan Straetener, Chandrashekhar Padhi, Tina Keller‐Costa, Tess Lamer, Laura Reinke, Heike Brötz‐Oesterhelt, Rodrigo Costa, Jörn Piel   +9 more
wiley   +2 more sources

ALCAT1-mediated abnormal cardiolipin remodelling promotes mitochondrial injury in podocytes in diabetic kidney disease

Cell Communication and Signaling
Background Cardiolipin (CL) plays a critical role in maintaining mitochondrial membrane integrity and overall mitochondrial homeostasis. Recent studies have suggested that mitochondrial damage resulting from abnormal cardiolipin remodelling is associated
Yiqun Hao, Yanqin Fan, Jun Feng, Zijing Zhu, Zilv Luo, Hongtu Hu, Weiwei Li, Hongxia Yang, Guohua Ding   +8 more
doaj   +1 more source

Cardiolipin [PDF]

Science-Business eXchange, 2012
openaire   +1 more source

A pro‐inflammatory cytokine signature characterises thrombotic antiphospholipid syndrome despite stable anticoagulation

British Journal of Haematology, Volume 209, Issue 5, Page 2233-2243, November 2026.
Primary antiphospholipid syndrome comprises distinct inflammatory subgroups defined by cytokine profiling. A shared pro‐inflammatory signature is present across all patients, whereas arterial thrombosis demonstrates enhanced inflammatory activation compared with venous thrombosis, suggesting divergent pathogenic mechanisms and opportunities for ...
Catherine B. Ducker, Megan V. Preece, Jeremy Schofield, Charis Pericleous, Mike Laffan, Simon Abrams, Deepa J. Arachchillage   +6 more
wiley   +1 more source

Aptamer‐mediated outer membrane destabilization overcomes low permeability resistance in Pseudomonas aeruginosa

The FEBS Journal, Volume 293, Issue 21, Page 6349-6373, November 2026.
DNA aptamers, Apt 60 and Apt 173, target the BamA protein to compromise outer membrane integrity in Pseudomonas aeruginosa, making it susceptible to Azithromycin, an antibiotic that is otherwise poorly effective due to the low‐permeability membrane.
Rupany Selvam, Michelle Khai Khun Yap, Rafael Giacomazzi, Sérgio F. Sousa, Hock Siew Tan   +4 more
wiley   +1 more source

Hypercapnia Induces Mitochondrial Adaptations and Alters Glutamine Metabolism to Drive a Distinct Metabolic Phenotype in Monocytes

Immunology &Cell Biology, Volume 104, Issue 10, Page 943-963, November‐December 2026.
Elevated CO2 (hypercapnia) is a feature of serious lung diseases, for example COPD and contributes to poor patient prognosis through modulation of immune cell function. Here we employ state‐of‐the art metabolomic and isotope tracing approaches to reveal CO2‐dependent mitochondrial alterations linked to suppressed ATP, proline and glutamate levels in ...
Ben Reddan, David E. Phelan, Xiaofei Yin, Lorraine Brennan, Martina Wallace, Eoin P. Cummins   +5 more
wiley   +1 more source

Cargo Stability of Extracellular Vesicles Derived From Non‐Diseased Sources: Effects of Storage and Handling Conditions

Journal of Cellular and Molecular Medicine, Volume 30, Issue 21, November 2026.
ABSTRACT Extracellular vesicles (EVs) are nanoscale, membrane‐enclosed particles that transfer proteins, nucleic acids, lipids, and other bioactive molecules between cells. Their cargo‐bearing capacity supports applications in drug delivery, regenerative medicine, and biomarker development, but ex vivo handling can alter vesicle recovery and cargo ...
Khadijeh Abbasi, Mina Mohammadinasr, Roza Motavalli, Narges Arianfar, Attabak Toofani‐Milani, Moein Shirzad, Vahid Hosseini, Masoud Darabi   +7 more
wiley   +1 more source

Chemistry of Cardiolipin

YAKUGAKU ZASSHI, 1964
openaire   +3 more sources

Mapping syphilis surveillance: Insights into blood donation screening practices worldwide

Vox Sanguinis, Volume 121, Issue 11, Page 1674-1684, November 2026.
Abstract Background and Objectives Syphilis is caused by the bacterial spirochete Treponema pallidum and can be transmitted through blood transfusion. However, there have been less than 10 documented transfusion‐transmitted cases since World War II.
Michel‐Andrés García‐Otálora, Guillermo Orjuela‐Falla, Carl P. McDonald, Sandra Ramirez‐Arcos, ISBT Transfusion‐Transmitted Infectious Diseases Working Party Subgroup on Bacteria   +4 more
wiley   +1 more source