Results 171 to 180 of about 8,226 (286)
ChemBioChem, Volume 27, Issue 2, January 2026.Purification of full‐length Bcl‐2 proteins comes with challenges resulting in several studies being done on various truncated variants. This article presents a protocol to obtain pure monomeric full‐length Bcl‐xL, which shuttles between the membrane and aqueous environments, and retains the ability to perform the direct and indirect modes of cell death
Christina Elsner +6 more
wiley +1 more source
Engineering Liposomes for Neurodegenerative Diseases: Targeted Delivery and Regenerative Potential
ChemNanoMat, Volume 12, Issue 1, January 2026.Liposomal nanocarriers offer therapeutic promise for neurodegenerative diseases by encapsulating diverse agents such as neurotrophic factors and mRNA while targeting the blood‐brain barrier. Designed to stimulate neuronal repair and restore function, these lipid vesicles advance strategies for optimized design and central nervous system delivery ...
Oybek Ashirov +3 more
wiley +1 more source
HEPES in Cell Culture Alters the Multi‐Omics Profile Exhibited by Gaucher Disease Fibroblasts
Journal of Cellular Biochemistry, Volume 127, Issue 1, January 2026.ABSTRACT Lysosomal function can be affected by components in cell culture. This in turn may influence cellular metabolism and, consequently, research and diagnostics outcomes. One such component is the commonly used pH buffer 4‐(2‐hydroxyethyl)‐1‐piperazineethanesulfonic acid (HEPES).
Eleonore M. Corazolla +14 more
wiley +1 more source
Cardiolipin Effects on the Gating Behaviour and Reconstitution of MscL and MscS [PDF]
, 2011 Andrew R. Battle +2 more
openalex +1 more source
IgMk paraprotein from gammopathy patient can bind to cardiolipin and interfere with coagulation assay: a case report [PDF]
, 2017 Xinyao Wu +4 more
openalex +1 more source
Respirology Case Reports, Volume 14, Issue 1, January 2026.This report presents a case of systemic lupus erythematosus with multiple hospitalizations over 3 years due to unexplained respiratory symptoms (dyspnea, reduced lung volume, elevated diaphragm, coughing, and chest pain), ultimately diagnosed with shrinking lung syndrome (a rare complication of lupus without established treatment) and successfully ...
Somayeh Motamed +5 more
wiley +1 more source
A Global Metabolomic and Lipidomic Landscape of Human Plasma Across the Lifespan
Aging Cell, Volume 25, Issue 1, January 2026.Liu et al. provide a comprehensive analysis of dynamic plasma metabolomic and lipidomic changes in humans across the lifespan, identifying age‐specific metabolic trajectories and developing a metabolite‐based aging clock, offering insights into metabolic reprogramming and potential biomarkers for aging‐related health interventions.
Xinru Liu +6 more
wiley +1 more source
Bioenergetics and lipid metabolism in Alzheimer's disease: From cell biology to systemic health
Journal of Internal Medicine, Volume 299, Issue 1, Page 20-43, January 2026.Abstract Alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by progressive cognitive decline. Although amyloid‐β and tau pathologies remain central to our understanding of AD, growing evidence suggests that disrupted lipid metabolism and impaired bioenergetics are closely linked to these hallmark features. Genetic, lipidomic
Silvia Maioli +12 more
wiley +1 more source
Cardiolipin as an oxidative target in cardiac mitochondria in the aged rat
, 2008 Edward J. Lesnefsky, Charles L. Hoppel
openalex +1 more source