Results 31 to 40 of about 296,757 (381)

Targeting lipid metabolism as a new therapeutic strategy for inherited cardiomyopathies

Frontiers in Cardiovascular Medicine, 2023
Inherited cardiomyopathies caused by pathological genetic variants include multiple subtypes of heart disease. Advances in next-generation sequencing (NGS) techniques have allowed for the identification of numerous genetic variants as pathological ...
Karen R. Gaar-Humphreys, Karen R. Gaar-Humphreys, Alyssa van den Brink, Alyssa van den Brink, Mark Wekking, Mark Wekking, Folkert W. Asselbergs, Folkert W. Asselbergs, Frank G. van Steenbeek, Frank G. van Steenbeek, Frank G. van Steenbeek, Magdalena Harakalova, Magdalena Harakalova, Magdalena Harakalova, Jiayi Pei, Jiayi Pei, Jiayi Pei   +16 more
doaj   +1 more source

The Relationship of Left Ventricular Trabeculation to Ventricular Function and Structure Over a 9.5-Year Follow-Up The MESA Study [PDF]

, 2014
Left ventricular (LV) trabeculation is highly variable among individuals and is increased in some diseases (e.g., congenital heart disease or cardiomyopathies), but its significance in population-representative individuals is ...
Anand, Aras, Axel, Bettari, Bild, Bluemke, Captur, David A. Bluemke, Dawson, Doughty, Filip Zemrak, Freedom, Gabriella Captur, Jacquier, James C. Moon, João A.C. Lima, Kawel, Kohli, Lipicky, Liu, Mark A. Ahlman, Martin R. Prince, Nadine Kawel-Boehm, Natori, Oechslin, Petersen, Petersen, Ritter, Saidi A. Mohiddin, Stanton, Steffen E. Petersen, Stähli, William G. Hundley, Wong   +33 more
core   +1 more source

Cost-effectiveness of eplerenone in patients with systolic heart failure and mild symptoms [PDF]

, 2014
Aim In the Eplerenone in Mild Patients Hospitalization and Survival Study in Heart Failure (EMPHASIS-HF), aldosterone blockade with eplerenone decreased mortality and hospitalisation in patients with mild symptoms (New York Heart Association class II ...
Akehurst, R., Cowie, M.R., Krum, H., Lee, D., McMurray, J.J.V., Pitt, B., van Veldhuisen, D.J., Vincent, J., Wilson, K., Zannad, F.   +9 more
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The role of cardiac troponin T quantity and function in cardiac development and dilated cardiomyopathy [PDF]

, 2008
Background: Hypertrophic (HCM) and dilated (DCM) cardiomyopathies results from sarcomeric protein mutations, including cardiac troponin T (cTnT, TNNT2).
Ahmad, F, Banerjee, SK, Conner, DA, Huang, XN, Janczewski, AM, Keller, BB, Lage, ML, Mathier, MA, Moskowitz, IP, Perez-Atayde, AR, Rager, J, Saba, S, Seidman, CE, Seidman, JG, Shroff, SG, Smith, SH, Tinney, JP, Tobita, K   +17 more
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Classification of the cardiomyopathies: a position statement from the European Society Of Cardiology Working Group on Myocardial and Pericardial Diseases.

European Heart Journal, 2007
In biology, classification systems are used to promote understanding and systematic discussion through the use of logical groups and hierarchies. In clinical medicine, similar principles are used to standardise the nomenclature of disease.
P. Elliott, B. Andersson, E. Arbustini, Z. Bilińska, F. Cecchi, P. Charron, O. Dubourg, U. Kühl, B. Maisch, W. McKenna, L. Monserrat, S. Pankuweit, C. Rapezzi, P. Seferovic, L. Tavazzi, A. Keren   +15 more
semanticscholar   +1 more source

A rare case report of hypertrophic cardiomyopathy induced by catecholamine-producing tumor [PDF]

, 2018
RATIONALE: Catecholamine-producing tumors are rare, occurring in less than 0.2% of patients with hypertension, but can have relevant cardiovascular morbidity and mortality. PATIENT CONCERNS: A 37-year-old woman presented with a history of dyspnea, chest
Bisogni, Valeria, Bonvicini, Maria, Ciardi, Antonio, Concistré, Antonio, De Toma, Giorgio, Frustaci, Andrea, Iannucci, Gino, Letizia, Claudio, Mezzadri, Martina, Oliviero, Gaia, Olmati, Federica, Petramala, Luigi, Saracino, Vincenza   +12 more
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Targeted therapies in genetic dilated and hypertrophic cardiomyopathies: from molecular mechanisms to therapeutic targets. A position paper from the Heart Failure Association (HFA) and the Working Group on Myocardial Function of the European Society of Cardiology (ESC)

European Journal of Heart Failure, 2021
Genetic cardiomyopathies are disorders of the cardiac muscle, most often explained by pathogenic mutations in genes encoding sarcomere, cytoskeleton, or ion channel proteins.
Rudolf A. Boer, S. Heymans, J. Backs, L. Carrier, A. Coats, S. Dimmeler, T. Eschenhagen, G. Filippatos, L. Gepstein, J. Hulot, R. Knöll, C. Kupatt, Wolfgang A. Linke, Christine E. Seidman, C. Tocchetti, Jolanda Velden, R. Walsh, P. Seferovic, T. Thum   +18 more
semanticscholar   +1 more source

Validation of the new American College of Cardiology/American Heart Association Guidelines for the risk stratification of sudden cardiac death in a large Mediterranean cohort with Hypertrophic Cardiomyopathy

Hellenic Journal of Cardiology, 2022
Background: The aim of our study was to assess the performance of the new American College of Cardiology (ACC)/American Heart Association (AHA) Guidelines, with respect to sudden cardiac death (SCD) prevention, in comparison with the established risk ...
Thomas Zegkos, Georgios Tziomalos, Despoina Parcharidou, Dimitris Ntelios, Christos A. Papanastasiou, Efstratios Karagiannidis, Thomas Gossios, Pavlos Rouskas, Sotiris Katranas, Stilianos Paraskevaidis, Haralambos Karvounis, Georgios Efthimiadis   +11 more
doaj  

Transcriptome data analysis of primary cardiomyopathies reveals perturbations in arachidonic acid metabolism

Frontiers in Cardiovascular Medicine, 2023
IntroductionCardiomyopathies are complex heart diseases with significant prevalence around the world. Among these, primary forms are the major contributors to heart failure and sudden cardiac death.
Pankaj Kumar Chauhan, Ramanathan Sowdhamini, Ramanathan Sowdhamini, Ramanathan Sowdhamini   +3 more
doaj   +1 more source

CARDIOMYOPATHY: The diagnosis of hypertrophic cardiomyopathy [PDF]

Heart, 2001
Although the pathology of hypertrophic cardiomyopathy (HCM) was first described by French pathologists in the mid 19th century, it remained for the virtually simultaneous reports of Brock and Teare in England some 43 years ago to bring modern attention to this fascinating entity.1 2 Subsequent to these surgical1 and pathological2 observations, there ...
openaire   +3 more sources