Results 161 to 170 of about 46,771 (265)

Prolonged postnatal adaptation and enhanced prevalence of congenital heart diseases due to altitude may contribute to newborn mortality in Bolivia

open access: yesExperimental Physiology, EarlyView.
Abstract Highland populations suffer from significant infant mortality due to chronic ambient hypoxia, which increases the risk of congenital heart disease (CHD) and neonatal pulmonary hypertension. Neither the prevalence of these conditions nor the effectiveness of neonatal cardiac screening to identify CHD or pulmonary hypertension among neonates ...
Alexandra Heath   +12 more
wiley   +1 more source

The potential of CRISPR-Cas9 in cardiovascular medicine: a focus on hereditary cardiomyopathies. [PDF]

open access: yesAnn Med Surg (Lond)
Rasheed S   +8 more
europepmc   +1 more source

Heart dysfunction in a rat model with autosomal recessive polycystic kidney disease

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Our results demonstrate a diastolic dysfunction in animals with severe kidney disease. Moreover, chronic kidney disease (CKD)‐induced heart fibrosis and hypertrophy are associated with a dysregulation of cardiokine signalling in autosomal recessive polycystic kidney disease (ARPKD) animals. Created using BioRender.com.
Nathalie Gayrard   +11 more
wiley   +1 more source

Mitochondrial Complex I Deficiency: Unraveling the Relevance of NDUFAF1 in Pediatric Hypertrophic Cardiomyopathy

open access: yesAmerican Journal of Medical Genetics Part A, Volume 197, Issue 5, May 2025.
ABSTRACT Hypertrophic cardiomyopathy (HCM) is rare in childhood, but it is associated with significant morbidity and mortality. Genetic causes of HCM are mostly related to sarcomeric genes abnormalities; however, syndromic, metabolic, and mitochondrial disorders play an important role in its etiopathogenesis in pediatric patients.
Silvia Kalantari   +12 more
wiley   +1 more source

Reproducibility of Cardiac Multifrequency MR Elastography in Assessing Left Ventricular Stiffness and Viscosity

open access: yesJournal of Magnetic Resonance Imaging, Volume 61, Issue 5, Page 2146-2154, May 2025.
Background Cardiac magnetic resonance elastography (MRE) shows promise in assessing the mechanofunctional properties of the heart but faces clinical challenges, mainly synchronization with cardiac cycle, breathing, and external harmonic stimulation.
Johannes Castelein   +11 more
wiley   +1 more source

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