Results 101 to 110 of about 39,995 (259)

Survival among patients with systemic sclerosis‐associated pulmonary arterial hypertension in the Australian scleroderma cohort study

Internal Medicine Journal, EarlyView.
Abstract Background and Aims Systemic sclerosis (scleroderma; SSc) patients can develop pulmonary arterial hypertension (PAH), which is a leading cause of death. We sought to evaluate severity, therapeutic strategy and survival of SSc‐PAH in the Australian Scleroderma Cohort Study (ASCS).
Zoe Brown, Dylan Hansen, Kathleen Morrisroe, Nava Ferdowsi, Laura Ross, Wendy Stevens, Maryam Tabesh, Joanne Sahhar, Gene‐Siew Ngian, Diane Apostolopoulos, Kimti Kumar, Jennifer G. Walker, Susanna Proudman, Mandana Nikpour   +13 more
wiley   +1 more source

Effect of Cardiolipin Oxidation on Solid-Phase Immunoassay for Antiphospholipid Antibodies

, 2001
SummaryDiagnostic assays for antiphospholipid antibodies are routinely performed on microtitre plates coated with cardiolipin. Here we show that contact between cardiolipin and NUNC-Immuno® plates leads to extensive oxidation, generating a series of ...
Ivan Haller, Michael Schlame, Lisa Sammaritano, Thomas Blanck   +3 more
core   +1 more source

Placental malperfusion and angiogenesis‐related proteins are associated with small‐for‐gestational‐age in systemic lupus erythematosus

Journal of Internal Medicine, EarlyView.
Abstract Background Although systemic lupus erythematosus (SLE) pregnancy frequently results in small for gestational age (SGA) infants, the understanding of underlying mechanisms is limited. We aimed to identify specific histological patterns of placental injury in SGA in SLE and to explore whether an altered balance of angiogenesis‐related proteins ...
Marit Stockfelt, Henri Puttonen, Ing‐Marie Fyhr, Agnes Torell, Kerstin Andersson, Iva Gunnarsson, Elisabet Svenungsson, Agneta Zickert, Maria Majczuk Sennström, Estelle Trysberg, Anders A. Bengtsson, Andreas Jönsen, Helena Strevens, Christopher Sjöwall, Muna Saleh, Sofia Pihl, Dag Leonard, Lars Rönnblom, Tansim Akhter, Bo Jacobsson, Anna‐Carin Lundell, Anna Rudin   +21 more
wiley   +1 more source

Anti-cardiolipin antibodies and HIV infection

, 1990
SUMMARY Anti-cardiolipin antibodies of IgG class were found in 48% of intravenous drug users, 38% of homosexuals and 14% of heterosexuals (with no other risk factor) infected with HIV.
C MACLEAN, P J FLEGG, D C KILPATRICK
core   +1 more source

Embryonal degreening and seed longevity require plastid LEA proteins

New Phytologist, EarlyView.
Working model of how plastidial LEA proteins aid the remodelling of photosynthetic structures during degreening of Arabidopsis seed embryos. LEA42 and LEA48 support thylakoid proteostasis and membrane remodelling in embryonal cells during late seed maturation by maintaining a local physicochemical environment compatible with protein turnover and ...
Dennis Brandt, Ana Carolina Vilchez, Jürgen Eirich, Paulina Heinkow, Lea Hembach, Ke Zheng, Pedro Barreto, Jan‐Ole Niemeier, Lando Lebok, Ivo Feussner, Felix Buchert, Alexey Amunts, Kristina Kühn, David Macherel, Till Ischebeck, Michael Melzer, Iris Finkemeier, Markus Schwarzländer   +17 more
wiley   +1 more source

Role of disorders related to idiotypic and anti-idiotypic interactions in slowing down the achievement of negative serologic reactions in patients with early onset forms of syphilis after specific therapy

Vestnik Dermatologii i Venerologii, 2017
Goal. To study the humoral immunity state in patients with the slowed down achievement of negative serologic reactions after the treatment of early onset forms of syphilis by means of examining the blood serum level of idiotypic and anti-idiotypic ...
YE. N. Volkova, S. G. Morozov, YE. V. Mitichkina, A. A. Grigoriyeva, I. V. Yelistratova   +4 more
doaj   +1 more source

Revisiting the action spectrum of DNA damage: Chemiexcitation and the expanded biological spectrum of cyclobutane pyrimidine dimer formation

Photochemistry and Photobiology, EarlyView.
UVB and UVA generate cyclobutane pyrimidine dimers (CPDs) during irradiation (purple). After exposure ends, chemiexcitation in pigmented melanocytes continues to generate delayed CPDs (yellow), even as repair removes some pre‐existing lesions. Consequently, total CPD burden can rise while visible erythema fades.
Jyoti Srivastava, Marcus S. Cooke, Sanjay Premi   +2 more
wiley   +1 more source

Synthetic Approaches to Cardiolipin Analogs [PDF]

, 2020
The first portion of this document describes the synthesis of three examples of the mitochondrial phospholipid cardiolipin with different fatty acid chain lengths and degrees of unsaturation.
Frasso, Michael
core  

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Mitochondrial Metabolic Reprogramming in Glioma: Mechanisms of Tumorigenesis and Implications for Clinical Therapy. [PDF]

CNS Neurosci Ther
In gliomas, mitochondria integrate glucose, lipid, protein, and nucleotide metabolism to support proliferation, invasion, treatment resistance, and adaptation, with D‐2‐hydroxyglutarate‐driven remodeling in IDH‐mutant tumors and diverse metabolic states in IDH wild‐type glioblastomas.
Jiang L, Li M, Li Z, Liu Q, Li Y.
europepmc   +2 more sources