Results 121 to 130 of about 146,242 (308)

Anti‐Obesity Pharmacotherapy and Emerging Multimodal Interventions for Obstructive Sleep Apnea

Chronic Diseases and Translational Medicine, EarlyView.
Cellular and molecular mechanisms of obesity‐related obstructive sleep apnea (OSA). ADMA: asymmetric dimethyrarginine, NLRP3: nucleotide‐binding domain, leucine‐rich repeat family, Pyrin domain containing 3, TLR: toll‐like receptors, IL‐1β: interleukin‐1β, IL‐6: interleukin‐6; LPS: lipopolysacharide, ROS: reactive oxygen species, TNF‐α.
Anish Preshy, Cornelius J. Fernandez, Mohammad Hamid Nedai, Joseph M. Pappachan   +3 more
wiley   +1 more source

Influence of cardiorespiratory fitness and physical activity levels on cardiometabolic risk factors during menopause transition: A MONET study

Preventive Medicine Reports, 2016
To determine the influence of cardiorespiratory fitness (hereafter “fitness”) and physical activity levels on cardiometabolic risk factors in premenopausal women going through the menopause transition.
Joseph Abdulnour, Sahar Razmjou, Éric Doucet, Pierre Boulay, Martin Brochu, Rémi Rabasa-Lhoret, Jean-Marc Lavoie, Denis Prud'homme   +7 more
doaj   +1 more source

The Placental Transcriptome in Late Gestational Hypoxia Resulting in Murine Intrauterine Growth Restriction Parallels Increased Risk of Adult Cardiometabolic Disease. [PDF]

, 2019
Intrauterine growth restriction (IUGR) enhances risk for adult onset cardiovascular disease (CVD). The mechanisms underlying IUGR are poorly understood, though inadequate blood flow and oxygen/nutrient provision are considered common endpoints.
Casero, David, Chu, Alison, Cosi, Amy, Devaskar, Sherin U, Thamotharan, Shanthie, Wadehra, Madhuri   +5 more
core   +2 more sources

The Epidemiological Landscape and Burden of Chronic Disease in Australia: Contextualizing the Distinct Profile of Tasmania

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Chronic diseases are the leading causes of morbidity and mortality worldwide and impose a substantial and long‐lasting burden on individuals, families, communities, and healthcare systems. In Australia, more than 47% of the population had at least one chronic condition in 2018, and the prevalence rose sharply with age: approximately 80% of ...
Getahun Kebede Beyera
wiley   +1 more source

GLP‐1 Receptor Agonists in Metabolic Dysfunction‐Associated Steatotic Liver Disease: Bridging Hepatic and Cardiovascular Outcomes

Chronic Diseases and Translational Medicine, EarlyView.
Endogenous GLP‐1 and exogenous GLP‐1 RAs activate GLP‐1R‐expressing vagal afferents in the portal vein, projecting to the nucleus tractus solitarius (NTS). This input engages brainstem–hypothalamic circuits that regulate metabolic homeostasis. Hypothalamic efferent vagal output to the liver suppresses lipogenesis, enhances triglyceride export, and ...
Gabriel Amorim Moreira Alves, Masatoki Teranishi, Rajendranandini Majumdar, Fazal Khan, Mohan Dodeja, Ana Claudia Teixeira de Castro Gonçalves Ortega, Marco Acerboni, Arosh S. Perera Molligoda Arachchige, Frank James   +8 more
wiley   +1 more source

Tracking of device-measured sedentary time, cardiorespiratory fitness, and cardiometabolic risk factors from childhood to young adulthood

American Journal of Preventive Cardiology
Background: The tracking of clustered cardiometabolic risk from childhood to young adulthood, i.e., whether an unfavourable cardiometabolic risk profile persists from childhood into young adulthood, remain uncertain and has previously not included ...
Anders Husøy, Elin Kolle, Jostein Steene-Johannessen, Lars Bo Andersen, Ulf Ekelund, Sigmund Alfred Anderssen   +5 more
doaj   +1 more source

Polygenic risk score for Alzheimer’s disease and trajectories of cardiometabolic risk factors in children [version 1; peer review: 2 approved]

Wellcome Open Research, 2019
Introduction: Cardiometabolic factors are implicated in the aetiology of Alzheimer’s disease and may lie on the pathways linking genetic variants to Alzheimer’s disease across the life course.
Roxanna Korologou-Linden, Linda O'Keeffe, Laura D. Howe, George Davey-Smith, Hannah J. Jones, Emma L. Anderson, Evie Stergiakouli   +6 more
doaj   +1 more source

Cardiometabolic health in students and young adults with mild/moderate intellectual disabilities : results from a longitudinal follow-up study and a school intervention [PDF]

, 2013
Background Adults with intellectual disabilities (ID) develop the metabolic syndrome and cardiovascular disease more frequently than individuals without ID.
Flygare Wallén, Eva
core   +1 more source

Muscle Carnosine Is Associated with Cardiometabolic Risk Factors in Humans

PLOS ONE, 2015
Carnosine is a naturally present dipeptide abundant in skeletal muscle and an over-the counter food additive. Animal data suggest a role of carnosine supplementation in the prevention and treatment of obesity, insulin resistance, type 2 diabetes and cardiovascular disease but only limited human data exists.Samples of vastus lateralis muscle were ...
B. De Courten, T. Kurdiova, M. P. J. De Courten, V. Belan, I. Everaert, M. Vician, H. Teede, D. Gasperikova, G. Aldini, W. Derave, J. Ukropec, B. Ukropcova, C. Moro   +12 more
openaire   +7 more sources

LEADER 5: prevalence and cardiometabolic impact of obesity in cardiovascular high-risk patients with type 2 diabetes mellitus: baseline global data from the LEADER trial [PDF]

, 2016
Background: Epidemiological data on obesity are needed, particularly in patients with type 2 diabetes mellitus (T2DM) and high cardiovascular (CV) risk.
A Collier, A Goyal, A Ludman, A. Comlekci, AE Sumner, American Diabetes Association, American Diabetes Association, BA Swinburn, BM Scirica, C Daousi, CJ Lavie, CJ Li, D Wormser, E Selvin, E. Franek, EA Molenaar, Expert Panel on Detection, F. M. M. Baeres, I Chopra, I. Raz, ID Caterson, IM Rückert, J Logue, J. Petrie, J. Vidal, JB Albu, K Niswender, KG Alberti, L Blonde, L Guenette, L. A. Leiter, L. Masmiquel, L. van Gaal, LA Vázquez, LG Goh, LN McEwen, M Bastien, M Leenders, M Ng, M. Eriksson, MA Bethel, MD Jensen, ME Farkouh, MJ Davies, NJ Stone, NR Jones, P Li, P Weeke, RR Wing, S Baxi, S. Bain, S. Jacob, S. P. Marso, SK Paul, SP Marso, T Tillin, The Emerging Risk Factors Collaboration, UE Ntuk, V Bhan, X Pi-Sunyer   +59 more
core   +2 more sources