Results 101 to 110 of about 4,979,977 (315)

General Practice Utilisation for Adults With Neurological Disability Who Are National Disability Insurance Scheme Participants in Australia

Australian Journal of Social Issues, EarlyView.
ABSTRACT Most adults with neurological disability rely on general practitioners for managing and preventing health complications. This study analysed patterns of general practice service utilisation among National Disability Insurance Scheme (NDIS) participants with neurological disability and compared these with people who are not NDIS participants ...
Stacey Oliver, Robin A. Ramme, Avinash Kondiboyina, Karina Gardner, Adam McLeod, Stephen Weeding, Christopher Pearce, Jacinta Douglas, Di Winkler   +8 more
wiley   +1 more source

activPAL and ActiGraph Assessed Sedentary Behavior and Cardiometabolic Health Markers [PDF]

, 2020
Purpose To establish whether associations between sedentary behavior and cardiometabolic health differ when assessed by thigh-worn and waist-worn accelerometry. Methods Participants were recruited from several areas in the United Kingdom.
JOSEPH HENSON, Edwardson, Charlotte L., KAMLESH KHUNTI, Biddle, Stuart J. H., Yates, Thomas, Khunti, Kamlesh, Davies, Melanie J., BENJAMIN MAYLOR, Maylor, Benjamin, CHARLOTTE L. EDWARDSON, STUART J. H. BIDDLE, THOMAS YATES, Henson, Joseph, MELANIE J. DAVIES   +13 more
core   +1 more source

A systematic, updated review of Xuezhikang, a domestically developed lipid-lowering drug, in the application of cardiovascular diseases

Acta Pharmaceutica Sinica B
Cardiovascular diseases (CVDs) are a major threat to public health globally. A large proportion of people with dyslipidaemia have poorly controlled lipid levels, emphasizing the need for alternative lipid-lowering treatments that are both effective and ...
Cheng Yang, Yongjian Wu, Jie Qian, Jian-Jun Li   +3 more
doaj   +1 more source

Aortic valve disease: Novel animal models for advancing our understanding of the underlying mechanisms

Animal Models and Experimental Medicine, EarlyView.
Due to the complex pathophysiology of aortic valve disease (AVD) and the resulting lack of effective pharmacotherapy, existing animal models are valuable research tools, but each has its own strengths and limitations. This review systematically surveys the major AVD models, compares their induction methods, pathological features, advantages and ...
Liya Hou, Xue Liu, Wangxing Hu, Xianbao Liu, Wei Zhu   +4 more
wiley   +1 more source

Importance of Genetic Studies of Cardiometabolic Disease in Diverse Populations [PDF]

, 2020
Genome-wide association studies have revolutionized our understanding of the genetic underpinnings of cardiometabolic disease. Yet, the inadequate representation of individuals of diverse ancestral backgrounds in these studies may undercut their ultimate
Below, J.E., Raffield, L.M., Wojcik, G.L., Petty, L.E., Fernández-Rhodes, L., Okello, S., Young, K.L., Lilly, A.G., North, K.E., Love, S.-A.M., Graff, M., Divaris, K., Highland, H.M., Agler, C.   +13 more
core   +1 more source

Plasma Proteome Reflects Tissue Damage and Clinical Manifestations in Patients With Inflammatory Myopathies

Arthritis &Rheumatology, EarlyView.
Objective Tissue‐specific biomarkers that are reliable and associated with clinical manifestations of idiopathic inflammatory myopathy (IIM) are lacking. The blood circulation in individuals serves as a central conduit, allowing communication between tissues and facilitating clearance and recycling of tissue‐derived proteins.
Yue‐Bei Luo, Josefin Kenrick, Angeles S. Galindo‐Feria, Antonella Notarnicola, Ana Daniela Ulloa Navas, Irene Peralta‐Garcia, Orane Demuynck, Andrea Kemp, Valérie Leclair, Karin Lodin, Eveline Van Gompel, Lara Dani, Fabricio Espinosa‐Ortega, Maryam Dastmalchi, Leonid Padyukov, Charlotta Preger, María Bueno Álvez, Mathias Uhlén, Peter Nilsson, Fredrik Edfors, Lina‐Marcela Diaz‐Gallo, Elisa Pin, Ingrid E. Lundberg, Begum Horuluoglu   +23 more
wiley   +1 more source

Prognostic impact of metformin in diabetic patients undergoing a percutaneous coronary intervention (PCI): protective effect is modified by procedural complexity

Cardiovascular Diabetology
Background Metformin, a widely prescribed glucose-lowering agent, has demonstrated cardiovascular benefits in patients with diabetes who do not have established atherosclerotic cardiovascular disease.
Zhihao Zheng, Ziyi Wang, Jining He, Yanjun Song, Weihua Song, Kefei Dou   +5 more
doaj   +1 more source

Precision nutrition for cardiometabolic diseases

Nature Medicine
Precision nutrition is a vibrant and rapidly evolving field of scientific research and innovation with the potential to deliver health, societal and economic benefits by improving healthcare delivery and policies. Advances in deep phenotyping technologies, digital tools and artificial intelligence have made possible early proof-of-concept research that
Guasch-Ferré, Marta, Wittenbecher, Clemens, Palmnas, Marie, Ben-Yacov, Orly, Dahm, Christina C., Fall, Tove, Heitmann, Berit L., Licht, Tine Rask, Löf, Marie, Loos, Ruth, Patel, Chirag, Quarta, Carmelo, Redman, Leanne M., Segal, Eran, Segata, Nicola, Snyder, Michael, Sun, Qi, Tobias, Deirdre, Hu, Frank B., Franks, Paul, Landberg, Rikard, Sargent, Jennifer, Merino, Jordi, Blaak, Ellen   +23 more
openaire   +5 more sources

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

Multiorgan, Multimodality Imaging in Cardiometabolic Disease

, 2017
Cardiometabolic disease, spanning conditions such as obesity to type 2 diabetes mellitus with excess cardiovascular risk, represents a major public health burden.
Willa A. Hsueh, Vidhya Kumar, Subha V. Raman   +2 more
core   +1 more source