Results 71 to 80 of about 4,004 (150)

Obstructive Sleep Apnea: Epidemiology, Pathophysiology, Complications, Diagnosis, Management, and Emerging Fibrosis‐Linked Remodeling

MedComm, Volume 7, Issue 8, August 2026.
Obstructive sleep apnea (OSA) is characterized by recurrent upper‐airway collapse, which generates key nocturnal stressors including intermittent hypoxia, sleep fragmentation, intrathoracic pressure stress, and sympathetic activation. These physiological disturbances converge on shared biological mechanisms, including oxidative stress, inflammation ...
Nhi Ho Thi Thuy, Thị Hằng Giang Phan, Ali Hussein Eid, Paola Maccioccu, Stefania Camboni, Gavino Casu, Anna Maria Posadino, Roberta Giordo, Gianfranco Pintus   +8 more
wiley   +1 more source

Multimorbidity clusters and their association with secondary bacterial infections and disease severity among hospitalised COVID-19 patients in Victoria, Australia: Insights from population-wide linked data

Journal of Multimorbidity and Comorbidity
Background Limited evidence exists on how multimorbidity combinations influence the risk of secondary bacterial infections. This study identified multimorbidity clusters among hospitalised COVID-19 patients in Victoria (2020–2023) and examined their ...
Michael Muleme PhD, Mark Hayes MPH, Bridgette McNamara PhD, Naomi Clarke PhD, Eugene Athan PhD, Mohammad Akhtar Hussain PhD   +5 more
doaj   +1 more source

Identification, reliability, and validity of drug–drug interaction checkers in chronic diseases: A systematic review

British Journal of Pharmacology, Volume 183, Issue 16, Page 4532-4561, August 2026.
Abstract Drug–drug interactions (DDIs) pose major risks in chronic disease management where polypharmacy is common. Although digital DDI tools are used widely to aid healthcare professionals, tools rely on theoretical interactions. This limitation questions their reliability and validity for clinical relevancy.
Brayden Ng Gibson, Sri Chodapuneedi, Huan Yee Koh, Sugandha Gupta, Danijela Gasevic, Anna Yuanyuan Wang, Catia Marzolini, Saye Khoo, Lorena Romero, Lachlan Dalli, Jack Janetzki, Harvey Jia Wei Koh, Stella Talic   +12 more
wiley   +1 more source

Classification and Severity Assessment of Obesity in Clinical Risk Prediction of Multimorbidity Trajectories

Clinical Obesity, Volume 16, Issue 4, August 2026.
ABSTRACT Obesity is a key risk factor for chronic disease and multimorbidity, yet variation in how obesity is defined may influence risk estimation in clinical practise. Waist‐to‐hip ratio (WHR) and waist‐to‐height ratio (WHtR) are better at capturing fat distribution than body mass index (BMI) and may have a role in obesity related multimorbidity ...
Afua Ampadu‐Yeboah, Alistair Carr, Frederick Ho, Jason Gill, Naveed Sattar, Bhautesh Dinesh Jani   +5 more
wiley   +1 more source

Longitudinal sequencing of cardiometabolic multimorbidity among older adults and association with subsequent dementia onset.

PLoS ONE
BackgroundPatterns of development of cardiometabolic multimorbidity (CMM) and the impact of specific cardiometabolic disease combinations on cognitive function are not well understood.
Corey L Nagel, Siting Chen, Heather G Allore, Anda Botoseneanu, Jason T Newsom, Nick Bishop, David A Dorr, Jeffrey Kaye, Ana R Quiñones   +8 more
doaj   +1 more source

Association of Physical Activity With All‐Cause and CVD Mortality Across Metabolic and Obesity Phenotypes

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 7006-7017, August 2026.
ABSTRACT Aims To examine the independent and joint associations of metabolic status, obesity, and physical activity with all‐cause and cardiovascular disease (CVD) mortality across metabolic–obesity phenotypes. Materials and Methods We analysed 442 666 adults from the Korean National Health Insurance Service health screening cohort (2009–2012 ...
Yunmin Han, Younghwan Choi, Soomin Lee, Yeon Soo Kim   +3 more
wiley   +1 more source

Real‐World Effectiveness and 12‐Month Persistence of a Semaglutide‐Supported Digital Weight‐Loss Service: A Retrospective Cohort Study in Germany

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6985-6996, August 2026.
ABSTRACT Aim To evaluate the 12‐month effectiveness and patient persistence of a semaglutide‐supported digital weight‐loss service (DWLS) in a real‐world German cohort. Methods This retrospective study analysed 4535 patients who initiated the Juniper Germany DWLS. Primary endpoints included 12‐month medication and data submission adherence (receiving ≥ 
Louis Talay, Jason Hom, Marilyn Tan, Neera Ahuja   +3 more
wiley   +1 more source

Burden of Chronic Kidney Disease in Asia From 1990 to 2023: A Global Burden of Disease Study 2023

Nephrology, Volume 31, Issue 8, August 2026.
ABSTRACT Aim Despite growing recognition of chronic kidney disease (CKD) as a major health threat in Asia, its subregional variations are often overlooked. This study aimed to assess the CKD burden across five Asian subregions. Methods This study analysed data from the Global Burden of Disease Study 2023 to estimate the burden of CKD in Asia. CKD cases
Jungwon Chun, Dohwi Yun, Juyeong Kim, Hyunjee Kim, Yesol Yim, Yoon Lee, Dongjin Yeo, Selin Woo, Dong Keon Yon   +8 more
wiley   +1 more source

Determinants of Stress and Obstacles to Diabetes‐Related Quality of Life in Adults With Type 2 Diabetes: A Cross‐Sectional Interaction–Mediation Analysis

Worldviews on Evidence-Based Nursing, Volume 23, Issue 4, August 2026.
ABSTRACT Background Diabetes‐related quality of life (DR‐QoL) is shaped by interactions between cardiometabolic dysfunction and psychological stress, yet these mechanisms are rarely examined within a unified framework. Aims To evaluate the independent, interactive, and mediating effects of cardiometabolic factors and stress on DR‐QoL obstacles ...
Siti Fadlilah, Santi Damayanti, Maria Dyah Kurniasari, Shih Hsin Hsiao, Lee Kai Ling, Po Hao Feng, Hazel Novela Villagracia, Hsiu Ting Tsai   +7 more
wiley   +1 more source

Spatial Analysis of patterns of Multimorbidity in the Thai Cohort Study Using Latent Class Analysis

Journal of Epidemiology and Global Health
Objective The study aims to determine patterns of multimorbidity among common non-communicable diseases (NCDs) in Thailand. Study design Cross-sectional analysis.
Xiyu Feng, Haribondhu Sarma, Sam-ang Seubsman, Adrian Sleigh, Matthew Kelly   +4 more
doaj   +1 more source