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Cardioprotection With Grapes

Journal of Cardiovascular Pharmacology, 2002
Epidemiologic studies suggest that mild-to-moderate wine consumption is associated with a reduced incidence of mortality and morbidity from coronary heart disease. Because wines are produced from grapes, this study was done to determine whether the grapes were equally cardioprotective.
Jianhua, Cui   +4 more
openaire   +2 more sources

Cardioprotection: emerging pharmacotherapy

Expert Opinion on Pharmacotherapy, 2001
By the year 2020, it is predicted that acute coronary occlusion will be the major cause of death in the world. Recent advances in reperfusion therapy have substantially improved survival of patients with acute coronary syndromes. While early reperfusion reduces mortality, a time limitation exists with regard to myocardial salvage.
R J, Gumina   +3 more
openaire   +2 more sources

ARB and Cardioprotection

Cardiovascular Drugs and Therapy, 2012
A growing body of evidence has suggested that the use of angiotensin II (Ang II) type 1 (AT1) receptor blockers (ARBs) leads to a significant decrease in mortality and morbidity in patients with congestive heart failure. The AT1 receptor is a seven-transmembrane G protein-coupled receptor, and is involved in regulating the physiological and ...
Hiroshi, Akazawa   +4 more
openaire   +2 more sources

Exercise and cardioprotection

Current Opinion in Cardiology, 2002
A wealth of data indicates that performing regular exercise is an important lifestyle modification to prevent cardiovascular disease. Although not fully understood, the cardioprotection by regular exercise may be exerted synergistically through improvement in many risk factors associated with cardiovascular disease.
Scott K, Powers   +3 more
openaire   +2 more sources

Cardioprotective MicroRNAs

Pediatric Cardiology, 2011
MicroRNAs (miRNAs) are involved in almost every aspect of a mammalian cell's functionality, from stem cell differentiation to aging and pathogenesis; however, their role in immediate cell signaling is less defined. This has been recently demonstrated by the rapid increase or decrease of miR-21's abundance within minutes of activation or inhibition of ...
openaire   +2 more sources

Mitochondria and cardioprotection

Heart Failure Reviews, 2007
Major factors linking mitochondrial dysfunction with myocardial injury are analyzed along with protective mechanisms elicited by endogenous processes and pharmacological treatments. In particular, a reduced rate of ATP hydrolysis and a slight increase in ROS formation appear to represent the prevailing components of self-defense mechanisms, especially ...
DI LISA, FABIO   +4 more
openaire   +5 more sources

Aging and cardioprotection

Journal of Applied Physiology, 2007
Advanced age is a strong independent predictor for death, disability, and morbidity in patients with structural heart disease. With the projected increase in the elderly population and the prevalence of age-related cardiovascular disabilities worldwide, the need to understand the biology of the aging heart, the mechanisms for age-mediated cardiac ...
Arshad, Jahangir   +2 more
openaire   +2 more sources

Future Cardioprotective Considerations

Journal of Cardiac Surgery, 1993
Remarkable strides have been made in perioperative myocardial protection for heart operations. Recent advances in understanding the physiology of myocardial ischemia and its protective responses suggest that there is a possibility for further improvement.
A S, Wechsler, A, Abd-Elfattah
openaire   +2 more sources

Tocotrienols in Cardioprotection

2007
Tocotrienols, a group of Vitamin E stereoisomers, offer many health benefits including their ability to lower cholesterol levels, and provide anticancer and tumor-suppressive activities. Several recent studies determined the cardioprotective abilities of tocotrienols, although the number is only 1% compared to the study with tocopherols.
Samarjit, Das   +2 more
openaire   +3 more sources

KININS AND CARDIOPROTECTION

Pharmacological Research, 1997
During the past decade it was recognised that kinins are potent endogenous vasoactive peptides with important cardioprotective actions which are of therapeutic relevance in the acute and chronic beneficial effects of ACE inhibitors. The effect of kinins is mediated through the release of autocoids from the endothelium, particularly nitric oxide (NO ...
K J, Wirth   +3 more
openaire   +2 more sources

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