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Mammalian cardiolipin biosynthesis
Chemistry and Physics of Lipids, 2014Cardiolipin is a major phospholipid in mitochondria and is involved in the generation of cellular energy in the form of ATP. In mammalian and eukaryotic cells it is synthesized via the cytidine-5'-diphosphate-1,2-diacyl-sn-glycerol phosphate pathway. This brief review will describe some of the more recent studies on mammalian cardiolipin biosynthesis ...
Edgard M Mejia, Grant M Hatch
exaly +3 more sources
Cardiolipin, the heart of mitochondrial metabolism
Cardiolipin is a unique phospholipid, which is almost exclusively localized in the mitochondrial inner membrane where it is synthesized from phosphatidylglycerol and cytidinediphosphate-diacylglycerol.
Riekelt H Houtkooper, F M Vaz
exaly +2 more sources
Identification and characterization of human cardiolipin synthase
The mitochondrial phospholipid cardiolipin is synthesized from cytidinediphosphate-diacylglycerol and phosphatidylglycerol, a process catalyzed by the enzyme cardiolipin synthase.
Riekelt H Houtkooper +2 more
exaly +2 more sources
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2002
Cardiolipin (CL) is recognized to be an essential phospholipid in eukaryotic energy metabolism so that physiological and pathological perturbations in its synthetic and catabolic pathways play key roles in maintaining mitochondrial structure and function, and ultimately cell survival.
Jeanie B, McMillin, William, Dowhan
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Cardiolipin (CL) is recognized to be an essential phospholipid in eukaryotic energy metabolism so that physiological and pathological perturbations in its synthetic and catabolic pathways play key roles in maintaining mitochondrial structure and function, and ultimately cell survival.
Jeanie B, McMillin, William, Dowhan
openaire +2 more sources

