Results 241 to 250 of about 66,906 (291)

Dynamic Cardiolipin Synthesis Is Required for CD8+ T Cell Immunity

Cell Metabolism, 2020
Summary Mitochondria constantly adapt to the metabolic needs of a cell. This mitochondrial plasticity is critical to T cells, which modulate metabolism depending on antigen-driven signals and environment.
Mauro Corrado, David E Sanin, Maaike Jacobs   +2 more
exaly   +2 more sources

Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis

Cell Metabolism, 2018
Summary Activation of energy expenditure in thermogenic fat is a promising strategy to improve metabolic health, yet the dynamic processes that evoke this response are poorly understood.
Tao Ma, Matthew D Lynes, Iuliia Karavaeva   +2 more
exaly   +2 more sources

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Extracellular cardiolipin modulates microglial phagocytosis and cytokine secretion in a toll-like receptor (TLR) 4-dependent manner.

Journal of Neuroimmunology, 2021
Microglia-driven neuroinflammation contributes to neurodegenerative diseases. Mitochondrial phospholipid cardiolipin acts as a signaling molecule when released from damaged cells.
Tyler J. Wenzel, Athena L. Ranger, Seamus A. McRae, A. Klegeris   +3 more
semanticscholar   +1 more source

Photoreactive cardiolipin analogues

Chemistry and Physics of Lipids, 1988
New photoreactive analogues of cardiolipin have been chemically synthesized. Photoreactive aryl azido acyl groups were placed at two different locations within the cardiolipin molecule: at the 2-sn position of the 2-sn glycerol of cardiolipin; at the 2-sn position of the 3-sn-phosphatidyl group; or at both locations to provide a dual labeled analogue ...
W T, Fowler, J D, Lambeth, G L, Powell
openaire   +2 more sources

Cardiolipin and apoptosis

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2002
Cardiolipin (CL) is recognized to be an essential phospholipid in eukaryotic energy metabolism so that physiological and pathological perturbations in its synthetic and catabolic pathways play key roles in maintaining mitochondrial structure and function, and ultimately cell survival.
Jeanie B, McMillin, William, Dowhan
openaire   +2 more sources

Mammalian cardiolipin biosynthesis

Chemistry and Physics of Lipids, 2014
Cardiolipin is a major phospholipid in mitochondria and is involved in the generation of cellular energy in the form of ATP. In mammalian and eukaryotic cells it is synthesized via the cytidine-5'-diphosphate-1,2-diacyl-sn-glycerol phosphate pathway. This brief review will describe some of the more recent studies on mammalian cardiolipin biosynthesis ...
Edgard M, Mejia, Hieu, Nguyen, Grant M, Hatch   +2 more
openaire   +2 more sources

Cardiolipin antibody assays

Lancet, The, 1990
exaly   +2 more sources

Mitochondrial dysfunction in metabolic and cardiovascular diseases associated with cardiolipin remodeling.

Biochimica et Biophysica Acta - Molecular Basis of Disease, 2020
Cardiolipin (CL) is an acidic phospholipid almost exclusively found in the inner mitochondrial membrane, that not only stabilizes the structure and function of individual components of the mitochondrial electron transport chain, but regulates relevant ...
M. El-Hafidi, F. Correa, C. Zazueta
semanticscholar   +1 more source