Results 101 to 110 of about 153,127 (306)

Dusp6 deficiency attenuates neutrophil-mediated cardiac damage in the acute inflammatory phase of myocardial infarction

Nature Communications, 2022
Dusp6, an ERK specific phosphatase, was identified as a regenerative repressor during zebrafish heart regeneration. Here, the authors show that Dusp6 deficiency improves post infarctional cardiac repair by predominantly attenuating neutrophil-mediated ...
Xiaohai Zhou, Chenyang Zhang, Xueying Wu, Xinli Hu, Yan Zhang, Xuelian Wang, Lixia Zheng, Peng Gao, Jianyong Du, Wen Zheng, Haibao Shang, Keping Hu, Zhengfan Jiang, Yu Nie, Shengshou Hu, Rui-Ping Xiao, Xiaojun Zhu, Jing-Wei Xiong   +17 more
doaj   +1 more source

Study Protocol for a Stepped-Wedge Randomized Cookstove Intervention in Rural Honduras: Household Air Pollution and Cardiometabolic Health [PDF]

, 2019
Growing evidence links household air pollution exposure from biomass-burning cookstoves to cardiometabolic disease risk. Few randomized controlled interventions of cookstoves (biomass or otherwise) have quantitatively characterized changes in exposure ...
Africano, Sebastian, Benka-Coker, Megan L., Brook, Robert, Clark, Maggie L., Good, Nicholas, Keller, Joshua P., L\u27Orange, Christian, Nelson, Tracy L., Osorto Pinel, Anibal, Peel, Jennifer L., Quinn, Casey, Rajkumar, Sarah, Volckens, John, Walker, Ethan S., Weller, Zachary D., Young, Bonnie N.   +15 more
core   +1 more source

Changes in dietary patterns and body composition within 12 months of liver transplantation [PDF]

, 2016
Background: Cardiometabolic risk factors are increasing in liver transplant recipients (LTR). Influencing dietary factors have not been assessed. The aim of this observational study was to assess changes in weight, metabolic function, dietary intake and ...
Campbell, Katrina Louise, Fawcett, Jonathan, Hickman, Ingrid J., Jarrett, Maree, Lassemillante, Annie-Claude, Macdonald, Graeme A., McCoy, Simone M., Wallen, Matthew P.   +7 more
core   +1 more source

Ixekizumab With Tirzepatide Achieved Greater Disease Control Than Ixekizumab Alone in Adults With Psoriatic Arthritis and Overweight or Obesity: Results From a Randomized Clinical Trial

Arthritis &Rheumatology, EarlyView.
Objective Overweight or obesity is prevalent in 72% to 82% of individuals with psoriatic arthritis (PsA). We assessed the efficacy and safety of ixekizumab (IXE) concomitantly administered with tirzepatide (TZP) compared with IXE alone in adult participants with active PsA and overweight with at least one weight‐related comorbidity or obesity.
Joseph F. Merola, Philip Mease, Alan Kivitz, Naveed Sattar, Laura C. Coates, Daniel Aletaha, Cynthia E. Kartman, Peter Fischer, Luna Sun, Píndaro Martínez‐Osuna, Andris Kronbergs, Purvi Prajapati, Anabela Cardoso, Mark C. Genovese, Alexis Ogdie   +14 more
wiley   +1 more source

Maternal obesity has little effect on the immediate offspring but impacts on the next generation [PDF]

, 2013
Maternal obesity during pregnancy has been linked to an increased risk of obesity and cardiometabolic disease in the offspring, a phenomenon attributed to developmental programming. Programming effects may be transmissible across generations through both
Dakin, Rachel S., Drake, Amanda J., Hadoke, Patrick W. F., King, Vicky, Liu, Lincoln, Norman, Jane E., Seckl, Jonathan R., Walker, Brian R.   +7 more
core   +1 more source

Physical Fitness Profiles Among Children and Adolescents With ADHD and ASD: A Comparison With Typically Developing Peers

Autism Research, EarlyView.
ABSTRACT Children and adolescents with autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) often present physical and motor challenges that may compromise health, yet direct comparisons between these neurodevelopmental conditions and typically developing (TD) peers remain limited.
Nerea Blanco‐Martínez, Rocío Carballo‐Afonso, Joel Estévez‐Agudo, Carlos Ayán‐Pérez, José Carlos Diz‐Gómez   +4 more
wiley   +1 more source

A systematic, updated review of Xuezhikang, a domestically developed lipid-lowering drug, in the application of cardiovascular diseases

Acta Pharmaceutica Sinica B
Cardiovascular diseases (CVDs) are a major threat to public health globally. A large proportion of people with dyslipidaemia have poorly controlled lipid levels, emphasizing the need for alternative lipid-lowering treatments that are both effective and ...
Cheng Yang, Yongjian Wu, Jie Qian, Jian-Jun Li   +3 more
doaj   +1 more source

Sleep During Pregnancy: The nuMoM2b Pregnancy and Sleep Duration and Continuity Study [PDF]

, 2017
Study Objectives: To characterize sleep duration, timing and continuity measures in pregnancy and their association with key demographic variables. Methods: Multisite prospective cohort study. Women enrolled in the nuMoM2b study (nulliparous women
Basner, Robert C., Chung, Judith H., Facco, Francesca L., Grobman, William A., Haas, David M., Herbas, Marcos, Hunter, Shannon, Iams, Jay, Louis, Judette M., Manchanda, Shalini, Nhan-Chang, Chia-Lang, Parker, Corette B., Parry, Samuel, Pien, Grace W., Reid, Kathryn J., Saade, George R., Silver, Robert M., Simhan, Hyagriv N., Wing, Deborah A., Zee, Phyllis C.   +19 more
core   +1 more source

Functional foods and cardiometabolic diseases* International Task Force for Prevention of Cardiometabolic Diseases.

Nutrition, metabolism, and cardiovascular diseases : NMCD, 2014
Mounting evidence supports the hypothesis that functional foods containing physiologically-active components may be healthful. Longitudinal cohort studies have shown that some food classes and dietary patterns are beneficial in primary prevention, and this has led to the identification of putative functional foods.
Assmann G, Buono P, Daniele A, DELLA VALLE, Elisabetta, FARINARO, EDUARDO, Ferns G, Krogh V, Kromhout D, Masana L, Merino J, Misciagna G, PANICO, SALVATORE, RICCARDI, GABRIELE, RIVELLESE, ANGELA ALBAROSA, ROZZA, FRANCESCO, Salvatore F, Salvatore V, Stranges S, Trevisan M, TRIMARCO, BRUNO, Vetrani C.   +20 more
openaire   +5 more sources

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source