Results 111 to 120 of about 146,242 (308)

Long‐term impact of Elexacaftor/Tezacaftor/ivacaftor on pulmonary, nutritional and metabolic outcomes in homozygous F508del cystic fibrosis patients: A real‐world cohort study

British Journal of Clinical Pharmacology, EarlyView.
Aim Elexacaftor/tezacaftor/ivacaftor (ETI) has markedly improved cystic fibrosis (CF) outcomes. However, its long‐term impact on nutrition, metabolism and liver health remains underexplored. We assessed 30‐month changes in pulmonary, nutritional, metabolic and inflammatory markers in people with CF (PwCF) homozygous for F508del.
Nicola Perrotta, Luigi Angelo Fiorito, Roberta Vescovo, Anna Virgilio, Giulia Amato, Giuseppe Cimino   +5 more
wiley   +1 more source

Sedentary behaviors and adiposity in young people: causality and conceptual model [PDF]

, 2018
Research on sedentary behavior and adiposity in youth dates back to the 1980s. Sedentary behaviors, usually screen time, can be associated with adiposity.
Biddle, Stuart J. H., Pearson, Natalie, Salmon, Jo   +2 more
core   +3 more sources

Comparative efficacy of GLP‐1 RA, tirzepatide and SGLT‐2 inhibitors in metabolic liver disease: A network meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aim Metabolic liver disease, including nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis, is a major cause of chronic liver dysfunction worldwide, creating an urgent need for effective treatments. This systematic literature review (SLR) and network meta‐analysis (NMA) systematically reviews and compares the efficacy and safety ...
Andrej Belančić, Christina Antza, Anastasios Poutachidis, Smaro Palaska, Elvira Meni Maria Gkrinia, Andrea Katrin Faour, Yusuf Ziya Sener, Seher Sener, Rehena Sultana   +8 more
wiley   +1 more source

Cardiometabolic Risk Factors and Cardiovascular Risk in Hidradenitis Suppurativa

JAMA Dermatology
This cohort study examines the association between severity of hidradenitis suppurativa and cardiovascular risk.
Dons, Maria, Dempsey, Alison, Carlucci, Philip M., Shankar, Shruthi, Parameswaran, Anupama, Weber, Brittany N., Garshick, Michael S.   +6 more
openaire   +2 more sources

Contemporary Startegies for Managing Cardiometabolic Risk Factors [PDF]

Journal of Managed Care Pharmacy, 2006
To review the metabolic syndrome as defined by the 2001 Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (ATP III) and its modifiable risk factors and to review currently available treatment modalities.Metabolic syndrome, although still controversial, is a growing concern.
openaire   +2 more sources

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad, Anshu Arora, Arun Arora, Jeena Vaid, Arif Khan   +4 more
wiley   +1 more source

Cardiometabolic risk stratification in pediatric obesity: evaluating the clinical utility of fasting insulin and BMI-SDS

Cardiovascular Diabetology
Background Patients with obesity during childhood have an increased risk of fatal and non-fatal cardiovascular events during adulthood. The severity of obesity is commonly determined by BMI.
Rasmus Stenlid, Sami El Amrani, Sara Y. Cerenius, Banu K. Aydin, Hannes Manell, Katharina Mörwald, Julia Lischka, Julian Gomahr, Thomas Pixner, Iris Ciba, Stefan K. James, Anders Forslund, Daniel Weghuber, Peter Bergsten   +13 more
doaj   +1 more source

Cardiometabolic risk factors in bank employees

National Journal of Physiology, Pharmacy and Pharmacology, 2015
Background: Coronary heart disease and type 2 diabetes mellitus (T2DM) are preceded by a cluster of metabolic risk factors that include hypertension, dyslipidemia, and prediabetes. The prevalence of these metabolic risk factors shows an upward trend with
Onkar Singh, Mrityunjay Gupta, Vijay Khajuria   +2 more
doaj   +1 more source

Screen time is associated with adiposity and insulin resistance in children [PDF]

, 2017
Higher screen time is associated with type 2 diabetes (T2D) risk in adults, but the association with T2D risk markers in children is unclear. We examined associations between self-reported screen time and T2D risk markers in children.
Cook, Derek G., Donin, Angela S., Nightingale, Claire M., Owen, Christopher G., Rudnicka, Alicja R., Sattar, Naveed, Whincup, Peter H.   +6 more
core   +1 more source

Insomnia as a Cardiometabolic Risk Factor [PDF]

Sleep, 2013
Michael A, Grandner, Michael L, Perlis
openaire   +2 more sources