Results 1 to 10 of about 2,327,467 (213)

Characterization of combined linagliptin and Y2R agonist treatment in diet-induced obese mice

Scientific Reports, 2021
Dipeptidyl peptidase IV (DPP-IV) inhibitors improve glycemic control by prolonging the action of glucagon-like peptide-1 (GLP-1). In contrast to GLP-1 analogues, DPP-IV inhibitors are weight-neutral.
Henrik H. Hansen, Rikke V. Grønlund, Tamara Baader-Pagler, Peter Haebel, Harald Tammen, Leif Kongskov Larsen, Jacob Jelsing, Niels Vrang, Thomas Klein   +8 more
doaj   +1 more source

The value of the MIND diet in the primary and secondary prevention of hypertension: A cross-sectional and longitudinal cohort study from NHANES analysis

Frontiers in Nutrition, 2023
BackgroundThe Mediterranean-Dietary Approaches to Stop Hypertension for neurodegenerative delay (MIND) has been regarded as a novel healthy dietary pattern with huge benefits.
Yanjun Song, Yanjun Song, Yanjun Song, Zhen'ge Chang, Kongyong Cui, Kongyong Cui, Kongyong Cui, Chenxi Song, Chenxi Song, Chenxi Song, Zhongxing Cai, Zhongxing Cai, Zhongxing Cai, Boqun Shi, Boqun Shi, Boqun Shi, Qiuting Dong, Qiuting Dong, Qiuting Dong, Kefei Dou, Kefei Dou, Kefei Dou   +21 more
doaj   +1 more source

Longitudinal association of epicardial and thoracic adipose tissues with coronary and cardiac characteristics in psoriasis

Heliyon, 2023
Background: s: Psoriasis is a disease of systemic inflammation associated with increased cardiometabolic risk. Epicardial adipose tissue (EAT) and thoracic adipose tissue (TAT) are contributing factors for atherosclerosis and cardiac dysfunction.
Ross O'Hagan, Li-Yueh Hsu, Haiou Li, Christin G. Hong, Philip M. Parel, Alexander R. Berg, Grigory A. Manyak, Vy Bui, Nidhi H. Patel, Elizabeth M. Florida, Heather L. Teague, Martin P. Playford, Wunan Zhou, Damini Dey, Marcus Y. Chen, Nehal N. Mehta, Alexander V. Sorokin   +16 more
doaj   +1 more source

Three-dimensional morphometric analysis reveals time-dependent structural changes in microglia and astrocytes in the central amygdala and hypothalamic paraventricular nucleus of heart failure rats

Journal of Neuroinflammation, 2020
Background Cardiovascular diseases, including heart failure, are the most common cause of death globally. Recent studies support a high degree of comorbidity between heart failure and cognitive and mood disorders resulting in memory loss, depression, and
Ferdinand Althammer, Hildebrando Candido Ferreira-Neto, Myurajan Rubaharan, Ranjan K. Roy, Atit A. Patel, Daniel N. Cox, Javier E. Stern   +6 more
doaj   +1 more source

Correction to: Three-dimensional morphometric analysisreveals time-dependent structural changesin microglia and astrocytes in the centralamygdala and hypothalamicparaventricular nucleus of heart failure rats

Journal of Neuroinflammation, 2020
An amendment to this paper has been published and can be accessed via the original article.
Ferdinand Althammer, Hildebrando Candido Ferreira-Neto, Myurajan Rubaharan, Ranjan K. Roy, Atit A. Patel, Anne Murphy, Daniel N. Cox, Javier E. Stern   +7 more
doaj   +1 more source

High absolute neutrophil count with type 2 diabetes is associated with adverse outcome in patients with coronary artery disease: A large-scale cohort study

Frontiers in Endocrinology, 2023
BackgroundInflammatory processes crucially modulate the development, progression, and outcomes of coronary artery disease (CAD). Since hyperglycemia could alter inflammatory responses, this study aimed to investigate the effect of ANC, a novel and ...
Jining He, Jining He, Zhangyu Lin, Zhangyu Lin, Chenxi Song, Chenxi Song, Rui Zhang, Rui Zhang, Haoyu Wang, Haoyu Wang, Sheng Yuan, Sheng Yuan, Xiaohui Bian, Xiaohui Bian, Qiuting Dong, Kefei Dou, Kefei Dou   +16 more
doaj   +1 more source

Estimated sdLDL-C for predicting high-risk coronary plaque features in psoriasis: a prospective observational study

Lipids in Health and Disease, 2023
Background Psoriasis (PSO) is a skin disorder with systemic inflammation and high coronary artery disease risk. A distinct lipid phenotype occurs in psoriasis, which is characterized by high plasma triglycerides (TGs) with typically normal or even low ...
Alexander V. Sorokin, Nidhi Patel, Haiou Li, Christin G. Hong, Maureen Sampson, Ross O’Hagan, Elizabeth M. Florida, Heather L. Teague, Martin P. Playford, Marcus Y. Chen, Nehal N. Mehta, Alan T. Remaley   +11 more
doaj   +1 more source

The association of procedural variables and lipid parameters with coronary rotational atherectomy outcomes

Reviews in Cardiovascular Medicine, 2021
The aim of our study is to evaluate the association of rotational atherectomy (RA) operation procedural indices and baseline lipid parameters with the prognosis of the patients with severe coronary calcification who underwent RA.
Shuang Zhang, Wen-Jia Zhang, Hui-Wei Shi, Zhi-Fan Li, Yong-Gang Sui, Jie Qian, Na-Qiong Wu   +6 more
doaj   +1 more source

Association Between MIND Diet Adherence and Mortality: Insights from Diabetic and Non-Diabetic Cohorts

Nutrition & Diabetes, 2023
Background/Objectives To date, evidence regarding the protective roles of the Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) diet in patients with type 2 diabetes mellitus (T2DM) is scarce.
Yanjun Song, Zhen’ge Chang, Chenxi Song, Kongyong Cui, Boqun Shi, Rui Zhang, Qiuting Dong, Kefei Dou   +7 more
doaj   +1 more source

Development of novel ultra-sensitive IL-11 target engagement assays to support mechanistic PK/PD modeling for an anti-IL-11 antibody therapeutic

mAbs, 2022
An in-house antibody generation campaign identified a diverse, high affinity set of anti-interleukin-11 (IL-11) monoclonal antibodies (mAbs) to enable successful development of novel, custom ultra-sensitive target engagement assays for detection of “free”
Maria Myzithras, Siqi Lin, Legairre Radden, Cynthia Hess Kenny, Zheng Cai, Angus MacDonald, Ralph Binetti, Michael Marlow, Paul Fracasso, Glenn Gibson, Christina Bartlett, Julie Hawkins, Steven Hansel   +12 more
doaj   +1 more source