ICD Outcome in Pediatric Cardiomyopathies
Background: Pediatric patients with cardiomyopathies are at risk of malignant arrhythmias and sudden cardiac death (SCD). An ICD may prevent SCD. The aim of this study was to evaluate ICD implantation outcomes, and to compare transvenous and subcutaneous
Massimo Stefano Silvetti+10 more
doaj +1 more source
Molecular analysis of sarcomeric and non-sarcomeric genes in patients with hypertrophic cardiomyopathy. [PDF]
Background: Hypertrophic cardiomyopathy (HCM) is a common genetic heart disorder characterized by unexplained left ventricle hypertrophy associated with non-dilated ventricular chambers.
BOTTILLO, IRENE+12 more
core +1 more source
Epidemiology of cardiomyopathies and incident heart failure in a population-based cohort study
Aims The population prevalence of cardiomyopathies and the natural history of symptomatic heart failure (HF) and arrhythmia across cardiomyopathy phenotypes is poorly understood.
J. Brownrigg+6 more
semanticscholar +1 more source
CARDIOMYOPATHY: The cardiomyopathies: an overview [PDF]
The recent revision (table 1) of the definition of a cardiomyopathy by the World Health Organization1 recognises that ventricular dysfunction can result from a failure to correct volume or pressure overload in valve disease or to control hypertension. Loss of myocardium caused by coronary artery disease also leads to severe ventricular dysfunction. All
openaire +2 more sources
Abnormal ECG Findings in Athletes: Clinical Evaluation and Considerations. [PDF]
PURPOSE OF REVIEW: Pre-participation cardiovascular evaluation with electrocardiography is normal practice for most sporting bodies. Awareness about sudden cardiac death in athletes and recognizing how screening can help identify vulnerable athletes have
A Biffi+83 more
core +1 more source
Testosterone, cardiomyopathies, and heart failure: a narrative review
Testosterone exerts an important regulation of cardiovascular function through genomic and nongenomic pathways. It produces several changes in cardiomyocytes, the main actor of cardiomyopathies, which are characterized by pathological remodeling ...
R. Diaconu+3 more
semanticscholar +1 more source
This simulation is appropriate for emergency medicine (EM) residents of all levels.Peripartum cardiomyopathy (PPCM) is a rare, idiopathic condition that occurs in the mother around the time of childbirth. Heart failure with reduced ejection fraction and/or reduced systolic function diagnosed in patients during the last month of pregnancy or up to five ...
Morris, Victoria L+4 more
openaire +4 more sources
A green tea extract catechin EGCg: Therapeutic potential for pediatric cardiomyopathies
Cardiomyopathies comprise a group of disorders wherein the primary defect is in cardiac myocytes. The common forms of pediatric cardiomyopathies, classified according to their morphological and functional manifestations, include dilated cardiomyopathy ...
Junjun Quan+4 more
doaj +1 more source
Investigating the role of uncoupling of troponin I phosphorylation from changes in myofibrillar Ca(2+)-sensitivity in the pathogenesis of cardiomyopathy. [PDF]
Contraction in the mammalian heart is controlled by the intracellular Ca2+ concentration as it is in all striated muscle, but the heart has an additional signalling system that comes into play to increase heart rate and cardiac output during exercise or ...
Marston, SB, Messer, AE
core +2 more sources
Complexity in genetic cardiomyopathies and new approaches for mechanism-based precision medicine
Thousands of variants are associated with genetic cardiomyopathies; however, the mechanisms driving these progressive, heterogeneous diseases are not well understood.
M. Greenberg, J. Tardiff
semanticscholar +1 more source