Results 81 to 90 of about 4,979,977 (315)

Noninvasive tests for nonalcoholic fatty liver disease in a multi‐ethnic population: The HELIUS study

Hepatology Communications, EarlyView., 2022
Abstract Nonalcoholic fatty liver disease (NAFLD) is increasing in prevalence and severity globally, prompting noninvasive testing, yet limited data exist on noninvasive liver tests (NITs) including transient elastography (TE) in ethnically diverse populations.
Anne‐Marieke van Dijk, Yasaman Vali, Anne Linde Mak, Henrike Galenkamp, Max Nieuwdorp, Bert‐Jan van den Born, Adriaan Georgius Holleboom   +6 more
wiley   +1 more source

Depression, cardiometabolic disease, and their co-occurrence after childhood maltreatment: an individual participant data meta-analysis including over 200,000 participants

BMC Medicine, 2023
Background Childhood maltreatment is associated with depression and cardiometabolic disease in adulthood. However, the relationships with these two diseases have so far only been evaluated in different samples and with different methodology.
Camille Souama, Femke Lamers, Yuri Milaneschi, Christiaan H. Vinkers, Serena Defina, Linda Garvert, Frederike Stein, Tom Woofenden, Katharina Brosch, Udo Dannlowski, Henrike Galenkamp, Ron de Graaf, Vincent W. V. Jaddoe, Anja Lok, Bas B. van Rijn, Henry Völzke, Charlotte A. M. Cecil, Janine F. Felix, Hans J. Grabe, Tilo Kircher, Karim Lekadir, Margreet ten Have, Esther Walton, Brenda W. J. H. Penninx, on behalf of the EarlyCause consortium   +24 more
doaj   +1 more source

Encapsulated Leptin‐Producing Cells Facilitate Entrainment of Circadian Rhythms in Rodents and Nonhuman Primates

Advanced Science, EarlyView.
A clinically translatable cell line can be engineered to produce leptin, encapsulated in biomaterial and safely implanted to produce and deliver the metabolic regulating protein within the body. Implantation of these encapsulated cells decreases the time it takes for mice and non‐human primates to adjust to circadian disruptions similar to those ...
Samantha T. Fleury, Xuanyi Lin, Peter D. Rios, Christopher Olker, Eun Joo Song, Alejandra Cobos Perez, Cody Fell, Daisy Lopez, Ira Joshi, Hafsa Nasir, Cecelia Curtis, Danna Muringi, Kaiyuan Wang, José Oberholzer, Fred W. Turek, Isaac B. Hilton, Jonathan Rivnay, Martha Hotz Vitaterna, Omid Veiseh   +18 more
wiley   +1 more source

Consumption of ultra-processed foods and risk of multimorbidity of cancer and cardiometabolic diseases: a multinational cohort study [PDF]

, 2023
BACKGROUND: It is currently unknown whether ultra-processed foods (UPFs) consumption is associated with a higher incidence of multimorbidity. We examined the relationship of total and subgroup consumption of UPFs with the risk of multimorbidity defined ...
Schulze, Matthias B, Peruchet-Noray, Laia, Ferrari, Pietro, Viallon, Vivian, Jakszyn, Paula, Guevara, Marcela, Borné, Yan, Freisling, Heinz, Aglago, Elom K, Cordova, Reynalda, Huybrechts, Inge, Tjønneland, Anne, Wagner, Karl-Heinz, Kyrø, Cecilie, Boer, Jolanda M A, Verschuren, W M Monique, Huerta, José María, Ricceri, Fulvio, Tumino, Rosario, van der Schouw, Yvonne T, Aune, Dagfinn, Fontvieille, Emma, Katzke, Verena, Millett, Christopher, Amiano, Pilar, Redondo-Sánchez, Daniel, Sieri, Sabina, Jansana, Anna, Tsilidis, Konstantinos K, Bajracharya, Rashmita, Heath, Alicia K, Masala, Giovanna, Sonestedt, Emily, Panico, Salvatore, Gunter, Marc J   +34 more
core  

Pulse pressure associates with severity and worse outcomes in patients with stable coronary artery disease

npj Cardiovascular Health
The association of pulse pressure (PP) with the severity and cardiovascular (CV) outcomes in stable coronary artery disease populations with normal ejection fraction are sparse.
Yan Zhang, Sha Li, Hui-Wen Zhang, Yuan-Lin Guo, Na-Qiong Wu, Cheng-Gang Zhu, Rui-Xia Xu, Jie Qian, Ke-Fei Dou, Jian-Jun Li   +9 more
doaj   +1 more source

Sex‐ and Time‐Resolved Physiological and Gut Ecosystem Responses to a Food‐Grade Microbiome‐Targeted Intervention in Collegiate Endurance Athletes

Advanced Science, EarlyView.
In collegiate endurance athletes, a 6‐week randomized CPYE intervention yielded time‐ and sex‐dependent shifts in field‐based cardiorespiratory, metabolic, and redox indices, accompanied by changes in gut multi‐omics profiles. An exploratory extension during intensified training generates hypotheses warranting future validation.
Meng Zhang, Le Ge, Kaiyang Liu, Yanrong Liu, Guolin Zhao, Lai‐Yu Kwok, Zheng Sun, Zhihong Sun, Wenyi Zhang   +8 more
wiley   +1 more source

Genetic variation, adipokines, and cardiometabolic disease

, 2020
Adipokines are adipocyte-secreted cell signalling proteins that travel to distant target organs and tissues, where they regulate a variety of biological actions implicated in cardiometabolic health.
Metz, Sophia, Huang, Lam Opal, Kilpeläinen, Tuomas O.   +2 more
core   +1 more source

Improving prevention strategies for cardiometabolic disease [PDF]

, 2020
There is a growing burden of cardiometabolic disease in many parts of the world. Despite some progress in its prevention, more can be done to tackle risks of its development in the community and in different specialty clinics.
Gill, Jason M.R., Naveed Sattar, Alazawi, W, Gill, JMR, Sattar, N, Jason M. R. Gill, William Alazawi, Sattar, Naveed, Alazawi, William   +8 more
core   +1 more source

Technological Advances Are Associated With Better Clinical Outcomes of Percutaneous Coronary Intervention in Patients With Unprotected Left Main Disease

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Few large‐scale studies have evaluated the effectiveness of percutaneous coronary intervention (PCI) technological advances in the treatment of patients with unprotected left main coronary artery disease (LM‐CAD).
Dong Zhang, Ruohua Yan, Hao‐Yu Wang, Rui Zhang, Zhiyong Zhao, Guofeng Gao, Min Yang, Hao Wang, Shuai Liu, Rui Fu, Dong Yin, Chenggang Zhu, Lei Feng, Yuejin Yang, Kefei Dou   +14 more
doaj   +1 more source

A Facial Foundation Model for Clinical Biomarker Prediction and Real‐World Mobile Deployment

Advanced Science, EarlyView.
MedicalFaceFound is a facial foundation model developed through three‐stage progressive pre‐training, adapting representations from general vision to facial structure and clinical phenotypes. Using a single facial image, it estimates 62 biomarkers across multiple physiological systems and supports downstream risk prediction for cardiovascular ...
Tingfeng Xu, Huixuan Xu, Li Lin, Fei Wang, Yaodong Ding, Shuangqiao Liao, Xingyu Chen, Jichen Wen, Hongqiang Zhao, Jing Hao, Weixiang Zhao, Gong Zhang, Shiguang Shan, Yong Zeng, Hu Han, Minxian Wang   +15 more
wiley   +1 more source