Results 111 to 120 of about 86,843 (267)

Food‐grade proteins, lipids, and fibers as potential tools to ameliorate cardiovascular disorders: A review

open access: yesFood Biomacromolecules, EarlyView.
Abstract Cardiovascular diseases (CVDs) remain the leading cause of global mortality, necessitating effective preventive and adjunct therapeutic strategies beyond conventional pharmacological interventions. Although previous reviews have focused on individual nutrients or dietary patterns, this review provides a mechanism‐based, integrative perspective
Sridevi Shanmugam   +7 more
wiley   +1 more source

Targeting vascular adhesion protein-1 and myeloperoxidase with a dual inhibitor SNT-8370 in preclinical models of inflammatory disease

open access: yesNature Communications
Inflammatory diseases are a major source of morbidity and mortality world-wide, the pathogenesis of which are characterised by the interplay of key pro-inflammatory and oxidative enzymes. Here, we report the development of a small molecule dual inhibitor
Elias Glaros   +8 more
doaj   +1 more source

Reconsidering the impact of saturated fat intake on metabolic health: A critical review of evidence and controversies

open access: yesFood Biomacromolecules, EarlyView.
Abstract Saturated fats (SFAs) play a complex role in health; therefore, their intake has been a topic of debate in the field of nutrition science. Therefore, this article emphasizes the importance of a balanced diet rather than SFA, considering genetic and metabolic differences, and advocates for the reconsideration of dietary guidelines based on the ...
Akash Kumar   +7 more
wiley   +1 more source

Cardiometabolic Diseases

open access: yesJACC: Basic to Translational Science, 2023
openaire   +1 more source

Walking the VLDL tightrope in cardiometabolic diseases

open access: yesTrends in Endocrinology & Metabolism
Very-low-density lipoprotein (VLDL), a triglyceride-rich lipoprotein secreted by hepatocytes, is pivotal for supplying peripheral tissues with fatty acids for energy production. As if walking on a tightrope, perturbations in the balance of VLDL metabolism contribute to cardiometabolic dysfunction, promoting pathologies such as cardiovascular disease ...
Mindy Kim, Ze Zheng
openaire   +3 more sources

Bioactive compounds in insects—Composition, extraction, functionality, food applications, and safety concerns

open access: yesFood Biomacromolecules, EarlyView.
This review synthesizes 94 studies (2000–2025) exploring edible insects as sustainable sources of peptides, lipids, and chitin. Utilizing “green” extraction, these bioactives offer antioxidant and antimicrobial benefits for functional foods. However, addressing safety concerns like allergenicity and heavy metals through standardized frameworks remains ...
Blessing Rachael Adeyeye   +1 more
wiley   +1 more source

Circulating Branched Chain Amino Acids and Cardiometabolic Disease

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Branched chain amino acids (BCAAs) are essential for protein homeostasis, energy balance, and signaling pathways. Changes in BCAA homeostasis have emerged as pivotal contributors in the pathophysiology of several cardiometabolic diseases, including type ...
Keenan S. Fine   +2 more
doaj   +1 more source

Lycopene‐rich food biomolecules from tomato processing waste: Green recovery, biopolymer‐based stabilisation, functional food applications and health relevance

open access: yesFood Biomacromolecules, EarlyView.
Abstract Tomato processing waste, particularly peel and pomace, is a sustainable and low‐cost source of lycopene‐rich food biomolecules. Lycopene, a lipophilic carotenoid with an extended conjugated structure, provides intense red colour, antioxidant potential and functional value to tomato‐derived ingredients.
Chandan Kumar Sahu, Mrinmoy Roy
wiley   +1 more source

Using a Biomarker of Biological Aging to Predict Incident Cardiometabolic Disease

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The ability to predict cardiometabolic risk is essential to support efforts to prevent future onset of disease. Biomarkers that assess biological aging—the rate of decline in physiological functioning that occurs across the systems of the ...
Kyle J. Bourassa   +8 more
doaj   +1 more source

Syncing Health Timing: Exploring the Interplay of Circadian Rhythms, Obesity, and Cardiovascular Diseases

open access: yesFood Safety and Health, EarlyView.
Circadian rhythm disruption impairs metabolic regulation, appetite control, and vascular function, promoting obesity and cardiovascular diseases. Evidence highlights a bidirectional relationship where metabolic disorders further disturb circadian timing.
Ghizal Fatima   +4 more
wiley   +1 more source

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