2,3-Butanedione monoxime attenuates the β-adrenergic response of the L-type Ca2+ current in rat ventricular cardiomyocytes [PDF]
Context: 2,3-Butanedione monoxime (BDM), an uncoupler of cardiac contraction, is commonly used in enzymatic dissociations to prevent hypercontraction of cardiomyocytes and in cardioplegic solutions to decrease oxygen demand during surgery.
Julio Alvarez-Collazo +3 more
doaj
OBJECTIVE: To analyze the behavior of troponin (TROP I) and CKMB mass (CKMBm) in regards to the addition of magnesium in cardioplegic solutions; and also the influence of per-operative factors.
Pedro Rafael Salerno +7 more
doaj +1 more source
Cardioplegia at subnormothermia facilitates rapid functional resuscitation of hearts preserved in SOMAH for transplants [PDF]
Objectives: Hearts preserved ex vivo at 4°C undergo time-dependent irreversible injury due to extreme hypothermia. Studies using novel organ preservative solution SOMAH, suggest that hearts are optimally ‘preserved’ at subnormothermic temperature of 21°C.
Lowalekar, Samar K +2 more
core +1 more source
Foi avaliado, experimentalmente, o grau de proteção miocárdica oferecido por soluções cardioplégicas e hipotermia, à anóxia induzida pela interrupção do fluxo sangüíneo coronário em 20 cães. A isquemia miocárdica foi obtida através do pinçamento da aorta
Luis Alberto Dallan +6 more
doaj
Recovery of donor hearts after circulatory death with normothermic extracorporeal machine perfusion [PDF]
OBJECTIVES A severe donor organ shortage leads to the death of a substantial number of patients who are listed for transplantation. The use of hearts from donors after circulatory death could significantly expand the donor organ pool, but due to ...
Bogdanova, Anna +5 more
core
Comparative Study between Cardioplegic Solution (Custodiol) versus Conventional Cardioplegic Solutions in CABG Patients [PDF]
Y.E. Risk +3 more
openaire +1 more source
Replacement of pulmonary artery trunk in sheep using tubular valved heterograft in non-aldehydic preservation [PDF]
INTRODUCTION: The cardiac bioprostheses are related to thromboembolic events, infectious and degenerative diseases. Wear is mainly attributed to the denaturation of collagen. Glutaraldehyde, the predominant method of preservation of bioprostheses, favors
Almeida, Marco Antônio Cardoso de +7 more
core +3 more sources
Organ transplantation--then and now. [PDF]
The last 25 years have seen amazing progress in transplantation--from the development of techniques for immunosuppression to methods for organ removal and preservation.
Makowka, L, Starzl, TE
core
Aortic stenosis and aortic regurgitation express different titin isoforms: Differences and relationships with functional and geometric characteristics [PDF]
Background-Titin represents an important biomechanical sensor which determines compliance and diastolic/ systolic function of the left ventricle (LV). To assess the different titin-isoform expression and the relationships with functional and geometric ...
Antignano, Anita +5 more
core +1 more source

