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Lidocaine and Pinacidil Added to Blood versus Crystalloid Cardioplegic Solutions: Study in Isolated Hearts [PDF]

open access: diamondBrazilian Journal of Cardiovascular Surgery, 2018
Objective: The present study aimed the functional recovery evaluation after long term of cardiac arrest induced by Custodiol (crystalloid-based) versus del Nido (blood-based) solutions, both added lidocaine and pinacidil as cardioplegic agents ...
Helison Pereira do Carmo   +6 more
doaj   +3 more sources

Relevance and Recommendations for the Application of Cardioplegic Solutions in Cardiopulmonary Bypass Surgery in Pigs [PDF]

open access: yesBiomedicines, 2021
Cardioplegic solutions play a major role in cardiac surgery due to the fact that they create a silent operating field and protect the myocardium against ischemia and reperfusion injury.
Anna Glöckner   +6 more
doaj   +2 more sources

Single-centre, single-blind, randomized, active-controlled phase-3 non-inferiority study to investigate the safety and efficacy of the cardioplegic solution Cardioplexol™ [PDF]

open access: goldFrontiers in Cardiovascular Medicine
ObjectivesEffective and reliable cardioplegic cardiac arrest is crucial for maximizing myocardial protection and preserving postoperative contractile function. Aim of this study was to demonstrate, in line with an ongoing European registration procedure,
Hendrik T. Tevaearai Stahel   +12 more
doaj   +3 more sources

The relative buffering power of cardioplegic solutions

open access: bronzeThe Journal of Thoracic and Cardiovascular Surgery, 1987
Those factors that prolong myocardial tolerance to global ischemia constitute an important prerequisite for effective cardioplegia. This study contrasts the relative buffering power of bicarbonate-based and tromethamine-based hyperkalemic crystalloid cardioplegic solution with histidine protein-type buffer (Bretschneider) solution.
J. Yasha Kresh   +4 more
openalex   +4 more sources

Heterogeneous distribution of cardioplegic solution in pigs [PDF]

open access: bronzeBritish Journal of Anaesthesia, 2001
Septal dyskinesia in the left ventricle is detected frequently in many patients after open-heart surgery. The present study was designed to determine whether the antegrade delivery of cardioplegic solution to the regional wall categorized in echocardiography is homogeneous, and whether the distribution to the septal wall differs from that to the ...
Jisu Han   +6 more
openalex   +4 more sources

“Kirsch” cardioplegic solution

open access: bronzeThe Journal of Thoracic and Cardiovascular Surgery, 1979
F. Vermeulen
openalex   +4 more sources

Mechanisms of myocardial protection by adenosine-supplemented cardioplegic solution: Myofilament and metabolic responses [PDF]

open access: bronze, 2000
Objective: Adenosine supplementation of cardioplegic solutions in cardiac operations improves postarrest myocardial recovery after cardioplegic arrest and reperfusion; however, the mechanism of the action of adenosine remains unknown.
Bernard G. Fogelson   +2 more
openalex   +3 more sources

Celsior® vs. St Thomas® cardioplegia: analysis of myocardial protection and clinical safety in neonates [PDF]

open access: yesFrontiers in Pediatrics
ObjectiveTo compare the effectiveness and safety of Celsior® crystalloid solution to St Thomas® solution as cardioplegia in pediatric arterial switch surgery.MethodsA retrospective study was conducted on 180 patients who underwent arterial switch ...
Nicolae Cristian Bulescu   +8 more
doaj   +2 more sources

Efficacy and safety of the blood-based cardioplegia solution Huaxi-1 in cardiopulmonary bypass surgery: protocol for a multicentre randomised controlled trial [PDF]

open access: yesBMJ Open
Introduction Cardioplegia during cardiopulmonary bypass is essential for ensuring a surgical field free of blood and cardiac movement. Numerous cardioplegia solutions are available, but consensus guidelines about the safest or most effective do not exist.
Tao Chen   +16 more
doaj   +2 more sources

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