Results 31 to 40 of about 4,004 (150)

Lifestyle factors and risk of multimorbidity of cancer and cardiometabolic diseases: a multinational cohort study

open access: yesBMC Medicine, 2020
Background Although lifestyle factors have been studied in relation to individual non-communicable diseases (NCDs), their association with development of a subsequent NCD, defined as multimorbidity, has been scarcely investigated.
Heinz Freisling   +52 more
doaj   +1 more source

Lifestyle Management in Menopause: A Systematic Review of Women With Premature Ovarian Insufficiency

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective Premature ovarian insufficiency (POI), the loss of ovarian function before age 40, increases the risk of cardiovascular disease, low bone mineral density, dementia and psychological distress. Lifestyle interventions reduce chronic disease risk in other populations and, with hormone therapy, may improve health outcomes in POI.
Ladan Yeganeh   +4 more
wiley   +1 more source

Similar multimorbidity patterns in primary care patients from two European regions: results of a factor analysis. [PDF]

open access: yesPLoS ONE, 2014
To compare the similarities among the multimorbidity patterns identified in primary care patients from two European regions (Spain and the Netherlands) with similar organisational features of their primary care systems, using validated methodologies.This
Beatriz Poblador-Plou   +5 more
doaj   +1 more source

PeakPASI as a marker of maximum psoriasis severity: a single‐center, cross‐sectional retrospective and questionnaire‐based study

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background The Psoriasis Area and Severity Index (PASI) is the standard measure for psoriasis severity but reflects only a single time point and may underestimate long‐term disease burden. To assess whether the highest‐ever recorded PASI (PeakPASI) can serve as a marker of historical disease severity and correlate with treatment burden and ...
Simran Wilkhoo   +6 more
wiley   +1 more source

Associations between cardiometabolic multimorbidity and cerebrospinal fluid biomarkers of Alzheimer’s disease pathology in cognitively intact adults: the CABLE study

open access: yesAlzheimer’s Research & Therapy
Background Cardiometabolic multimorbidity is associated with an increased risk of dementia, but the pathogenic mechanisms linking them remain largely undefined.
Qiong-Yao Li   +10 more
doaj   +1 more source

Cardiovascular‐Kidney‐Metabolic Syndrome: Conceptualising an Approach to Health Economic Modelling

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Cardiovascular‐kidney‐metabolic (CKM) syndrome has developed into a global public health crisis. Although integrated care is increasingly used to treat patients with CKM, current health economic models fail to capture the value of considering the CKM syndrome as a unified condition.
Volker Foos   +10 more
wiley   +1 more source

Tirzepatide for Obesity in Adults ≥ 65 Years: A Post Hoc Analysis of the SURMOUNT and SUMMIT Clinical Trials

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Tirzepatide is a once‐weekly glucagon‐like peptide‐1 (GLP‐1) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonist (RA) approved for weight management in adults with obesity. Data on older adults remain limited, however. This study aimed to examine tirzepatide's safety and efficacy in adults aged ≥ 65 years with obesity ...
Nasreen Alfaris   +6 more
wiley   +1 more source

Prospective association between plasma amino acids and three Multimorbidity patterns in older adults

open access: yesScientific Reports
The role of metabolomic profiling on different multimorbidity patterns remains unknown. This study aims to assess the prospective relationship between plasma concentrations of amino acids and three different multimorbidity patterns: musculoskeletal and ...
Grace Velapatiño-Gamarra   +7 more
doaj   +1 more source

Clinical and Economic Burden of Obesity and Cardiovascular Disease Among Medicare Fee‐For‐Service Beneficiaries

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims This retrospective cohort study described clinical outcomes, healthcare resource utilisation (HCRU), and costs among Medicare beneficiaries with or without obesity and stratified by cardiovascular disease (CVD) risk. Materials and Methods Using Medicare FFS claims (Jan 2016–Dec 2022), beneficiaries were indexed after 12 months of ...
Jiayin Xue   +9 more
wiley   +1 more source

Elevated blood remnant cholesterol and triglycerides are causally related to the risks of cardiometabolic multimorbidity

open access: yesNature Communications
The connection between triglyceride-rich lipoproteins and cardiometabolic multimorbidity, characterized by the concurrence of at least two of type 2 diabetes, ischemic heart disease, and stroke, has not been definitively established.
Yimin Zhao   +10 more
doaj   +1 more source

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