Results 41 to 50 of about 118,306 (318)
Sex‐Related Differences in Genetic Cardiomyopathies
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022 Cardiomyopathies are a heterogeneous collection of diseases that have in common primary functional and structural abnormalities of the heart muscle, often genetically determined.
Alessia Argirò +8 more
doaj +1 more source
Animal Models and Experimental Medicine, Volume 5, Issue 6, Page 542-549, December 2022., 2022 Schematic diagram showing RHAU can bind and unwind the G4 “knots” to modulate embryonic development and post‐natal organ function. Deficiency of RHAU gives rise to embryonic lethality, impaired organogenesis and organ dysfunction. RHAU modulates Nkx2‐5 mRNA and Yap1 mRNA at the post‐transcriptional level and facilitates the transcription of c‐Kit and ...
Chensi Yang +5 more
wiley +1 more source
Human-induced pluripotent stem cells in modeling inherited cardiomyopathies
Journal of the Practice of Cardiovascular Sciences, 2015 Our current understanding of molecular mechanisms of cardiomyopathies has been elucidated from genetic animal models. Induced pluripotent stem cells (iPSCs) can provide a platform to improve our understanding of familial cardiomyopathies diseases.
Subhoshree Ghose +3 more
doaj +1 more source
Reviews in Cardiovascular MedicineBackground: Cardiac myosin inhibitors (CMIs), including Mavacamten and Aficamten, have emerged as a groundbreaking treatment for hypertrophic cardiomyopathy (HCM).
Ali Amr +7 more
doaj +1 more source
Cirrhotic cardiomyopathy [PDF]
Orphanet Journal of Rare Diseases, 2007 Abstract Cirrhotic cardiomyopathy is the term used to describe a constellation of features indicative of abnormal heart structure and function in patients with cirrhosis. These include systolic and diastolic dysfunction, electrophysiological changes, and macroscopic and microscopic structural changes.
Fouad Tamer R, Baik Soon, Lee Samuel S
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Diagnosis of cardiomyopathies: tips and tricks for internists and general practitioners
Cardiogenetics, 2017 Cardiomyopathies are little known to internists and general practitioners (GPs), and not always able to arouse the interest of cardiologists. Probably, this happens because cardiomyopathies are perceived as rare and complex disorders, a prerogative of a ...
Giuseppe Palmiero +2 more
doaj +1 more source
Dilated cardiomyopathies and non-compaction cardiomyopathy [PDF]
Herz, 2020 AbstractDilated cardiomyopathy (DCM) is the most common form of cardiomyopathy and one of the most common causes of heart failure. It is characterized by left or biventricular dilation and a reduced systolic function. The causes are manifold and range from myocarditis to alcohol and other toxins, to rheumatological, endocrinological, and metabolic ...
Anja Hänselmann +3 more
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Electromechanical modeling of human ventricles with ischemic cardiomyopathy: numerical simulations in sinus rhythm and under arrhythmia [PDF]
arXiv, 2021 We developed a novel patient-specific computational model for the numerical simulation of ventricular electromechanics in patients with ischemic cardiomyopathy (ICM). This model reproduces the activity both in sinus rhythm (SR) and in ventricular tachycardia (VT).
arxiv
The Feline Cardiomyopathies: 2. Hypertrophic cardiomyopathy
Journal of Feline Medicine and Surgery, 2021 Practical relevance: Hypertrophic cardiomyopathy (HCM) is the most common form of feline cardiomyopathy observed clinically and may affect up to approximately 15% of the domestic cat population, primarily as a subclinical disease. Fortunately, severe HCM, leading to heart failure or arterial thromboembolism (ATE), only occurs in a small proportion of ...
Etienne Côté, Mark D Kittleson
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