Results 51 to 60 of about 7,577 (211)
The Diabetes Remission Clinical Trial (DiRECT): protocol for a cluster randomised trial [PDF]
Background: Despite improving evidence-based practice following clinical guidelines to optimise drug therapy, Type 2 diabetes (T2DM) still exerts a devastating toll from vascular complications and premature death.
Adamson, Ashley +19 more
core +3 more sources
Chronic respiratory abnormalities in the multi-morbid frail elderly [PDF]
Two-thirds of people aged 65 65 years have multi-morbidity, with people living in the most deprived areas developing multi-morbidity 10-15 years even earlier.
Beghe', Bianca +2 more
core +1 more source
Continued efforts to translate diabetes cardiovascular outcome trials into clinical practice [PDF]
Diabetic patients suffer from a high rate of cardiovascular events and such risk increases with HbA1c. However, lowering HbA1c does not appear to yield the same benefit on macrovascular endpoints, as observed for microvascular endpoints. As the number of
Avogaro, Angelo +4 more
core +3 more sources
ObjectiveThis study aimed to explore the association between the Chinese visceral adiposity index (CVAI) and cardiometabolic multimorbidity in middle-aged and older Chinese adults.MethodsThe data used in this study were obtained from a national cohort ...
Xiaomei Ye +5 more
doaj +1 more source
Challenges in the care of familial hypercholesterolemia: a community care perspective [PDF]
Familial hyperchoelsterolaemia (FH) remains under-diagnosed and under-treated in the community setting. Earlier evidence suggested prevalence of 1:500 worldwide but newer evidence suggests it is more common.
Arnold-Reed, Diane +7 more
core +2 more sources
Background: In China, cancer accounts for one-fifth of all deaths, and exerts a heavy toll on patients, families, and society as a whole. Cardiometabolic multimorbidity (the presence of two or more cardiovascular and/or metabolic conditions) is a ...
Yang Zhao +3 more
doaj +1 more source
ABSTRACT Chronic diseases are the leading causes of morbidity and mortality worldwide and impose a substantial and long‐lasting burden on individuals, families, communities, and healthcare systems. In Australia, more than 47% of the population had at least one chronic condition in 2018, and the prevalence rose sharply with age: approximately 80% of ...
Getahun Kebede Beyera
wiley +1 more source
Accelerometer assessed moderate-to-vigorous physical activity and successful ageing: results from the Whitehall II study. [PDF]
Physical activity is key for successful ageing, but questions remain regarding the optimal physical activity pattern. We examined the cross-sectional association between physical activity and successful ageing using data on 3,749 participants (age rangeâ€
Elbaz, A +5 more
core +2 more sources
Sedentary Time Accumulated in Bouts is Positively Associated with Disease Severity in Fibromyalgia: The Al-andalus Project [PDF]
To examine the associations of prolonged sedentary time (ST) with disease severity in women with fibromyalgia, and to analyse the combined association of total ST and prolonged ST with the disease severity in this population. Women (n = 451; 51.3 +/- 7.6
Acosta Manzano, Pedro +5 more
core +6 more sources
Social determinants of multimorbidity patterns: A systematic review
Social determinants of multimorbidity are poorly understood in clinical practice. This review aims to characterize the different multimorbidity patterns described in the literature while identifying the social and behavioral determinants that may affect ...
Javier Álvarez-Gálvez +6 more
doaj +1 more source

