After delivery: How recipient cells shape the fate and function of transplanted mitochondria
Recipient‐cell handling shapes how transplanted mitochondria contribute after delivery, linking donor competence, recipient state and exposure duration to intracellular fate. The framework matches transient rescue, sustained functional support and durable mitochondrial DNA correction to the evidence and product attributes required for each therapeutic ...
Zhi‐Yuan Zhang +3 more
wiley +1 more source
Making sense of cardiomyopathy caused by deletion of acetyl-CoA carboxylase 1 and 2. Reply. [PDF]
Kim CW, Mitsche MA, Horton JD.
europepmc +1 more source
Abstract Lipids are central to animal physiology, underpinning energy storage, membrane architecture, and cell signaling. Targeted lipid studies in wild animals have already demonstrated that lipid adjustments, such as shifts in energy storage and membrane composition, are key molecular responses to environmental stressors.
André L. R. Cuenca +5 more
wiley +1 more source
Making sense of cardiomyopathy caused by deletion of acetyl-CoA carboxylase 1 and 2. [PDF]
Tian R, Lewandowski ED.
europepmc +1 more source
Aging of Skeletal Muscle: From Molecular Mechanisms to Therapeutic Interventions
Skeletal muscle aging is driven by coordinated local breakdown across myofibers, stem and stromal cells, immune and vascular compartments, and neuromuscular control. These mechanisms promote mitochondrial dysfunction, inflammation, senescence, impaired regeneration, fibrosis, myosteatosis, denervation, and functional decline.
Ting Liu, Yaomin Hu
wiley +1 more source
Endothelin-1 and Anticardiolipin Antibodies in Primary Biliary Cholangitis Patients with Portal Hypertension: A Pilot Retrospective Study. [PDF]
Bauer A, Rawa T, Bauer T.
europepmc +1 more source
Iron and Other Metal Ions in Human Health and Disease
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley +1 more source
Mitochondrial immunometabolism in sepsis: bridging immune cell dysfunction and organ failure. [PDF]
Zhang X +5 more
europepmc +1 more source
Alveolar macrophages: development, respiratory homeostasis, signal pathways, diseases, and therapeutic opportunities: During embryonic development, fetal progenitors migrate to the developing lungs via a CX3CR1‐dependent mechanism to establish the TrAM pool.
Sihan Yang +4 more
wiley +1 more source
The physicochemical design, structure and permeability of the JCVI-syn3A minimal cell membrane. [PDF]
Presutti C +8 more
europepmc +1 more source

