Results 11 to 20 of about 67,645 (203)

Cardiometabolic multimorbidity, genetic risk, and dementia: a prospective cohort study [PDF]

The Lancet. Healthy Longevity, 2022
Summary: Background: Individual cardiometabolic disorders and genetic factors are associated with an increased dementia risk; however, the relationship between dementia and cardiometabolic multimorbidity is unclear.
Xin You Tai, MBBS, Michele Veldsman, PhD, Donald M Lyall, PhD, Thomas J Littlejohns, PhD, Kenneth M Langa, ProfMD PhD, Masud Husain, ProfDPhil, Janice Ranson, PhD, David J Llewellyn, ProfPhD   +7 more
doaj   +5 more sources

Cardiometabolic multimorbidity, genetic risk and dementia

Alzheimer's & Dementia, 2022
BackgroundThe extent to which multiple cardiovascular and metabolic co-morbidity and genetic factors combine or interact to increase dementia risk is unknown.MethodWe analysed 435 105 participants from the UK Biobank prospective cohort of European ...
Janice M Ranson, Donald M Lyall, Veldsman, Michele, Tai, Xin You, Michele Veldsman, David J Llewellyn, Xin You Tai, Langa, Kenneth M, Llewellyn, David J, Kenneth M Langa, Masud Husain, Lyall, Donald M, Ranson, Janice M, Littlejohns, Thomas J, Thomas J Littlejohns, Husain, Masud   +15 more
core   +3 more sources

A multivariate genome-wide association study of psycho-cardiometabolic multimorbidity [PDF]

PLOS Genetics, 2023
Coronary artery disease (CAD), type 2 diabetes (T2D) and depression are among the leading causes of chronic morbidity and mortality worldwide. Epidemiological studies indicate a substantial degree of multimorbidity, which may be explained by shared ...
Pingault, Jean Baptiste, Choudhary, P., Jaervelin, M.R., Choudhary, Priyanka, Järvelin, Marjo Riitta, EarlyCause Consortium, Walton, E., Cecil, C.A.M., Sebert, Sylvain, Pingault, J.B., Milaneschi, Yuri, Järvelin, Marjo-Riitta, Penninx, B.W.J.H., ,, Walton, Esther, Pingault, Jean-Baptiste, Sebert, S., Baltramonaityte, Vilte, Cecil, Charlotte A.M., Cecil, Charlotte A M, Penninx, Brenda W J H, Felix, Janine, Milaneschi, Y., Penninx, Brenda W.J.H., Felix, J., Baltramonaityte, V.   +25 more
core   +4 more sources

Pregnancy loss and risk of cardiometabolic multimorbidity in Chinese women: the China Kadoorie Biobank study

BMC Public Health
Background While the association between pregnancy loss and individual cardiometabolic diseases (CMDs) is well-established, its impact on the risk of coexisting CMDs remains unclear.
Sha Huang, Siyu Zou, Jiayi Hee, Ruofan Gongye, Shunqing Xu, Kun Tang   +5 more
doaj   +2 more sources

Sequence Analysis of Cardiometabolic Multimorbidity and Association with Subsequent Dementia [PDF]

Innovation in Aging, 2023
Sequence analysis is used in the social sciences to examine patterns of events occurring across the life course, but there are few examples of its use in multimorbidity research among older adults.
Botoseneanu, Anda, Kaye, Jeffrey, Allore, Heather, Quinones, Ana, Nagel, Corey, Newsom, Jason, Bishop, Nicholas   +6 more
core   +2 more sources

Socio-geographical disparities in cardiometabolic multimorbidity in Sweden: an Intersectional Multilevel Analysis of Individual Heterogeneity and Discriminatory Accuracy (I-MAIHDA)

International Journal for Equity in Health
Background Mapping social and geographical disparities in health outcomes helps to identify vulnerable groups that should be targeted for intervention. This study aims to assess the disparities in cardiometabolic multimorbidity, the presence of at least ...
Kanya Anindya, Juan Merlo, Lars Lind, Lars Weinehall, Marcus Bendtsen, Tomas Jernberg, Maria Rosvall, Nawi Ng   +7 more
doaj   +2 more sources

Clinical, socioeconomic, and behavioural factors at age 50 years and risk of cardiometabolic multimorbidity and mortality: A cohort study. [PDF]

PLoS Medicine, 2018
BackgroundMultimorbidity is increasingly common and is associated with adverse health outcomes, highlighting the need to broaden the single-disease framework that dominates medical research.
Archana Singh-Manoux, Aurore Fayosse, Séverine Sabia, Adam Tabak, Martin Shipley, Aline Dugravot, Mika Kivimäki   +6 more
doaj   +4 more sources

Trends in the Prevalence of Cardiometabolic Multimorbidity in the United States, 1999–2018

International Journal of Environmental Research and Public Health, 2022
Cardiometabolic multimorbidity (co-existence of ≥1 cardiometabolic diseases) is increasingly common, while its prevalence in the U.S. is unknown. We utilized data from 10 National Health and Nutrition Examination Survey (NHANES) two-year cycles in U.S.
Tianqi Ma, Xunjie Cheng, Feiyun Ouyang, Guogang Zhang, Yongping Bai   +4 more
core   +3 more sources

Biological aging as a predictor of cardiometabolic multimorbidity [PDF]

Nature Cardiovascular Research
Recent analyses of observational data from 340,000 UK Biobank participants indicate that people with a higher biological age than their same-aged peers have an increased risk of developing cardiometabolic diseases. By contrast, the ability of accelerated
Kivimäki, M, Partridge, L
core   +4 more sources

Prevention and management of cardiometabolic multimorbidity in Canada

Background: Cardiometabolic multimorbidity, the diagnosis of ≥ 2 of stroke, heart disease and diabetes, is associated with a multiplicative mortality risk and numerous poor health outcomes.
Ketter, Nicole
core   +3 more sources