Results 21 to 30 of about 10,604,379 (306)
Calpain and Cardiometabolic Diseases
International Journal of Molecular Sciences, 2023 Calpain is delineated as a superfamily of cysteine proteases containing a CysPC motif within their genes. Among the fifteen species of mammalian homologs, calpain-1 and -2, which are categorized as conventional isozymes, execute limited proteolysis in a calcium-dependent fashion.
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The Lancet Regional Health - Europe, 2023 Summary Background It is currently unknown whether ultra-processed foods (UPFs) consumption is associated with a higher incidence of multimorbidity. We examined the relationship of total and subgroup consumption of UPFs with the risk of multimorbidity ...
R. Córdova +34 more
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Inflammatory markers and cardiometabolic diseases [PDF]
Acta Clinica Belgica, 2015 A growing body of evidence emerges that obesity, metabolic syndrome, type 2 diabetes and cardiovascular disease are intimately related to chronic inflammation.A narrative review summarizing the most recent data of the literature describing the pathological implications of inflammation in obese patients with cardiometabolic disorders.Besides high ...
ESSER, Nathalie +2 more
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Lipids in Health and Disease, 2023 Background Psoriasis (PSO) is a skin disorder with systemic inflammation and high coronary artery disease risk. A distinct lipid phenotype occurs in psoriasis, which is characterized by high plasma triglycerides (TGs) with typically normal or even low ...
Alexander V. Sorokin +11 more
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Nature Communications, 2023 Blood metabolome is commonly used in human studies to explore the associations of gut microbiota-derived metabolites with cardiometabolic diseases. Here, in a cohort of 1007 middle-aged and elderly adults with matched fecal metagenomic (149 species and ...
Kui Deng +12 more
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JAMA pediatrics, 2023 Importance Although the increased risk of obesity among individuals with autism has been well established, evidence on the association between autism, cardiometabolic disorders, and obesity remains inconclusive.
Chathurika S. Dhanasekara +9 more
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The Role of Oxidative Stress Enhanced by Adiposity in Cardiometabolic Diseases
International Journal of Molecular Sciences, 2023 Cardiometabolic diseases (CMDs), including cardiovascular disease (CVD), metabolic syndrome (MetS), and type 2 diabetes (T2D), are associated with increased morbidity and mortality.
I. Świątkiewicz +5 more
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CaMKII in Cardiometabolic Disease
Aging, 2014 The worldwide epidemic of obesity is closely linked to insulin resistance and type 2 diabetes (T2D), which have led to a critical need for new drug development. Insulin resistance and T2D contribute to the pathogenesis of many diseases including fatty liver disease, cardiovascular disease, kidney failure and retinal disease.
Lale, Ozcan, Ira, Tabas
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Nature Communications, 2023 Different location of adipose tissue may have different consequences to cardiometabolic risk. Here the authors report that deep learning enabled accurate prediction of specific adipose tissue volumes, and that after adjustment for BMI, visceral adiposity
Saaket Agrawal +11 more
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Racial/Ethnic Discrimination and Cardiometabolic Diseases: A Systematic Review
Journal of Racial and Ethnic Health Disparities, 2023 Introduction Racial discrimination has been identified as a risk factor for cardiometabolic diseases, the leading cause of morbidity and mortality among racial/ethnic minority groups; however, there is no synthesis of current knowledge on the association
Osayande Agbonlahor +5 more
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