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Relevance and Recommendations for the Application of Cardioplegic Solutions in Cardiopulmonary Bypass Surgery in Pigs [PDF]

open access: goldBiomedicines, 2021
Cardioplegic solutions play a major role in cardiac surgery due to the fact that they create a silent operating field and protect the myocardium against ischemia and reperfusion injury.
Anna Glöckner   +6 more
doaj   +4 more sources

How different cardioplegic solutions influence genes expression and cytokine response in an immature rat heart model of ischemia/reperfusion? [PDF]

open access: yesPLoS ONE
IntroductionThe use of cardioplegia not only achieves cardiac arrest but also minimizes ischemic/reperfusion (I/R) injury, potentially improving short- or long-term outcomes.
Arslan Mamedov   +9 more
doaj   +3 more sources

Lidocaine and Pinacidil Added to Blood versus Crystalloid Cardioplegic Solutions: Study in Isolated Hearts [PDF]

open access: yesBrazilian Journal of Cardiovascular Surgery, 2018
Objective: The present study aimed the functional recovery evaluation after long term of cardiac arrest induced by Custodiol (crystalloid-based) versus del Nido (blood-based) solutions, both added lidocaine and pinacidil as cardioplegic agents ...
Helison Pereira do Carmo   +6 more
doaj   +2 more sources

Comparable renal effects of histidine-tryptophan-ketoglutarate and DelNido cardioplegia in a porcine model of cardiac arrest [PDF]

open access: yesRenal Failure
Acute kidney injury (AKI) is a serious complication following on-pump cardiac surgery. Choosing the cardioplegic solution with the most appropriate myocardial protection and lowest grade of AKI could improve patient outcome.
Maja-Theresa Dieterlen   +8 more
doaj   +2 more sources

Comparison of Clinical Outcomes of Two Different Cardioplegic Solutions in Patients Undergoing Coronary Artery Bypass Graft Surgery; A randomize clinical trial

open access: goldAdvanced Biomedical Research
Background: Usually, manual cardioplegic solutions with low magnesium and lidocaine, and corporate solutions with high magnesium and procaine, are the only common solutions used to induce cardiac arrest during coronary artery bypass graft (CABG) surgery.
Alireza Hosseini   +4 more
doaj   +2 more sources

Comparative Effects of HTK and St. Thomas Cardioplegia on Myocardial Outcomes and Sodium Balance in Pediatric Tetralogy of Fallot Surgery [PDF]

open access: yesJournal of Multidisciplinary Healthcare
Li-Jun Liang,1 Zhi-Lan Ding,1 Li-Fen Zhang,1 Cai-Xia Liu,1 Hong-Wei Xi,2 Jin-Ming Yang1 1Department of Cardiothoracic Surgery, Shanxi Children’s Hospital, Shanxi Women and Children Hospital, Taiyuan, Shanxi Province, 030025, People’s Republic of China ...
Liang LJ   +5 more
doaj   +2 more sources

Heterogeneous distribution of cardioplegic solution in pigs [PDF]

open access: bronzeBritish Journal of Anaesthesia, 2001
Septal dyskinesia in the left ventricle is detected frequently in many patients after open-heart surgery. The present study was designed to determine whether the antegrade delivery of cardioplegic solution to the regional wall categorized in echocardiography is homogeneous, and whether the distribution to the septal wall differs from that to the ...
Jisu Han   +6 more
openalex   +3 more sources

Molecular and Cellular Mechanisms of Cardioplegic Protection in Surgical Myocardial Revascularization [PDF]

open access: yesCells
Coronary artery bypass grafting (CABG) remains the gold standard for patients with advanced multivessel coronary artery disease. Optimal myocardial protection versus ischemia during reversible and controlled cardiac arrest is a cornerstone of successful ...
Dejan M. Lazović   +8 more
doaj   +2 more sources

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