Results 141 to 150 of about 39,995 (259)

Reorganization of Innate Immune Cell Lipid Profiles by Bioinspired Meroterpenoids to Limit Inflammation

Advanced Science, Volume 13, Issue 59, 23 October 2026.
Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Lorenz Waltl, David Holubek, Klaus Speck, Raphael Wildermuth, Franz‐Lucas Haut, Stephan Permann, Immanuel Plangger, Christian Steinborn, Zhigang Rao, Danilo D'Avino, Ida Cerqua, Julia Stadler, Fiorentina Roviezzo, Peter Schlenke, Anita Siller, Harald Schennach, Solveigh C. Koeberle, Eva‐Maria Pferschy‐Wenzig, Antonietta Rossi, Thomas Magauer, Andreas Koeberle   +20 more
wiley   +1 more source

Mitochondria‐Targeted Nanotherapeutics: A Promising Strategy in Modulating Mitochondrial Function, Transfer, and Transplantation

Advanced Science, Volume 13, Issue 58, 19 October 2026.
This review summarizes the pathogenic role of mitochondria in diseases and highlights mitochondrial transfer and transplantation as emerging therapeutic strategies. It systematically discusses how nanomaterials are engineered to facilitate these processes, and critically examines the current challenges and future perspectives for their clinical ...
Yuanyuan Su, Zhiyan Gong, Jiao Mu, Lili Huang, Pengfei Yang, Chenli Zhang, Lingshan Zhao, Liling Yang, Jun Deng, Xiaohui Liao   +9 more
wiley   +1 more source

ALCAT1-mediated abnormal cardiolipin remodelling promotes mitochondrial injury in podocytes in diabetic kidney disease

Cell Communication and Signaling
Background Cardiolipin (CL) plays a critical role in maintaining mitochondrial membrane integrity and overall mitochondrial homeostasis. Recent studies have suggested that mitochondrial damage resulting from abnormal cardiolipin remodelling is associated
Yiqun Hao, Yanqin Fan, Jun Feng, Zijing Zhu, Zilv Luo, Hongtu Hu, Weiwei Li, Hongxia Yang, Guohua Ding   +8 more
doaj   +1 more source

Ciliary Membrane Lipid Homeostasis in Health and Disease

Advanced Science, Volume 13, Issue 58, 19 October 2026.
This review systematically delineates the distinct lipid landscapes of ciliary membranes, including the spatial organization of phosphoinositides, cholesterol, and sphingolipids. It elucidates how these lipids orchestrate ciliogenesis, signal transduction, and membrane dynamics in cilia beating, and highlights how their dysregulation drives ...
Zhenzhou Huang, Yuan‐yuan Liu, Hanqi Sun, Peiwei Liu   +3 more
wiley   +1 more source

Cardiolipin [PDF]

Science-Business eXchange, 2012
openaire   +1 more source

Molecular Machine‐Driven Fluorogenic Probes for Motion–Signal Conversion and Hydrophilicity Retention in Live‐Cell Nanoscopy

Aggregate, Volume 7, Issue 10, October 2026.
A hydrophilicity‐retention strategy for developing fluorogenic probes by conjugating malachite green (as the molecular motion switch) with a spirocyclization‐free rhodamine (as the signal module) was developed for nanoscopic imaging of mitochondrial cristae structures and dynamics in living cells.
Yuan Luo, Lili Du, Xing Yang, Ke Liu, Chunbai Xiang, Yuanyuan Wang, Daoyong Jiang, Zihan Wu, Xiang‐Yang Lou, Xiaokang Zhang, Jiajie Diao, Xiaoshuai Huang, Ping Gong, Ben Zhong Tang, Lintao Cai, Pengfei Zhang   +15 more
wiley   +1 more source

CDS2 Drives Tumor Progression in Epithelial Ovarian Cancer via the PI3K/AKT Pathway

Cancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Background Epithelial ovarian cancer (EOC) frequently disseminates within the lipid‐rich peritoneal cavity, where tumor progression is accompanied by metabolic adaptations involving lipid utilization and mitochondrial function. Although these metabolic alterations are increasingly recognized as important features of EOC progression and ...
Lixue Cao, Yanzhen Chen, Yingqi Liu, Changnian Yang, Zhentao Zhang, Yongqing Lin, Yiyuan Wang, Siman Chen, Fei Yu, Haiyan Ye, Shanshan Wu   +10 more
wiley   +1 more source

THE COMPOSITION OF CARDIOLIPIN

Journal of Biological Chemistry, 1947
openaire   +2 more sources

Chemistry of Cardiolipin

YAKUGAKU ZASSHI, 1964
openaire   +3 more sources

Stem Cell and EV/sEV Strategies for Neuroimmune Niche Reprogramming in Selected CNS Disorders: Mechanisms, Engineered Delivery, and Translational Readiness

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
Stem cell‐ and EV/sEV‐based interventions may reprogram the CNS neuroimmune niche by suppressing glial inflammation, enhancing trophic and synaptic support, stabilizing BBB communication, and improving metabolic resilience. Clinical translation will require mechanism‐linked potency assays, MISEV‐aligned EV reporting, biodistribution, GMP manufacturing,
Wenjing Lu, Junqiang Yan, Hongfang Feng
wiley   +1 more source