Results 141 to 150 of about 31,146 (236)

Rosemary metabolite carnosic acid opens Kv1.1 via its voltage sensor and corrects Kv1.1‐linked episodic ataxia in mice

British Journal of Pharmacology, Volume 183, Issue 20, Page 6179-6198, October 2026.
Background and Purpose Episodic ataxia type 1 (EA1) is an autosomal dominant neurological disorder caused primarily by loss‐of‐function mutations in the voltage‐gated potassium channel Kv1.1 (KCNA1). Small molecules that restore Kv1.1 activity hold promise as targeted therapies for EA1, yet current pharmacological strategies remain limited ...
Rían W. Manville, Ryan F. Yoshimura, Hanh A. Nguyen, Ruiming Zhao, Derk J. Hogenkamp, Steve A. N. Goldstein, Geoffrey W. Abbott   +6 more
wiley   +1 more source

FGF21/sirtuin 1 axis mediates the cardioprotective effects of high‐intensity interval training against doxorubicin‐induced cardiotoxicity by reducing inflammatory and oxidative stress

Experimental Physiology, Volume 111, Issue 10, Page 4409-4420, 1 October 2026.
Abstract Doxorubicin (DOX) is a potent anthracycline chemotherapeutic agent, but its clinical use is limited by cumulative cardiotoxicity. Exercise, particularly high‐intensity interval training (HIIT), has emerged as an effective non‐pharmacological strategy to counteract chemotherapy‐induced cardiac injury.
Mahdiyeh Farahani, Abbas Ali Gaeini, Alireza Ghardashi Afousi, Mahboobeh Borjian Fard   +3 more
wiley   +1 more source

Cost-effectiveness of strain-targeted cardioprotection for prevention of chemotherapy-induced cardiotoxicity

, 2016
Background: Cancer chemotherapy increases the risk of heart failure. This cost-effectiveness model compared strain-guided cardioprotection with other protective strategies using a health care payer perspective and five-year time horizon.
Nolan, Mark T., Si, Lei (R20827), Plana, Juan C., Shaw, Leslee, Thavendiranathan, Paaladinesh, Marwick, Thomas H.   +5 more
core   +1 more source

A Potential Role of Adenosine A 2 b Receptor in Mediating Acupuncture Pretreatment Induced Cardioprotection via Influencing Intracellular Calcium Regulator

针刺研究, 2018
It has been shown that ischemia preconditioning(IPC)can attenuate the myocardial injury induced by ischemic and reperfusion.But it was rarely used in clinic due to its inoperability.Previous studies indicate that electroacupuncture(EA)pretreatment can ...
DAI Qiu-fu, WANG Yuan-yuan, LIU Qun, XIN Juan-juan, LU Feng-yan, CUI Jing-jing, WU Shu-yang, ZHOU Chen, ZHAO Yu-xue, GAO Jun-hong, YU Xiao-chun   +10 more
doaj   +2 more sources

The role of signal transducer and activator of transcription-3 (STAT-3) in ischaemic and pharmacological postconditioning [PDF]

, 2011
Includes abstract. Includes bibliographical references (leaves 131-147)
Somers, Sarin J
core  

A link between ATP and SUR2A:a novel mechanism explaining cardioprotection at high altitude [PDF]

, 2015
Sukhodub, Andriy, Mohammed Abdul, Khaja Shameem, Du, Qingyou, Jovanovic, Aleksandar, Jovanovic, Sofija   +4 more
core   +1 more source

SURPASS‐CVOT and the Emerging Biology of Cardiometabolic Benefit

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 8753-8756, October 2026.
Salvatore Corrao, Francesco Cosentino, Massimo Federici   +2 more
wiley   +1 more source

USAGE OF CARDIOPROTECTION PRINCIPLES IN TREATING CHRONIC HEART FAILURE

Российский кардиологический журнал, 2000
Usage of cardioprotection principles in treating chronic heart failure.
M. A. Gurevich, N. P. Sanina
doaj  

Reperfusion Injury and Infarct Size: Why Translation has Been Difficult, and How We Move Forward. [PDF]

Curr Cardiol Rep
Bulluck H, Hausenloy DJ.
europepmc   +1 more source

Historical account of reperfusion therapy and the development of cardioprotection beyond reperfusion. [PDF]

Basic Res Cardiol
Heusch G, Kleinbongard P, Gersh BJ.
europepmc   +1 more source