Weight gain among treatment-naïve persons with HIV starting integrase inhibitors compared to non-nucleoside reverse transcriptase inhibitors or protease inhibitors in a large observational cohort in the United States and Canada. [PDF]
IntroductionWeight gain following antiretroviral therapy (ART) initiation is common, potentially predisposing some persons with HIV (PWH) to cardio-metabolic disease.
Altoff, Keri N +23 more
core +1 more source
Measuring the burden of treatment for chronic disease: implications of a scoping review of the literature [PDF]
Background: Although there has been growing research on the burden of treatment, the current state of evidence on measuring this concept is unknown.
Mair, Frances S. +3 more
core +3 more sources
Impact of socioeconomic deprivation on rate and cause of death in severe mental illness [PDF]
Background: Socioeconomic status has important associations with disease-specific mortality in the general population. Although individuals with Severe Mental Illnesses (SMI) experience significant premature mortality, the relationship between ...
AC Phillips +47 more
core +2 more sources
Objective To determine the patterns of cardiometabolic multimorbidity and associated risk factors in sub-Saharan Africa (SSA).Design We used data from the WHO STEPwise approach to non-communicable disease risk factor surveillance cross-sectional surveys ...
Charles Agyemang +6 more
doaj +1 more source
Comorbidity and polypharmacy in chronic heart failure:a large cross-sectional study in primary care [PDF]
Background: Comorbidity is common in heart failure, but previous prevalence estimates have been based on a limited number of conditions using mainly non-primary care data sources.
Baron Franco, Bosco +5 more
core +3 more sources
Medication burden in the first 5 years following diagnosis of type 2 diabetes: findings from the ADDITION-UK trial cohort. [PDF]
INTRODUCTION: Individuals with screen-detected diabetes are likely to receive intensified pharmacotherapy to improve glycaemic control and general cardiometabolic health.
Black, James A +7 more
core +2 more sources
Multimorbidity, physical frailty, and self-rated health in older patients with atrial fibrillation
Background Holistic care models emphasize management of comorbid conditions to improve patient-reported outcomes in treatment of atrial fibrillation (AF).
Hawa O. Abu +10 more
doaj +1 more source
Prevalence and correlates of frailty in an older rural African population:findings from the HAALSI cohort study [PDF]
Background: Frailty is a key predictor of death and dependency, yet little is known about frailty in sub-Saharan Africa despite rapid population ageing. We describe the prevalence and correlates of phenotypic frailty using data from the Health and Aging ...
A Clegg +32 more
core +4 more sources
Combined healthy behaviors and healthcare services use in older adults [PDF]
Data on the combined impact of healthy behaviors on healthcare use in older adults are limited. Methods Study with community-dwelling individuals aged ≥60 years from the Spanish Seniors-ENRICA cohort, recruited in 2008–2010, followed through 2012–2013 ...
Banegas, José Ramón +5 more
core +1 more source
Chronic respiratory abnormalities in the multi-morbid frail elderly [PDF]
Two-thirds of people aged 65 65 years have multi-morbidity, with people living in the most deprived areas developing multi-morbidity 10-15 years even earlier.
Beghe', Bianca +2 more
core +1 more source

