Results 81 to 90 of about 36,776 (242)

Evaluation of the Application of Urea Dissociation Treatment to Reduce the False‐Positive Rate of ELISA for Syphilis Detection

Journal of Clinical Laboratory Analysis, EarlyView.
Exploring the application of urea dissociation treatment to reduce the false‐positive rate of ELISA for syphilis detection. From January 2023 to January 2024, seven false‐positive syphilis samples were collected from Xi'an Regional Medical Laboratory Centre as the experimental group, five positive specimens as the control group, and five negative ...
Jiao Wang, Bin Li, Haodi Li, Xucai Dong
wiley   +1 more source

Linoleic acid supplemention of Barth syndrome fibroblasts restores cardiolipin levels: implications for treatment

Journal of Lipid Research, 2003
The object of this study was to investigate whether the levels of cardiolipin in cultured skin fibroblasts of patients with Barth syndrome (BTHS) can be restored by addition of linoleic acid to growth media.
F. Valianpour, R.J.A. Wanders, H. Overmars, F.M. Vaz, P.G. Barth, A.H. van Gennip   +5 more
doaj   +1 more source

Preliminary Evaluation of a Novel Lupus Anticoagulant Activity Assay Unaffected by Anticoagulants

Journal of Clinical Laboratory Analysis, EarlyView.
A novel one‐step lupus anticoagulant (LA) assay based on the LA‐sensitivity ratio (LA‐SR) was developed to simplify diagnostic testing and reduce potential interference from anticoagulants. The LA‐SR method showed good agreement with guideline‐based LA testing (dRVVT and/or LA‐sensitive APTT) for the detection of LA and demonstrated limited influence ...
Ayu Hidaka, Risa Kaneshige, Seika Nakamura, Yukari Motoki, Junzo Nojima   +4 more
wiley   +1 more source

Figure 5: Tetralinoleoyl Cardiolipin With Elamipretide Treatment [PDF]

, 2019
(A) The effect of HF on tetralinoleoyl cardiolipin (mass-to-charge ratio, 1,448) in untreated samples is expressed as a percentage of total cardiolipin.
Genevieve C. Sparagna (299454), Brian L. Stauffer (6820697), Kathryn C. Chatfield (646110), Shelley D. Miyamoto (6820694), Max B. Mitchell (6820688), Carmen C. Sucharov (6820691), Elisabeth K. Phillips (6820685), Muhammad Aftab (4261855), Sarah Chau (6820682), Amrut V. Ambardekar (396783)   +9 more
core   +1 more source

SIRT3 and SIRT5 regulate the enzyme activity and cardiolipin binding of very long-chain acyl-CoA dehydrogenase. [PDF]

PLoS ONE, 2015
SIRT3 and SIRT5 have been shown to regulate mitochondrial fatty acid oxidation but the molecular mechanisms behind the regulation are lacking. Here, we demonstrate that SIRT3 and SIRT5 both target human very long-chain acyl-CoA dehydrogenase (VLCAD), a ...
Yuxun Zhang, Sivakama S Bharathi, Matthew J Rardin, Radha Uppala, Eric Verdin, Bradford W Gibson, Eric S Goetzman   +6 more
doaj   +1 more source

A Refractory Leg Skin Ulcer Associated With Multiple Myeloma Successfully Treated With Plasma Exchange, Lenalidomide, and Dexamethasone

JEADV Clinical Practice, EarlyView.
ABSTRACT Multiple myeloma (MM) is a malignant plasma cell disorder that primarily presents with CRAB symptoms (calcium elevation, renal failure, anemia, and bone abnormalities). In rare cases, MM manifests with systemic complications like skin ulcers, which present management challenges. Here, we report a 78‐year‐old Japanese man with MM and refractory
Naoko Hattori, Yutaka Kuwatsuka, Tomoka Waseda, Daisuke Ehara, Koji Ando, Hiroyuki Murota   +5 more
wiley   +1 more source

Structure of an Inner Membrane Protein Required for PhoPQ-Regulated Increases in Outer Membrane Cardiolipin

mBio, 2020
The Salmonella enterica subsp. enterica serovar Typhimurium PhoPQ two-component system is activated within the intracellular phagosome environment, where it promotes remodeling of the outer membrane and resistance to innate immune antimicrobial peptides.
Junping Fan, Erik M. Petersen, Thomas R. Hinds, Ning Zheng, Samuel I. Miller   +4 more
doaj   +1 more source

The physicochemical properties of cardiolipin bilayers and cardiolipin-containing lipid membranes

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2009
In this review article, we summarize the current state of biophysical knowledge concerning the phase behavior and organization of cardiolipin (CL) and CL-containing phospholipid bilayer model membranes. We first briefly consider the occurrence and distribution of CL in biological membranes and its probable biological functions therein. We next consider
Lewis, Ruthven N.A.H., McElhaney, Ronald N.   +1 more
openaire   +2 more sources

Lipid Coating Modulates Effects of Nanoceria on Oxidative Metabolism in Human Embryonic Lung Fibroblasts: A Case of Cardiolipin

Biomolecules
The unique redox properties of nanoscale cerium dioxide determine its diverse application in biology and medicine as a regulator of oxidative metabolism. Lipid modifiers of the nanoparticle surface change their biochemical properties and bioavailability.
Elena V. Proskurnina, Madina M. Sozarukova, Elizaveta S. Ershova, Ekaterina A. Savinova, Larisa V. Kameneva, Natalia N. Veiko, Maria A. Teplonogova, Vladimir P. Saprykin, Vladimir K. Ivanov, Svetlana V. Kostyuk   +9 more
doaj   +1 more source

Loss of cardiac tetralinoleoyl cardiolipin in human and experimental heart failure

Journal of Lipid Research, 2007
The mitochondrial phospholipid cardiolipin is required for optimal mitochondrial respiration. In this study, cardiolipin molecular species and cytochrome oxidase (COx) activity were studied in interfibrillar (IF) and subsarcolemmal (SSL) cardiac ...
Genevieve C. Sparagna, Adam J. Chicco, Robert C. Murphy, Michael R. Bristow, Christopher A. Johnson, Meredith L. Rees, Melissa L. Maxey, Sylvia A. McCune, Russell L. Moore   +8 more
doaj   +1 more source