Results 61 to 70 of about 3,809 (263)

The use of blood and crystalloid cardioplegia in adult open-heart surgery on postsurgical outcomes: A systematic review of atrial fibrillation incidence, myocardial infarction, inotropic use, length of stay in ICU, and postoperative mortality

Bali Journal of Anesthesiology, 2022
Background: Myocardial ischemia can occur due to hypotension, shock, coronary heart disease, and aortic cross-clamping during open-heart surgery using a cardiopulmonary bypass machine. As the cardioprotective method, cardioplegia is classified into blood
Bambang Novianto Putro, Jefferson K Hidayat, Ratna Farida Soenarto   +2 more
doaj   +1 more source

Redo mitral valve repair under repeat cardiopulmonary bypass in a dog

Veterinary Surgery, Volume 54, Issue 8, Page 1625-1634, November 2025.
Abstract Objective To report the lifelong outcome of a redo mitral valve repair performed under repeat cardiopulmonary bypass (CPB) in a dog. Study design Case report. Animal An 11‐year‐old, 4.0‐kg neutered male Chihuahua, previously treated with surgical mitral valve repair for myxomatous mitral valve disease at the age of eight, presented with ...
Kippei Mihara, Yuya Suzuki, Kentaro Ito
wiley   +1 more source

Diazoxide maintains human myocyte volume homeostasis during stress [PDF]

, 2012
BACKGROUND: Exposure to hypothermic hyperkalemic cardioplegia, hyposmotic stress, or metabolic inhibition results in significant animal myocyte swelling (6% to10%) and subsequent reduced contractility (10% to 20%).
Al-Dadah, Ashraf S, Damiano, Ralph J, Jr., Lawton, Jennifer S, Maffit, Sara K, Schuessler, Richard B, Sellitto, Angela D   +5 more
core   +2 more sources

Multiomics investigation of the female hypertensive human heart

Physiological Reports, Volume 13, Issue 19, October 2025.
Abstract Hypertension affects 1 in 2 adults in the United States and is the leading risk factor for myocardial infarction and chronic kidney disease. While animal models have advanced our understanding of the effects of hypertension on the heart, molecular insight from human cardiovascular tissues is currently lacking.
Zachary J. Milstone, Jesse D. Moreira‐Bouchard, Karan K. Smith, Anjali Anilkumar, Adam C. Gower, Yuriy Alekseyev, Jason A. Cunha, Nathaniel Fisher, Levi Legler, Joshua Lepson, Brian S. Tao, Christopher Williams, Emelia J. Benjamin, Daniel Levy, Richard N. Mitchell, Robert F. Padera, Hardik Shah, Seung Hoan Choi, Deepa M. Gopal, Nathan R. Tucker, Jessica L. Fetterman   +20 more
wiley   +1 more source

Efeitos das cardioplegias sangüínea e cristalóide no miocárdio hipertrófico de coelho: avaliação estrutural e ultra-estrutural Effects of myocardial protection in hypertrophic rabbit hearts: structural and ultra structural analysis

Brazilian Journal of Cardiovascular Surgery, 2007
OBJETIVO: Comparar e avaliar experimentalmente as alterações estruturais e ultra-estruturais em corações hipertrofiados isolados de coelhos submetidos à parada protegida pela solução de cardioplegia sangüínea e cardioplegia cristalóide.
Elthon Silveira Cressoni, Luiz Ernesto Avanci, Domingo Marcolino Braile, Ana Paula Marques Lima-Oliveira, Sebastião Roberto Taboga, Antonio Sérgio Martins, Rosa Sayoko Kawasaki Oyama, Marcos Aurélio Barbosa de Oliveira   +7 more
doaj   +1 more source

The Effect of High-Dose Vitamin C on Biochemical Markers of Myocardial Injury in Coronary Artery Bypass Surgery [PDF]

Brazilian Journal of Cardiovascular Surgery, 2019
Objective: To evaluate the effect of high-dose vitamin C on cardiac reperfusion injury and plasma levels of creatine kinase-muscle/brain (CK-MB), troponin I, and lactate dehydrogenase (LDH) in patients undergoing coronary artery bypass grafting (CABG ...
Nafiseh Emadi, Mohammad Hasan Nemati, Mohammad Ghorbani, Elahe Allahyari   +3 more
doaj   +1 more source

Evaluation of sanguineous and crystalloid cardioplegic solutions during total heart-lung bypass in dogs [PDF]

, 2009
Twenty-four mongrel dogs were subjected to sanguineous and crystalloid cardioplegia for a period of thirty minutes at 20°C and 25°C systemic hypothermia during cardiopulmonary bypass. Cardioplegic solutions were administered at 4°C to induce cardioplegia.
Archibald, D., George, R. S., Jayaprakash, R., Radhakrishnan , C., Ramanujam, K.   +4 more
core  

Differential Effects of Tyrosine Kinase Inhibitors on Volume-sensitive Chloride Current in Human Atrial Myocytes: Evidence for Dual Regulation by Src and EGFR Kinases [PDF]

, 2004
To determine whether protein tyrosine kinase (PTK) modulates volume-sensitive chloride current (I Cl.vol) in human atrial myocytes and to identify the PTKs involved, we studied the effects of broad-spectrum and selective PTK inhibitors and the protein ...
Baumgarten, CM, Chiu, SW, Du, XL, Gao, Z, Lau, CP, Li, GR, Tse, HF   +6 more
core   +3 more sources

The relative buffering power of cardioplegic solutions

The Journal of Thoracic and Cardiovascular Surgery, 1987
Those factors that prolong myocardial tolerance to global ischemia constitute an important prerequisite for effective cardioplegia. This study contrasts the relative buffering power of bicarbonate-based and tromethamine-based hyperkalemic crystalloid cardioplegic solution with histidine protein-type buffer (Bretschneider) solution.
J Y, Kresh, C, Nastala, P C, Bianchi, S M, Goldman, S K, Brockman   +4 more
openaire   +2 more sources

Dexrazoxane protects against doxorubicin‐induced cardiotoxicity in susceptible human living myocardial slices: A proof‐of‐concept study

British Journal of Pharmacology, Volume 182, Issue 18, Page 4262-4280, September 2025.
Abstract Background and Purpose The increasing number of cancer survivors has caused growing concern over chemotherapy‐induced cardiotoxicity. This study aimed to investigate a novel human model of cardiotoxicity and explore cardioprotection. Experimental Approach Living myocardial slices (LMS) were obtained from explanted end‐stage heart failure ...
Jort S. A. van der Geest, Ilse R. Kelters, Bauke Arends, Willem B. van Ham, Ernest Diez Benavente, Thirza A. Lapré, Petra van der Kraak, Pim van der Harst, Arco J. Teske, Andreas Dendorfer, M. Mostafa Mokhles, Pieter A. Doevendans, Teun P. de Boer, Linda W. van Laake, Joost P. G. Sluijter, Vasco Sampaio‐Pinto   +15 more
wiley   +1 more source