Results 141 to 150 of about 801,889 (178)
Long Noncoding RNA CPR (Cardiomyocyte Proliferation Regulator) Regulates Cardiomyocyte Proliferation and Cardiac Repair [PDF]
Circulation, 2019 Background: The adult mammalian cardiomyocytes lose their proliferative capacity, which is responsible for cardiac dysfunction and heart failure following injury. The molecular mechanisms underlying the attenuation of adult cardiomyocyte proliferation remain largely unknown. Because long noncoding RNAs (lncRNAs) have a critical
Murugavel Ponnusamy +2 more
exaly +3 more sources
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Cardiomyocyte Proliferation for Therapeutic Regeneration
Current Cardiology Reports, 2018Current pharmacologic treatments for cardiovascular disease do not correct the underlying cellular defect, the loss of cardiomyocytes. With recent advancements in cardiac regenerative approaches, the induction of endogenous mature cardiomyocyte proliferation has emerged as a new possibility.
John P, Leach, James F, Martin
openaire +2 more sources
Extra- and Intracellular Factors Regulating Cardiomyocyte Proliferation in Postnatal Life.
Cardiovascular Research, 2014 One of the striking differences that distinguish the adult from the embryonic heart in mammals and set it apart from the heart in urodeles and teleosts is the incapacity of cardiomyocytes to respond to damage by proliferation. While the molecular reasons
Serena Zacchigna, Mauro Giacca
exaly +2 more sources
Cardiomyocyte cytokinesis score: a potential method for cardiomyocyte proliferation
Cell Biology International, 2014AbstractOne of the most important indicators of myocardial regeneration is cardiomyocyte proliferation. However, it is difficult to distinguish cardiomyocytes in the regenerating stage from binucleated or multinucleated myocytes by conventional morphometric techniques.
Kun, Hua +4 more
openaire +2 more sources
Factors Affecting the Proliferation Ability of Cardiomyocytes
2020 7th International Conference on Biomedical and Bioinformatics Engineering, 2020Heart disease is a highly lethal disease that causes a large number of deaths worldwide every year. When heart disease happened, it will cause the death of a large number of cardiomyocytes. Because of the proliferation capacity of mammalian cardiomyocytes is limited, it's unable for cardiomyocytes to compensate the damage through their own ...
openaire +2 more sources
Circulation Research, 2011
Cardiomyocytes derived from embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) are promising cell sources for cardiac regeneration. Previously, we established a novel systematic cardiovascular cell induction system with mouse ESCs and iPSCs.
Hideki Uosaki, Jun K Yamashita
openaire +1 more source
Cardiomyocytes derived from embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) are promising cell sources for cardiac regeneration. Previously, we established a novel systematic cardiovascular cell induction system with mouse ESCs and iPSCs.
Hideki Uosaki, Jun K Yamashita
openaire +1 more source
Cardiomyocyte proliferation by calcineurin inhibition
Nature Cardiovascular Research, 2022Hirofumi Watanabe, Henry M. Sucov
openaire +2 more sources
Mechanisms to Induce Cardiomyocyte Proliferation
2021Endogenous mechanisms for renewal of adult cardiomyocytes (CMs) are insufficient for repair of extensive injury to the myocardium as adult CMs have limited capacity for proliferation. Several recent studies suggest that latent regenerative potential in the adult heart can be exploited and that in the injured heart, regeneration can be induced by ...
openaire +1 more source
Cardiomyocyte‐derived exosomes promote cardiomyocyte proliferation and neonatal heart regeneration
The FASEB JournalAbstract Heart regeneration was mainly achieved by intrinsic capacity. Exosomes are crucial in cardiovascular disease, yet their involvement in myocardial regeneration remains underexplored. To understand the role of cardiomyocyte‐derived exosomes (CM‐Exos) in heart regeneration.
Jielei Gu +12 more
openaire +2 more sources
Cardiomyocyte proliferation and reprogramming for cardiac regeneration
Journal of Molecular and Cellular Cardiology, 2023Li, Qian, Bin, Zhou, Huang-Tian, Yang
openaire +2 more sources